Arylamine N‐acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery E Sim, A Abuhammad, A Ryan British Journal of Pharmacology 171 (11), 2705-2725, 2014 | 168 | 2014 |
Pharmacophore Modeling, Quantitative Structure−Activity Relationship Analysis, and Shape-Complemented in Silico Screening Allow Access to Novel Influenza … AM Abu Hammad, MO Taha Journal of chemical information and modeling 49 (4), 978-996, 2009 | 73 | 2009 |
Cholesterol metabolism: a potential therapeutic target in Mycobacteria A Abuhammad British journal of pharmacology 174 (14), 2194-2208, 2017 | 43 | 2017 |
QSAR studies in the discovery of novel type-II diabetic therapies A Abuhammad, MO Taha Expert opinion on drug discovery 11 (2), 197-214, 2016 | 41 | 2016 |
Identifying the characteristics of virtual reality gamification for complex educational topics J Falah, M Wedyan, SFM Alfalah, M Abu-Tarboush, A Al-Jakheem, ... Multimodal Technologies and Interaction 5 (9), 53, 2021 | 39 | 2021 |
Structure of arylamine N-acetyltransferase from Mycobacterium tuberculosis determined by cross-seeding with the homologous protein from M. marinum: triumph over adversity A Abuhammad, ED Lowe, MA McDonough, PD Shaw Stewart, SA Kolek, ... Biological Crystallography 69 (8), 1433-1446, 2013 | 39 | 2013 |
Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide CJ Wang, N Laurieri, A Abuhammad, E Lowe, I Westwood, A Ryan, E Sim Structural Biology and Crystallization Communications 66 (1), 2-7, 2010 | 39 | 2010 |
Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: An essential enzyme for mycobacterial survival inside macrophages A Abuhammad, E Fullam, ED Lowe, D Staunton, A Kawamura, ... PLoS One 7 (12), e52790, 2012 | 37 | 2012 |
Design, synthesis and structure–activity relationships of 3, 5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase E Fullam, J Talbot, A Abuhammed, I Westwood, SG Davies, AJ Russell, ... Bioorganic & medicinal chemistry letters 23 (9), 2759-2764, 2013 | 35 | 2013 |
“MedChemVR”: A virtual reality game to enhance medicinal chemistry education A Abuhammad, J Falah, SFM Alfalah, M Abu-Tarboush, RT Tarawneh, ... Multimodal Technologies and Interaction 5 (3), 10, 2021 | 32 | 2021 |
Combining docking, scoring and molecular field analyses to probe influenza neuraminidase–ligand interactions AMA Hammad, FU Afifi, MO Taha Journal of Molecular Graphics and Modelling 26 (2), 443-456, 2007 | 31 | 2007 |
Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site AM Abuhammad, ED Lowe, E Fullam, M Noble, EF Garman, E Sim Protein & cell 1 (4), 384-392, 2010 | 30 | 2010 |
Analysis of β-amino alcohols as inhibitors of the potential anti-tubercular target N-acetyltransferase E Fullam, A Abuhammad, DL Wilson, MC Anderton, SG Davies, ... Bioorganic & medicinal chemistry letters 21 (4), 1185-1190, 2011 | 27 | 2011 |
Comparison of the Arylamine N-Acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis E Fullam, A Kawamura, H Wilkinson, A Abuhammad, I Westwood, E Sim The protein journal 28, 281-293, 2009 | 26 | 2009 |
Computational modeling of the bat HKU4 coronavirus 3CLpro inhibitors as a tool for the development of antivirals against the emerging Middle East respiratory … A Abuhammad, RA Al‐Aqtash, BJ Anson, AD Mesecar, MO Taha Journal of Molecular Recognition 30 (11), e2644, 2017 | 25 | 2017 |
Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti‐tubercular agents using a fragment‐based drug design approach A Ryan, E Polycarpou, NA Lack, D Evangelopoulos, C Sieg, A Halman, ... British journal of pharmacology 174 (14), 2209-2224, 2017 | 22 | 2017 |
Innovative computer-aided methods for the discovery of new kinase ligands A Abuhammad, M Taha Future medicinal chemistry 8 (5), 509-526, 2016 | 22 | 2016 |
Exploration of piperidinols as potential antitubercular agents A Abuhammad, E Fullam, S Bhakta, AJ Russell, GM Morris, PW Finn, ... Molecules 19 (10), 16274-16290, 2014 | 20 | 2014 |
Improvement of the expression and purification of Mycobacterium tuberculosis arylamine N-acetyltransferase (TBNAT) a potential target for novel anti-tubercular agents A Abuhammad, N Lack, J Schweichler, D Staunton, RB Sim, E Sim Protein Expression and Purification 80 (2), 246-252, 2011 | 20 | 2011 |
Homology modeling of MCH1 receptor and validation by docking/scoring and protein-aligned CoMFA A Abu-Hammad, WA Zalloum, H Zalloum, G Abu-Sheikha, MO Taha European journal of medicinal chemistry 44 (6), 2583-2596, 2009 | 16 | 2009 |