Artikler med krav om offentlig adgang - Jing ZengFå flere oplysninger
Tilgængelige et sted: 23
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
MF Richter, KT Zhao, E Eton, A Lapinaite, GA Newby, BW Thuronyi, ...
Nature biotechnology 38 (7), 883-891, 2020
Krav: US National Science Foundation, Bill & Melinda Gates Foundation, US National …
Highly efficient therapeutic gene editing of human hematopoietic stem cells
Y Wu, J Zeng, BP Roscoe, P Liu, Q Yao, CR Lazzarotto, K Clement, ...
Nature medicine 25 (5), 776-783, 2019
Krav: US National Institutes of Health, Doris Duke Charitable Foundation
An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities
JM Gehrke, O Cervantes, MK Clement, Y Wu, J Zeng, DE Bauer, L Pinello, ...
Nature biotechnology 36 (10), 977-982, 2018
Krav: US National Science Foundation, US National Institutes of Health
Therapeutic base editing of human hematopoietic stem cells
J Zeng, Y Wu, C Ren, J Bonanno, AH Shen, D Shea, JM Gehrke, ...
Nature Medicine 26 (4), 535-541, 2020
Krav: US National Institutes of Health
Genome editing of HBG1 and HBG2 to induce fetal hemoglobin
JY Métais, PA Doerfler, T Mayuranathan, DE Bauer, SC Fowler, MM Hsieh, ...
Blood advances 3 (21), 3379-3392, 2019
Krav: US National Institutes of Health, Doris Duke Charitable Foundation
Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci
MC Canver, S Lessard, L Pinello, Y Wu, Y Ilboudo, EN Stern, ...
Nature genetics 49 (4), 625-634, 2017
Krav: US National Institutes of Health, Howard Hughes Medical Institute, Canadian …
Editing aberrant splice sites efficiently restores β-globin expression in β-thalassemia
S Xu, K Luk, Q Yao, AH Shen, J Zeng, Y Wu, HY Luo, C Brendel, L Pinello, ...
Blood, The Journal of the American Society of Hematology 133 (21), 2255-2262, 2019
Krav: US National Institutes of Health, Doris Duke Charitable Foundation
Small-molecule PAPD5 inhibitors restore telomerase activity in patient stem cells
N Nagpal, J Wang, J Zeng, E Lo, DH Moon, K Luk, RO Braun, ...
Cell Stem Cell 26 (6), 896-909. e8, 2020
Krav: US Department of Defense, US National Institutes of Health
Human genetic diversity alters off-target outcomes of therapeutic gene editing
S Cancellieri, J Zeng, LY Lin, M Tognon, MA Nguyen, J Lin, N Bombieri, ...
Nature genetics 55 (1), 34-43, 2023
Krav: US National Institutes of Health, Doris Duke Charitable Foundation
BCL11A enhancer–edited hematopoietic stem cells persist in rhesus monkeys without toxicity
S Demirci, J Zeng, Y Wu, N Uchida, AH Shen, D Pellin, J Gamer, ...
The Journal of clinical investigation 130 (12), 6677-6687, 2020
Krav: US National Institutes of Health
ZNF410 represses fetal globin by singular control of CHD4
DS Vinjamur, Q Yao, MA Cole, C McGuckin, C Ren, J Zeng, M Hossain, ...
Nature genetics 53 (5), 719-728, 2021
Krav: US National Institutes of Health
Epitope editing enables targeted immunotherapy of acute myeloid leukaemia
G Casirati, A Cosentino, A Mucci, M Salah Mahmoud, I Ugarte Zabala, ...
Nature 621 (7978), 404-414, 2023
Krav: US National Institutes of Health
Dissecting ELANE neutropenia pathogenicity by human HSC gene editing
S Rao, Y Yao, JS de Brito, Q Yao, AH Shen, RE Watkinson, AL Kennedy, ...
Cell Stem Cell 28 (5), 833-845. e5, 2021
Krav: US National Institutes of Health
Optimization of nuclear localization signal composition improves CRISPR-cas12a editing rates in human primary cells
K Luk, P Liu, J Zeng, Y Wang, SA Maitland, F Idrizi, K Ponnienselvan, ...
GEN biotechnology 1 (3), 271-284, 2022
Krav: US National Institutes of Health, Doris Duke Charitable Foundation
Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells
J Zeng, MA Nguyen, P Liu, LF Da Silva, S Levesque, LY Lin, DG Justus, ...
Cell Stem Cell, 2023
Krav: US Department of Defense, US National Institutes of Health, Howard Hughes …
Pre-existing immunity does not impair the engraftment of CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation
K Essawi, W Hakami, MBN Khan, R Martin, J Zeng, R Chu, N Uchida, ...
Molecular Therapy Methods & Clinical Development 29, 483-493, 2023
Krav: US National Institutes of Health
Base editing of human hematopoietic stem cells
J Zeng, G Casirati, MA Nguyen, P Genovese, DE Bauer
Base Editors: Methods and Protocols, 43-62, 2023
Krav: US National Institutes of Health, Doris Duke Charitable Foundation
Human genetic diversity modifies therapeutic gene editing off-target potential
S Cancellieri, J Zeng, LY Lin, F Masillo, A Nguyen, N Bombieri, ...
bioRxiv, 2021
Krav: US National Institutes of Health
Human genetic diversity alters therapeutic gene editing off-target outcomes
S Cancellieri, J Zeng, LY Lin, M Tognon, MA Nguyen, J Lin, N Bombieri, ...
bioRxiv, 2021.05. 20.445054, 2021
Krav: US National Institutes of Health
CRISPR-Cas9 Genome Editing of γ-Globin Promoters in Human Hematopoietic Stem Cells to Induce Erythrocyte Fetal Hemoglobin for Treatment of β-Hemoglobinopathies
JY Metais, PA Doerfler, T Mayuranathan, DE Bauer, S Fowler, M Hsieh, ...
Blood 134, 2066, 2019
Krav: Doris Duke Charitable Foundation
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