David Lodowski

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Krzysztof PalczewskiUCI ophthalmologyVerificeret mail på uci.edu
Mark ChanceCase Western Reserve UniversityVerificeret mail på case.edu
John TesmerPurdue UniversityVerificeret mail på purdue.edu
Dr. Marcin GolczakDepartment of Pharmacology, Case Western Reserve UniversityVerificeret mail på case.edu
Philip D. KiserUniversity of California Irvine and VA Long Beach Healthcare SystemVerificeret mail på uci.edu
Beata JastrzebskaCase Western Reserve UniversityVerificeret mail på case.edu
Robert J. LefkowitzJames B. Duke Professor of Medicine, Biochemistry, Chemistry; HHMI, Duke UniversityVerificeret mail på receptor-biol.duke.edu
Pitcher JAVerificeret mail på ucl.ac.uk
Z H ZhouUniversity of California, Los AngelesVerificeret mail på ucla.edu
Peter HegemannHertie Professor for Biophysics, Humboldt Universität zu BerlinVerificeret mail på rz.hu-berlin.de
Leonid S. BrownProfessor of Biophysics, University of GuelphVerificeret mail på uoguelph.ca
Taylor E. T. HughesPhD Candidate, University of PennsylvaniaVerificeret mail på pennmedicine.upenn.edu
Marta FilizolaDean and Professor at Icahn School of Medicine at Mount SinaiVerificeret mail på mssm.edu
Brian KobilkaStanford UniversityVerificeret mail på stanford.edu
Masaru Miyagi, Ph.D.Professor, Case Western Reserve UniversityVerificeret mail på case.edu
Jiansen JiangNational Institutes of HealthVerificeret mail på nih.gov
Ka Young ChungSungkyunkwan UniversityVerificeret mail på skku.edu
Yang DuThe Chinese University of Hong Kong, ShenzhenVerificeret mail på cuhk.edu.cn
Rohit JainSenior Research Associate, School of Medicine, Case Western Reserve University, Cleveland, OhioVerificeret mail på case.edu
Zhenghe WangDepartment of Genetics, Case Western Reserve UniversityVerificeret mail på case.edu

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David Lodowski

Assistant Professor Center for Proteomics and Bioinformatics, Case Western Reserve University

Verificeret mail på case.edu - Startside

Structural biology


Titel Sortér efter henvisninger Sortér efter årstal Sortér efter titel	Citeret af Citeret af	År
Microbial and animal rhodopsins: structures, functions, and molecular mechanisms OP Ernst, DT Lodowski, M Elstner, P Hegemann, LS Brown, H Kandori Chemical reviews 114 (1), 126-163, 2014	1225	2014
Crystal structure of a photoactivated deprotonated intermediate of rhodopsin D Salom, DT Lodowski, RE Stenkamp, IL Trong, M Golczak, ... Proceedings of the National Academy of Sciences 103 (44), 16123-16128, 2006	542	2006
Keeping G proteins at bay: A complex between G protein-coupled receptor kinase 2 and Gßγ DT Lodowski, JA Pitcher, WD Capel, RJ Lefkowitz, JJG Tesmer Science 300 (5623), 1256-1262, 2003	475	2003
The significance of G protein-coupled receptor crystallography for drug discovery JA Salon, DT Lodowski, K Palczewski Pharmacological reviews 63 (4), 901-937, 2011	272	2011
Structure of the full-length TRPV2 channel by cryo-EM KW Huynh, MR Cohen, J Jiang, A Samanta, DT Lodowski, ZH Zhou, ... Nature communications 7 (1), 11130, 2016	221	2016
Assembly of a GPCR-G protein complex Y Du, NM Duc, SGF Rasmussen, D Hilger, X Kubiak, L Wang, J Bohon, ... Cell 177 (5), 1232-1242. e11, 2019	210	2019
Activation of G protein–coupled receptors: beyond two-state models and tertiary conformational changes PSH Park, DT Lodowski, K Palczewski Annu. Rev. Pharmacol. Toxicol. 48 (1), 107-141, 2008	193	2008
Crystal structure of native RPE65, the retinoid isomerase of the visual cycle PD Kiser, M Golczak, DT Lodowski, MR Chance, K Palczewski Proceedings of the National Academy of Sciences 106 (41), 17325-17330, 2009	167	2009
Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1 N Mast, AJ Annalora, DT Lodowski, K Palczewski, CD Stout, IA Pikuleva Journal of Biological Chemistry 286 (7), 5607-5613, 2011	151	2011
Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM TET Hughes, DT Lodowski, KW Huynh, A Yazici, J Del Rosario, A Kapoor, ... Nature structural & molecular biology 25 (1), 53-60, 2018	125	2018
The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs DT Lodowski, VM Tesmer, JL Benovic, JJG Tesmer Journal of Biological Chemistry 281 (24), 16785-16793, 2006	125	2006
Structural basis for the acyltransferase activity of lecithin: retinol acyltransferase-like proteins M Golczak, PD Kiser, AE Sears, DT Lodowski, WS Blaner, K Palczewski Journal of biological chemistry 287 (28), 23790-23807, 2012	88	2012
Importance of membrane structural integrity for RPE65 retinoid isomerization activity M Golczak, PD Kiser, DT Lodowski, A Maeda, K Palczewski Journal of biological chemistry 285 (13), 9667-9682, 2010	80	2010
Chemokine receptors and other G protein-coupled receptors DT Lodowski, K Palczewski Current opinion in HIV and AIDS 4 (2), 88-95, 2009	79	2009
Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol JJG Tesmer, VM Tesmer, DT Lodowski, H Steinhagen, J Huber Journal of medicinal chemistry 53 (4), 1867-1870, 2010	75	2010
The role of Gβγ and domain interfaces in the activation of G protein-coupled receptor kinase 2 DT Lodowski, JF Barnhill, RM Pyskadlo, R Ghirlando, R Sterne-Marr, ... Biochemistry 44 (18), 6958-6970, 2005	67	2005
Comparative Analysis of GPCR Crystal Structures^† DT Lodowski, TE Angel, K Palczewski Photochemistry and photobiology 85 (2), 425-430, 2009	66	2009
Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals D Salom, I Le Trong, E Pohl, JA Ballesteros, RE Stenkamp, K Palczewski, ... Journal of structural biology 156 (3), 497-504, 2006	66	2006
Rhodopsin–transducin heteropentamer: Three-dimensional structure and biochemical characterization B Jastrzebska, P Ringler, DT Lodowski, V Moiseenkova-Bell, M Golczak, ... Journal of structural biology 176 (3), 387-394, 2011	63	2011
Novel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: biochemical and clinical evaluations W Sun, C Gerth, A Maeda, DT Lodowski, L Van Der Kraak, DA Saperstein, ... Vision research 47 (15), 2055-2066, 2007	63	2007

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