A cellular taxonomy of the bone marrow stroma in homeostasis and leukemia N Baryawno, D Przybylski, MS Kowalczyk, Y Kfoury, N Severe, ... Cell 177 (7), 1915-1932. e16, 2019 | 765 | 2019 |
Mesenchymal cell contributions to the stem cell niche Y Kfoury, DT Scadden Cell stem cell 16 (3), 239-253, 2015 | 596 | 2015 |
Inhibition of dihydroorotate dehydrogenase overcomes differentiation blockade in acute myeloid leukemia DB Sykes, YS Kfoury, FE Mercier, MJ Wawer, JM Law, MK Haynes, ... Cell 167 (1), 171-186. e15, 2016 | 484 | 2016 |
Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin R Palchaudhuri, B Saez, J Hoggatt, A Schajnovitz, DB Sykes, TA Tate, ... Nature biotechnology 34 (7), 738-745, 2016 | 232 | 2016 |
Hematopoietic stem cell niche in health and disease J Hoggatt, Y Kfoury, DT Scadden Annual Review of Pathology: Mechanisms of Disease 11 (1), 555-581, 2016 | 192 | 2016 |
Proximity-based differential single-cell analysis of the niche to identify stem/progenitor cell regulators L Silberstein, KA Goncalves, PV Kharchenko, R Turcotte, Y Kfoury, ... Cell stem cell 19 (4), 530-543, 2016 | 175 | 2016 |
Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment Y Kfoury, N Baryawno, N Severe, S Mei, K Gustafsson, T Hirz, T Brouse, ... Cancer cell 39 (11), 1464-1478. e8, 2021 | 163 | 2021 |
Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-κB activation R Nasr, E Chiari, M El-Sabban, R Mahieux, Y Kfoury, M Abdulhay, ... Blood 107 (10), 4021-4029, 2006 | 134 | 2006 |
Stress-induced changes in bone marrow stromal cell populations revealed through single-cell protein expression mapping N Severe, NM Karabacak, K Gustafsson, N Baryawno, G Courties, ... Cell stem cell 25 (4), 570-583. e7, 2019 | 125 | 2019 |
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses T Hirz, S Mei, H Sarkar, Y Kfoury, S Wu, BM Verhoeven, AO Subtelny, ... Nature communications 14 (1), 663, 2023 | 104 | 2023 |
Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia H El Hajj, M El-Sabban, H Hasegawa, G Zaatari, J Ablain, ST Saab, ... Journal of Experimental Medicine 207 (13), 2785-2792, 2010 | 103 | 2010 |
Efficacy and mechanism of action of the proteasome inhibitor PS-341 in T-cell lymphomas and HTLV-I associated adult T-cell leukemia/lymphoma R Nasr, ME El-Sabban, JA Karam, G Dbaibo, Y Kfoury, B Arnulf, ... Oncogene 24 (3), 419-430, 2005 | 102* | 2005 |
Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome Y Kfoury, R Nasr, A Favre-Bonvin, M El-Sabban, N Renault, ML Giron, ... Oncogene 27 (12), 1665-1676, 2008 | 89 | 2008 |
ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation Z Dassouki, U Sahin, H El Hajj, F Jollivet, Y Kfoury, ... Blood, The Journal of the American Society of Hematology 125 (3), 474-482, 2015 | 84 | 2015 |
Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome Y Kfoury, N Setterblad, M El-Sabban, A Zamborlini, Z Dassouki, H El Hajj, ... Blood, The Journal of the American Society of Hematology 117 (1), 190-199, 2011 | 64 | 2011 |
Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease D Rohde, K Vandoorne, IH Lee, J Grune, S Zhang, CS McAlpine, ... Nature cardiovascular research 1 (1), 28-44, 2022 | 58 | 2022 |
Arsenic trioxide induces accumulation of cytotoxic levels of ceramide in acute promyelocytic leukemia and adult T-cell leukemia/lymphoma cells through de novo ceramide … GS Dbaibo, Y Kfoury, N Darwiche, S Panjarian, L Kozhaya, R Nasr, ... haematologica 92 (6), 753-762, 2007 | 58 | 2007 |
The multifaceted oncoprotein Tax: subcellular localization, posttranslational modifications, and NF-κB activation Y Kfoury, R Nasr, C Journo, R Mahieux, C Pique, A Bazarbachi Advances in cancer research 113, 85-120, 2012 | 57 | 2012 |
Proapoptotic regimes for HTLV-I-transformed cells: targeting Tax and the NF-κB pathway. Y Kfoury, R Nasr, O Hermine, A Bazarbachi Cell Death & Differentiation 12, 2005 | 53 | 2005 |
EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I–associated adult T-cell leukemia … G Moarbess, H El-Hajj, Y Kfoury, ME El-Sabban, Y Lepelletier, O Hermine, ... Blood, The Journal of the American Society of Hematology 111 (7), 3770-3777, 2008 | 48 | 2008 |