BAG‐1 modulates the chaperone activity of Hsp70/Hsc70 S Takayama, DN Bimston, S Matsuzawa, BC Freeman, C Aime‐Sempe, ... The EMBO journal, 1997 | 627 | 1997 |
The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj‐1 have distinct roles in recognition of a non‐native protein and protein refolding. BC Freeman, RI Morimoto The EMBO journal 15 (12), 2969-2979, 1996 | 601 | 1996 |
Identification of a regulatory motif in Hsp70 that affects ATPase activity, substrate binding and interaction with HDJ‐1. BC Freeman, MP Myers, R Schumacher, RI Morimoto The EMBO journal 14 (10), 2281-2292, 1995 | 570 | 1995 |
Disassembly of transcriptional regulatory complexes by molecular chaperones BC Freeman, KR Yamamoto Science 296 (5576), 2232-2235, 2002 | 534 | 2002 |
Molecular chaperone machines: chaperone activities of the cyclophilin Cyp-40 and the steroid aporeceptor-associated protein p23 BC Freeman, DO Toft, RI Morimoto Science 274 (5293), 1718-1720, 1996 | 442 | 1996 |
Cdc37 is a molecular chaperone with specific functions in signal transduction. Y Kimura, SL Rutherford, Y Miyata, I Yahara, BC Freeman, L Yue, ... Genes & Development 11 (14), 1775-1785, 1997 | 263 | 1997 |
Cloning and Subcellular Localization of Human Mitochondrial hsp70 (∗) T Bhattacharyya, AN Karnezis, SP Murphy, T Hoang, BC Freeman, ... Journal of Biological Chemistry 270 (4), 1705-1710, 1995 | 251 | 1995 |
The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies BC Freeman, SJ Felts, DO Toft, KR Yamamoto Genes & Development 14 (4), 422-434, 2000 | 244 | 2000 |
Cooperative action of Hsp70, Hsp90, and DnaJ proteins in protein renaturation RJ Schumacher, WJ Hansen, BC Freeman, E Alnemri, G Litwack, DO Toft Biochemistry 35 (47), 14889-14898, 1996 | 214 | 1996 |
Slowing bacterial translation speed enhances eukaryotic protein folding efficiency E Siller, DC DeZwaan, JF Anderson, BC Freeman, JM Barral Journal of Molecular Biology 396 (5), 1310-1318, 2010 | 204 | 2010 |
Human Hsp70 molecular chaperone binds two calcium ions within the ATPase domain M Sriram, J Osipiuk, BC Freeman, RI Morimoto, A Joachimiak Structure 5 (3), 403-414, 1997 | 196 | 1997 |
A WD-repeat protein stabilizes ORC binding to chromatin Z Shen, KM Sathyan, Y Geng, R Zheng, A Chakraborty, B Freeman, ... Molecular Cell 40 (1), 99-111, 2010 | 152 | 2010 |
The molecular chaperone hsp40 regulates the activity of P58IPK, the cellular inhibitor of PKR MW Melville, WJ Hansen, BC Freeman, WJ Welch, MG Katze Proceedings of the National Academy of Sciences 94 (1), 97-102, 1997 | 132 | 1997 |
The hsp90 molecular chaperone modulates multiple telomerase activities OA Toogun, DC DeZwaan, BC Freeman Molecular and Cellular Biology 28 (1), 457-467, 2008 | 117 | 2008 |
Continuous recycling: a mechanism for modulatory signal transduction BC Freeman, KR Yamamoto Trends in Biochemical Sciences 26 (5), 285-290, 2001 | 111 | 2001 |
HSP90: the Rosetta stone for cellular protein dynamics? DC DeZwaan, BC Freeman Cell Cycle 7 (8), 1006-1012, 2008 | 107 | 2008 |
p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity F Forafonov, OA Toogun, I Grad, E Suslova, BC Freeman, D Picard Molecular and Cellular Biology 28 (10), 3446-3456, 2008 | 105 | 2008 |
Global functional map of the p23 molecular chaperone reveals an extensive cellular network FJ Echtenkamp, E Zelin, E Oxelmark, JI Woo, BJ Andrews, M Garabedian, ... Molecular Cell 43 (2), 229-241, 2011 | 102 | 2011 |
Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α J Sun, Y Yang, K Wan, N Mao, TY Yu, YC Lin, DC DeZwaan, BC Freeman, ... Cell Research 21 (2), 258-274, 2010 | 97 | 2010 |
The p23 molecular chaperone promotes functional telomerase complexes through DNA dissociation OA Toogun, W Zeiger, BC Freeman Proceedings of the National Academy of Sciences 104 (14), 5765-5770, 2007 | 69 | 2007 |