Følg
Michael D. Bartberger
Michael D. Bartberger
Senior Vice President, Computational Chemistry, Alterome Therapeutics
Verificeret mail på alterome.com - Startside
Titel
Citeret af
Citeret af
År
A survey of the role of noncovalent sulfur interactions in drug design
BR Beno, KS Yeung, MD Bartberger, LD Pennington, NA Meanwell
Journal of medicinal chemistry 58 (11), 4383-4438, 2015
7102015
Anion− aromatic bonding: a case for anion recognition by π-acidic rings
M Mascal, A Armstrong, MD Bartberger
Journal of the American Chemical Society 124 (22), 6274-6276, 2002
6942002
Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors
BA Lanman, JR Allen, JG Allen, AK Amegadzie, KS Ashton, SK Booker, ...
Journal of medicinal chemistry 63 (1), 52-65, 2019
6102019
The reduction potential of nitric oxide (NO) and its importance to NO biochemistry
MD Bartberger, W Liu, E Ford, KM Miranda, C Switzer, JM Fukuto, ...
Proceedings of the National Academy of Sciences 99 (17), 10958-10963, 2002
4392002
A standard set of pericyclic reactions of hydrocarbons for the benchmarking of computational methods: the performance of ab initio, density functional, CASSCF, CASPT2, and CBS …
V Guner, KS Khuong, AG Leach, PS Lee, MD Bartberger, KN Houk
The Journal of Physical Chemistry A 107 (51), 11445-11459, 2003
4182003
Discovery of AMG 232, a potent, selective, and orally bioavailable MDM2–p53 inhibitor in clinical development
D Sun, Z Li, Y Rew, M Gribble, MD Bartberger, HP Beck, J Canon, A Chen, ...
Journal of medicinal chemistry 57 (4), 1454-1472, 2014
3432014
A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system
KM Miranda, N Paolocci, T Katori, DD Thomas, E Ford, MD Bartberger, ...
Proceedings of the National Academy of Sciences 100 (16), 9196-9201, 2003
3272003
Insertion of helium and molecular hydrogen through the orifice of an open fullerene
Y Rubin, T Jarrosson, GW Wang, MD Bartberger, KN Houk, G Schick, ...
Angewandte Chemie 113 (8), 1591-1594, 2001
3092001
The magnitude of [C− H⊙⊙⊙ O] hydrogen bonding in molecular and supramolecular assemblies
FM Raymo, MD Bartberger, KN Houk, JF Stoddart
Journal of the American Chemical Society 123 (38), 9264-9267, 2001
2752001
The physiological chemistry and biological activity of nitroxyl (HNO): the neglected, misunderstood, and enigmatic nitrogen oxide
JM Fukuto, MD Bartberger, AS Dutton, N Paolocci, DA Wink, KN Houk
Chemical research in toxicology 18 (5), 790-801, 2005
2382005
On the acidity and reactivity of HNO in aqueous solution and biological systems
MD Bartberger, JM Fukuto, KN Houk
Proceedings of the National Academy of Sciences 98 (5), 2194-2198, 2001
2162001
Structure-based design of novel inhibitors of the MDM2–p53 interaction
Y Rew, D Sun, F Gonzalez-Lopez De Turiso, MD Bartberger, HP Beck, ...
Journal of medicinal chemistry 55 (11), 4936-4954, 2012
2042012
Discovery and optimization of chromenotriazolopyrimidines as potent inhibitors of the mouse double minute 2− tumor protein 53 protein− protein interaction
JG Allen, MP Bourbeau, GE Wohlhieter, MD Bartberger, K Michelsen, ...
Journal of Medicinal Chemistry 52 (22), 7044-7053, 2009
1952009
S−N Dissociation Energies of S-Nitrosothiols:  On the Origins of Nitrosothiol Decomposition Rates
MD Bartberger, JD Mannion, SC Powell, JS Stamler, KN Houk, EJ Toone
Journal of the American Chemical Society 123 (36), 8868-8869, 2001
1632001
From fragment screening to in vivo efficacy: optimization of a series of 2-aminoquinolines as potent inhibitors of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)
Y Cheng, TC Judd, MD Bartberger, J Brown, K Chen, RT Fremeau Jr, ...
Journal of medicinal chemistry 54 (16), 5836-5857, 2011
1612011
Photophysics of π-conjugated polymers that incorporate metal to ligand charge transfer chromophores
KD Ley, CE Whittle, MD Bartberger, KS Schanze
Journal of the American Chemical Society 119 (14), 3423-3424, 1997
1601997
Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins: a chemical discussion of the differential biological effects of these redox related products of NOS
KM Miranda, RW Nims, DD Thomas, MG Espey, D Citrin, MD Bartberger, ...
Journal of inorganic biochemistry 93 (1-2), 52-60, 2003
1542003
Systematic Study of the Glutathione (GSH) Reactivity of N-Arylacrylamides: 1. Effects of Aryl Substitution
VJ Cee, LP Volak, Y Chen, MD Bartberger, C Tegley, T Arvedson, ...
Journal of Medicinal Chemistry 58 (23), 9171-9178, 2015
1422015
Theory, spectroscopy, and crystallographic analysis of S-nitrosothiols: conformational distribution dictates spectroscopic behavior
MD Bartberger, KN Houk, SC Powell, JD Mannion, KY Lo, JS Stamler, ...
Journal of the American Chemical Society 122 (24), 5889-5890, 2000
1412000
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors
DJ Lloyd, DJ St Jean Jr, RJM Kurzeja, RC Wahl, K Michelsen, R Cupples, ...
Nature 504 (7480), 437-440, 2013
1132013
Systemet kan ikke foretage handlingen nu. Prøv igen senere.
Artikler 1–20