TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD MA White, E Kim, A Duffy, R Adalbert, BU Phillips, OM Peters, ... Nature neuroscience 21 (4), 552-563, 2018 | 260 | 2018 |
Basal forebrain and brainstem cholinergic neurons differentially impact amygdala circuits and learning-related behavior T Aitta-Aho, YA Hay, BU Phillips, LM Saksida, TJ Bussey, O Paulsen, ... Current Biology 28 (16), 2557-2569. e4, 2018 | 79 | 2018 |
Measuring motivation and reward‐related decision making in the rodent operant touchscreen system CJ Heath, BU Phillips, TJ Bussey, LM Saksida Current protocols in neuroscience 74 (1), 8.34. 1-8.34. 20, 2016 | 50 | 2016 |
Dopamine D2-like receptor stimulation blocks negative feedback in visual and spatial reversal learning in the rat: behavioural and computational evidence J Alsiö, BU Phillips, J Sala-Bayo, SRO Nilsson, TC Calafat-Pla, ... Psychopharmacology 236, 2307-2323, 2019 | 42 | 2019 |
Optimisation of cognitive performance in rodent operant (touchscreen) testing: evaluation and effects of reinforcer strength BU Phillips, CJ Heath, Z Ossowska, TJ Bussey, LM Saksida Learning & Behavior 45, 252-262, 2017 | 38 | 2017 |
A touchscreen motivation assessment evaluated in Huntington's disease patients and R6/1 model mice CJ Heath, C O'Callaghan, SL Mason, BU Phillips, LM Saksida, ... Frontiers in Neurology 10, 858, 2019 | 36 | 2019 |
Selective effects of 5-HT2C receptor modulation on performance of a novel valence-probe visual discrimination task and probabilistic reversal learning in mice BU Phillips, S Dewan, SRO Nilsson, TW Robbins, CJ Heath, LM Saksida, ... Psychopharmacology 235, 2101-2111, 2018 | 36 | 2018 |
Optimizing reproducibility of operant testing through reinforcer standardization: identification of key nutritional constituents determining reward strength in touchscreens EW Kim, BU Phillips, CJ Heath, SY Cho, H Kim, J Sreedharan, HT Song, ... Molecular brain 10, 1-10, 2017 | 33 | 2017 |
Accumbal cholinergic interneurons differentially influence motivation related to satiety signaling T Aitta-Aho, BU Phillips, E Pappa, YA Hay, F Harnischfeger, CJ Heath, ... Eneuro 4 (2), 2017 | 28 | 2017 |
Assessment of mGluR5 KO mice under conditions of low stress using a rodent touchscreen apparatus reveals impaired behavioural flexibility driven by perseverative responses J Lim, E Kim, HJ Noh, S Kang, BU Phillips, DG Kim, TJ Bussey, L Saksida, ... Molecular brain 12, 1-13, 2019 | 27 | 2019 |
Blockade of muscarinic acetylcholine receptors facilitates motivated behaviour and rescues a model of antipsychotic-induced amotivation JM Hailwood, CJ Heath, BU Phillips, TW Robbins, LM Saksida, TJ Bussey Neuropsychopharmacology 44 (6), 1068-1075, 2019 | 21 | 2019 |
Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice JE Lewis, ORM Woodward, D Nuzzaci, CA Smith, AE Adriaenssens, ... Molecular metabolism 66, 101604, 2022 | 18 | 2022 |
Translational approaches to evaluating motivation in laboratory rodents: conventional and touchscreen-based procedures BU Phillips, L Lopez-Cruz, J Hailwood, CJ Heath, LM Saksida, TJ Bussey Current Opinion in Behavioral Sciences 22, 21-27, 2018 | 17 | 2018 |
Reconsidering repurposing: long-term metformin treatment impairs cognition in Alzheimer’s model mice SY Cho, EW Kim, SJ Park, BU Phillips, J Jeong, H Kim, CJ Heath, D Kim, ... Translational psychiatry 14 (1), 34, 2024 | 15 | 2024 |
Statistical simulations show that scientists need not increase overall sample size by default when including both sexes in in vivo studies B Phillips, TN Haschler, NA Karp PLoS Biology 21 (6), e3002129, 2023 | 13 | 2023 |
Retrospective analysis of the potential use of virtual control groups in preclinical toxicity assessment using the eTOX database PSR Wright, GF Smith, KA Briggs, R Thomas, G Maglennon, P Mikulskis, ... Regulatory Toxicology and Pharmacology 138, 105309, 2023 | 13 | 2023 |
The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment EL Hardaker, E Sanseviero, A Karmokar, D Taylor, M Milo, C Michaloglou, ... Nature Communications 15 (1), 1700, 2024 | 12 | 2024 |
Comparable roles for serotonin in rats and humans for computations underlying flexible decision-making Q Luo, JW Kanen, A Bari, N Skandali, C Langley, GM Knudsen, J Alsiö, ... Neuropsychopharmacology 49 (3), 600-608, 2024 | 12 | 2024 |
Coexistence of perseveration and apathy in the TDP-43Q331K knock-in mouse model of ALS–FTD E Kim, MA White, BU Phillips, L Lopez-Cruz, H Kim, CJ Heath, JE Lee, ... Translational psychiatry 10 (1), 377, 2020 | 12 | 2020 |
Translational tests involving non-reward: methodological considerations BU Phillips, L Lopez-Cruz, LM Saksida, TJ Bussey Psychopharmacology 236 (1), 449-461, 2019 | 12 | 2019 |