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Areej Abuhammad
Areej Abuhammad
Department of Pharmaceutical Sciences Faculty of Pharmacy University of Jordan
Verificeret mail på ju.edu.jo - Startside
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Arylamine N‐acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery
E Sim, A Abuhammad, A Ryan
British Journal of Pharmacology 171 (11), 2705-2725, 2014
1682014
Pharmacophore Modeling, Quantitative Structure−Activity Relationship Analysis, and Shape-Complemented in Silico Screening Allow Access to Novel Influenza …
AM Abu Hammad, MO Taha
Journal of chemical information and modeling 49 (4), 978-996, 2009
732009
Cholesterol metabolism: a potential therapeutic target in Mycobacteria
A Abuhammad
British journal of pharmacology 174 (14), 2194-2208, 2017
432017
QSAR studies in the discovery of novel type-II diabetic therapies
A Abuhammad, MO Taha
Expert opinion on drug discovery 11 (2), 197-214, 2016
412016
Identifying the characteristics of virtual reality gamification for complex educational topics
J Falah, M Wedyan, SFM Alfalah, M Abu-Tarboush, A Al-Jakheem, ...
Multimodal Technologies and Interaction 5 (9), 53, 2021
392021
Structure of arylamine N-acetyltransferase from Mycobacterium tuberculosis determined by cross-seeding with the homologous protein from M. marinum: triumph over adversity
A Abuhammad, ED Lowe, MA McDonough, PD Shaw Stewart, SA Kolek, ...
Biological Crystallography 69 (8), 1433-1446, 2013
392013
Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide
CJ Wang, N Laurieri, A Abuhammad, E Lowe, I Westwood, A Ryan, E Sim
Structural Biology and Crystallization Communications 66 (1), 2-7, 2010
392010
Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: An essential enzyme for mycobacterial survival inside macrophages
A Abuhammad, E Fullam, ED Lowe, D Staunton, A Kawamura, ...
PLoS One 7 (12), e52790, 2012
372012
Design, synthesis and structure–activity relationships of 3, 5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase
E Fullam, J Talbot, A Abuhammed, I Westwood, SG Davies, AJ Russell, ...
Bioorganic & medicinal chemistry letters 23 (9), 2759-2764, 2013
352013
“MedChemVR”: A virtual reality game to enhance medicinal chemistry education
A Abuhammad, J Falah, SFM Alfalah, M Abu-Tarboush, RT Tarawneh, ...
Multimodal Technologies and Interaction 5 (3), 10, 2021
322021
Combining docking, scoring and molecular field analyses to probe influenza neuraminidase–ligand interactions
AMA Hammad, FU Afifi, MO Taha
Journal of Molecular Graphics and Modelling 26 (2), 443-456, 2007
312007
Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site
AM Abuhammad, ED Lowe, E Fullam, M Noble, EF Garman, E Sim
Protein & cell 1 (4), 384-392, 2010
302010
Analysis of β-amino alcohols as inhibitors of the potential anti-tubercular target N-acetyltransferase
E Fullam, A Abuhammad, DL Wilson, MC Anderton, SG Davies, ...
Bioorganic & medicinal chemistry letters 21 (4), 1185-1190, 2011
272011
Comparison of the Arylamine N-Acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis
E Fullam, A Kawamura, H Wilkinson, A Abuhammad, I Westwood, E Sim
The protein journal 28, 281-293, 2009
262009
Computational modeling of the bat HKU4 coronavirus 3CLpro inhibitors as a tool for the development of antivirals against the emerging Middle East respiratory …
A Abuhammad, RA Al‐Aqtash, BJ Anson, AD Mesecar, MO Taha
Journal of Molecular Recognition 30 (11), e2644, 2017
252017
Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti‐tubercular agents using a fragment‐based drug design approach
A Ryan, E Polycarpou, NA Lack, D Evangelopoulos, C Sieg, A Halman, ...
British journal of pharmacology 174 (14), 2209-2224, 2017
222017
Innovative computer-aided methods for the discovery of new kinase ligands
A Abuhammad, M Taha
Future medicinal chemistry 8 (5), 509-526, 2016
222016
Exploration of piperidinols as potential antitubercular agents
A Abuhammad, E Fullam, S Bhakta, AJ Russell, GM Morris, PW Finn, ...
Molecules 19 (10), 16274-16290, 2014
202014
Improvement of the expression and purification of Mycobacterium tuberculosis arylamine N-acetyltransferase (TBNAT) a potential target for novel anti-tubercular agents
A Abuhammad, N Lack, J Schweichler, D Staunton, RB Sim, E Sim
Protein Expression and Purification 80 (2), 246-252, 2011
202011
Homology modeling of MCH1 receptor and validation by docking/scoring and protein-aligned CoMFA
A Abu-Hammad, WA Zalloum, H Zalloum, G Abu-Sheikha, MO Taha
European journal of medicinal chemistry 44 (6), 2583-2596, 2009
162009
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