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Timothy R. Crother
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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
K Shimada, TR Crother, J Karlin, J Dagvadorj, N Chiba, S Chen, ...
Immunity 36 (3), 401-414, 2012
21832012
Immunological consequences of intestinal fungal dysbiosis
ML Wheeler, JJ Limon, AS Bar, CA Leal, M Gargus, J Tang, J Brown, ...
Cell host & microbe 19 (6), 865-873, 2016
4162016
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation
H Xian, Y Liu, AR Nilsson, R Gatchalian, TR Crother, WG Tourtellotte, ...
Immunity 54 (7), 1463-1477. e11, 2021
2812021
Interleukin-1β is crucial for the induction of coronary artery inflammation in a mouse model of Kawasaki disease
Y Lee, DJ Schulte, K Shimada, S Chen, TR Crother, N Chiba, ...
Circulation 125 (12), 1542-1550, 2012
2282012
Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer
EL Lowe, TR Crother, S Rabizadeh, B Hu, H Wang, S Chen, K Shimada, ...
PloS one 5 (9), e13027, 2010
1882010
The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection
K Shimada, S Chen, PW Dempsey, R Sorrentino, R Alsabeh, ...
PLoS pathogens 5 (4), e1000379, 2009
1782009
Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis
G Tumurkhuu, K Shimada, J Dagvadorj, TR Crother, W Zhang, ...
Circulation research 119 (6), e76-e90, 2016
1682016
IL-17A is proatherogenic in high-fat diet-induced and Chlamydia pneumoniae infection-accelerated atherosclerosis in mice
S Chen, K Shimada, W Zhang, G Huang, TR Crother, M Arditi
The Journal of Immunology 185 (9), 5619-5627, 2010
1452010
Emerging role of IL-17 in atherosclerosis
S Chen, TR Crother, M Arditi
Journal of innate immunity 2 (4), 325-333, 2010
1442010
Lipopolysaccharide induces alveolar macrophage necrosis via CD14 and the P2X7 receptor leading to interleukin-1α release
J Dagvadorj, K Shimada, S Chen, HD Jones, G Tumurkhuu, W Zhang, ...
Immunity 42 (4), 640-653, 2015
1412015
The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury
HD Jones, TR Crother, RA Gonzalez-Villalobos, M Jupelli, S Chen, ...
American journal of respiratory cell and molecular biology 50 (2), 270-280, 2014
1362014
Intestinal permeability and IgA provoke immune vasculitis linked to cardiovascular inflammation
M Noval Rivas, D Wakita, MK Franklin, TT Carvalho, A Abolhesn, ...
Immunity 51 (3), 508-521. e6, 2019
1292019
TLR/MyD88 and liver X receptor α signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis
Y Naiki, R Sorrentino, MH Wong, KS Michelsen, K Shimada, S Chen, ...
The Journal of immunology 181 (10), 7176-7185, 2008
1252008
Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection
K Shimada, TR Crother, J Karlin, S Chen, N Chiba, VK Ramanujan, ...
PloS one 6 (6), e21477, 2011
1242011
Temporal Analysis of the Antigenic Composition of Borrelia burgdorferi during Infection in Rabbit Skin
TR Crother, CI Champion, JP Whitelegge, R Aguilera, XY Wu, DR Blanco, ...
Infection and immunity 72 (9), 5063-5072, 2004
1202004
Expansion of commensal fungus Wallemia mellicola in the gastrointestinal mycobiota enhances the severity of allergic airway disease in mice
JH Skalski, JJ Limon, P Sharma, MD Gargus, C Nguyen, J Tang, ...
PLoS pathogens 14 (9), e1007260, 2018
1102018
Role of interleukin-1 signaling in a mouse model of kawasaki disease–associated abdominal aortic aneurysm
D Wakita, Y Kurashima, TR Crother, M Noval Rivas, Y Lee, S Chen, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (5), 886-897, 2016
1092016
Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and-independent signaling and is reciprocally modulated by liver X receptor activation
S Chen, R Sorrentino, K Shimada, Y Bulut, TM Doherty, TR Crother, ...
The Journal of Immunology 181 (10), 7186-7193, 2008
1082008
IL-1 signaling is critically required in stromal cells in Kawasaki disease vasculitis mouse model: role of both IL-1α and IL-1β
Y Lee, D Wakita, J Dagvadorj, K Shimada, S Chen, G Huang, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (12), 2605-2616, 2015
1072015
Involvement of innate and adaptive immunity in a murine model of coronary arteritis mimicking Kawasaki disease
DJ Schulte, A Yilmaz, K Shimada, MC Fishbein, EL Lowe, S Chen, ...
The Journal of Immunology 183 (8), 5311-5318, 2009
982009
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