| LUBAC-recruited CYLD and A20 regulate gene activation and cell death by exerting opposing effects on linear ubiquitin in signaling complexes P Draber, S Kupka, M Reichert, H Draberova, E Lafont, D de Miguel, ... Cell reports 13 (10), 2258-2272, 2015 | 307 | 2015 |
| Shedding light on the interaction between TMPyP4 and human telomeric quadruplexes L Martino, B Pagano, I Fotticchia, S Neidle, C Giancola The Journal of Physical Chemistry B 113 (44), 14779-14786, 2009 | 196 | 2009 |
| Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d (TGGGGT)] 4 L Martino, A Virno, B Pagano, A Virgilio, S Di Micco, A Galeone, ... Journal of the American Chemical Society 129 (51), 16048-16056, 2007 | 194 | 2007 |
| Stability and binding properties of a modified thrombin binding aptamer B Pagano, L Martino, A Randazzo, C Giancola Biophysical journal 94 (2), 562-569, 2008 | 178 | 2008 |
| La-related protein 4 binds poly (A), interacts with the poly (A)-binding protein MLLE domain via a variant PAM2w motif, and can promote mRNA stability R Yang, SA Gaidamakov, J Xie, J Lee, L Martino, G Kozlov, AK Crawford, ... Molecular and cellular biology, 2011 | 156 | 2011 |
| SPATA2-mediated binding of CYLD to HOIP enables CYLD recruitment to signaling complexes S Kupka, D De Miguel, P Draber, L Martino, S Surinova, K Rittinger, ... Cell reports 16 (9), 2271-2280, 2016 | 145 | 2016 |
| Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1 GF De Nicola, ED Martin, A Chaikuad, R Bassi, J Clark, L Martino, ... Nature structural & molecular biology 20 (10), 1182-1190, 2013 | 133 | 2013 |
| Fragment-based covalent ligand screening enables rapid discovery of inhibitors for the RBR E3 ubiquitin ligase HOIP H Johansson, YC Isabella Tsai, K Fantom, CW Chung, S Kümper, ... Journal of the American Chemical Society 141 (6), 2703-2712, 2019 | 125 | 2019 |
| A new modified thrombin binding aptamer containing a 5′–5′ inversion of polarity site L Martino, A Virno, A Randazzo, A Virgilio, V Esposito, C Giancola, ... Nucleic acids research 34 (22), 6653-6662, 2006 | 114 | 2006 |
| Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module L Martino, S Pennell, G Kelly, B Busi, P Brown, RA Atkinson, ... Nucleic acids research 43 (1), 645-660, 2015 | 76 | 2015 |
| The association of a La module with the PABP-interacting motif PAM2 is a recurrent evolutionary process that led to the neofunctionalization of La-related proteins R Merret, L Martino, C Bousquet-Antonelli, S Fneich, J Descombin, ... Rna 19 (1), 36-50, 2013 | 67 | 2013 |
| Analysis of the interaction with the hepatitis C virus mRNA reveals an alternative mode of RNA recognition by the human La protein L Martino, S Pennell, G Kelly, TTT Bui, O Kotik-Kogan, SJ Smerdon, ... Nucleic acids research 40 (3), 1381-1394, 2012 | 65 | 2012 |
| The interaction of the Escherichia coli protein SlyD with nickel ions illuminates the mechanism of regulation of its peptidyl‐prolyl isomerase activity L Martino, Y He, KLD Hands‐Taylor, ER Valentine, G Kelly, C Giancola, ... The FEBS journal 276 (16), 4529-4544, 2009 | 65 | 2009 |
| Structural studies of HHARI/UbcH7∼ Ub reveal unique E2∼ Ub conformational restriction by RBR RING1 KK Dove, JL Olszewski, L Martino, DM Duda, XS Wu, DJ Miller, KH Reiter, ... Structure 25 (6), 890-900. e5, 2017 | 62 | 2017 |
| Synthesis, biophysical characterization, and anti-HIV activity of glyco-conjugated G-quadruplex-forming oligonucleotides J D’Onofrio, L Petraccone, L Martino, GD Fabio, A Iadonisi, J Balzarini, ... Bioconjugate chemistry 19 (3), 607-616, 2008 | 57 | 2008 |
| Structural basis for the glycosyltransferase activity of the Salmonella effector SseK3 D Esposito, RA Günster, L Martino, K El Omari, A Wagner, TLM Thurston, ... Journal of Biological Chemistry 293 (14), 5064-5078, 2018 | 54 | 2018 |
| 5'-Modified G-quadruplex forming oligonucleotides endowed with anti-HIV activity: Synthesis and biophysical properties J D'Onofrio, L Petraccone, E Erra, L Martino, G Di Fabio, L De Napoli, ... Bioconjugate chemistry 18 (4), 1194-1204, 2007 | 51 | 2007 |
| Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA KLD Hands-Taylor, L Martino, R Tata, JJ Babon, TT Bui, AF Drake, ... Nucleic acids research 38 (12), 4052-4066, 2010 | 43 | 2010 |
| Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures V Esposito, L Martino, G Citarella, A Virgilio, L Mayol, C Giancola, ... Nucleic acids research 38 (6), 2069-2080, 2010 | 43 | 2010 |
| LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA I Cruz-Gallardo, L Martino, G Kelly, RA Atkinson, R Trotta, S De Tito, ... Nucleic acids research 47 (8), 4272-4291, 2019 | 41 | 2019 |
Concetta GiancolaFull Professor of Physical Chemistry, University of Naples Federico IIVerificeret mail på unina.it