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Adrian Achuthan
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Defining GM-CSF–and macrophage-CSF–dependent macrophage responses by in vitro models
DC Lacey, A Achuthan, AJ Fleetwood, H Dinh, J Roiniotis, GM Scholz, ...
The Journal of Immunology 188 (11), 5752-5765, 2012
6622012
Colony stimulating factors and myeloid cell biology in health and disease
JA Hamilton, A Achuthan
Trends in immunology 34 (2), 81-89, 2013
3352013
Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry
YK Huang, M Wang, Y Sun, N Di Costanzo, C Mitchell, A Achuthan, ...
Nature communications 10 (1), 3928, 2019
2252019
Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles
AJ Fleetwood, MKS Lee, W Singleton, A Achuthan, MC Lee, ...
Frontiers in cellular and infection microbiology 7, 351, 2017
1742017
Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation
A Achuthan, AD Cook, MC Lee, R Saleh, HW Khiew, MWN Chang, ...
The Journal of clinical investigation 126 (9), 3453-3466, 2016
1642016
GM-CSF: a promising target in inflammation and autoimmunity
KMC Lee, AA Achuthan, JA Hamilton
ImmunoTargets and Therapy, 225-240, 2020
1052020
CCL17 blockade as a therapy for osteoarthritis pain and disease
MC Lee, R Saleh, A Achuthan, AJ Fleetwood, I Förster, JA Hamilton, ...
Arthritis research & therapy 20, 1-10, 2018
902018
Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity
A Achuthan, ASM Aslam, Q Nguyen, PY Lam, AJ Fleetwood, AT Frye, ...
Cell Death & Disease 9 (3), 267, 2018
682018
Urokinase plasminogen activator is a central regulator of macrophage three-dimensional invasion, matrix degradation, and adhesion
AJ Fleetwood, A Achuthan, H Schultz, A Nansen, K Almholt, P Usher, ...
The Journal of Immunology 192 (8), 3540-3547, 2014
662014
Autocrine IFN-I inhibits isocitrate dehydrogenase in the TCA cycle of LPS-stimulated macrophages
DP De Souza, A Achuthan, MKS Lee, KJ Binger, MC Lee, S Davidson, ...
The Journal of clinical investigation 129 (10), 4239-4244, 2019
652019
Epigenetic and transcriptional regulation of IL4-induced CCL17 production in human monocytes and murine macrophages
AT Hsu, TJ Lupancu, MC Lee, AJ Fleetwood, AD Cook, JA Hamilton, ...
Journal of Biological Chemistry 293 (29), 11415-11423, 2018
602018
IRF6 regulates the expression of IL-36γ by human oral epithelial cells in response to Porphyromonas gingivalis
J Huynh, GM Scholz, J Aw, MQ Kwa, A Achuthan, JA Hamilton, ...
The Journal of Immunology 196 (5), 2230-2238, 2016
592016
TNF and granulocyte macrophage-colony stimulating factor interdependence mediates inflammation via CCL17
AD Cook, MC Lee, R Saleh, HW Khiew, AD Christensen, A Achuthan, ...
JCI insight 3 (6), e99249, 2018
512018
Targeting GM-CSF in inflammatory and autoimmune disorders
AA Achuthan, KMC Lee, JA Hamilton
Seminars in immunology 54, 101523, 2021
462021
G-CSF receptor blockade ameliorates arthritic pain and disease
MC Lee, JA McCubbin, AD Christensen, DP Poole, P Rajasekhar, ...
The Journal of Immunology 198 (9), 3565-3575, 2017
432017
Targeting GM-CSF for collagenase-induced osteoarthritis pain and disease in mice
KMC Lee, V Prasad, A Achuthan, AJ Fleetwood, JA Hamilton, AD Cook
Osteoarthritis and Cartilage 28 (4), 486-491, 2020
402020
CCL17 in Inflammation and Pain
KMC Lee, A Jarnicki, A Achuthan, AJ Fleetwood, GP Anderson, C Ellson, ...
The Journal of Immunology 205 (1), 213-222, 2020
392020
CSF-1 in inflammatory and arthritic pain development
R Saleh, MC Lee, SH Khiew, C Louis, AJ Fleetwood, A Achuthan, ...
The Journal of Immunology 201 (7), 2042-2053, 2018
382018
GM-CSF–and IRF4-Dependent Signaling Can Regulate Myeloid Cell Numbers and the Macrophage Phenotype during Inflammation
MC Lee, DC Lacey, AJ Fleetwood, A Achuthan, JA Hamilton, AD Cook
The Journal of Immunology 202 (10), 3033-3040, 2019
342019
CCL17/TARC in autoimmunity and inflammation—not just a T‐cell chemokine
TJ Lupancu, M Eivazitork, JA Hamilton, AA Achuthan, KMC Lee
Immunology and Cell Biology 101 (7), 600-609, 2023
322023
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