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Ioannis Zaganas
Ioannis Zaganas
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The glutamate dehydrogenase pathway and its roles in cell and tissue biology in health and disease
A Plaitakis, E Kalef-Ezra, D Kotzamani, I Zaganas, C Spanaki
Biology 6 (1), 11, 2017
2192017
Linking pesticide exposure and dementia: what is the evidence?
I Zaganas, S Kapetanaki, V Mastorodemos, K Kanavouras, C Colosio, ...
Toxicology 307, 3-11, 2013
2072013
Regulation of human glutamate dehydrogenases: implications for glutamate, ammonia and energy metabolism in brain
A Plaitakis, I Zaganas
Journal of Neuroscience Research 66 (5), 899-908, 2001
1402001
Eplontersen for hereditary transthyretin amyloidosis with polyneuropathy
T Coelho, W Marques, NR Dasgupta, CC Chao, Y Parman, MC França, ...
Jama 330 (15), 1448-1458, 2023
962023
Molecular basis of human glutamate dehydrogenase regulation under changing energy demands
V Mastorodemos, I Zaganas, C Spanaki, M Bessa, A Plaitakis
Journal of neuroscience research 79 (1‐2), 65-73, 2005
872005
Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cells
C Spanaki, I Zaganas, KA Kleopa, A Plaitakis
Journal of Biological Chemistry 285 (22), 16748-16756, 2010
812010
Study of structure–function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme
A Plaitakis, C Spanaki, V Mastorodemos, I Zaganas
Neurochemistry international 43 (4-5), 401-410, 2003
732003
Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum
V Mastorodemos, D Kotzamani, I Zaganas, G Arianoglou, H Latsoudis, ...
Biochemistry and cell biology 87 (3), 505-516, 2009
662009
Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex
I Zaganas, HS Waagepetersen, P Georgopoulos, U Sonnewald, ...
Journal of neuroscience research 66 (5), 909-913, 2001
632001
Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset
A Plaitakis, H Latsoudis, K Kanavouras, B Ritz, JM Bronstein, I Skoula, ...
European journal of human genetics 18 (3), 336-341, 2010
622010
Cerebrospinal fluid TAR DNA-binding protein 43 combined with tau proteins as a candidate biomarker for amyotrophic lateral sclerosis and frontotemporal dementia spectrum disorders
M Bourbouli, M Rentzos, A Bougea, V Zouvelou, VC Constantinides, ...
Dementia and Geriatric Cognitive Disorders 44 (3-4), 144-152, 2017
602017
Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes …
I Zaganas, A Plaitakis
Journal of Biological Chemistry 277 (29), 26422-26428, 2002
572002
Associations between sleep duration and cognitive impairment in mild cognitive impairment
M Basta, P Simos, A Vgontzas, E Koutentaki, S Tziraki, I Zaganas, ...
Journal of Sleep Research 28 (6), e12864, 2019
552019
Age-related decline in verbal learning is moderated by demographic factors, working memory capacity, and presence of amnestic mild cognitive impairment
F Constantinidou, I Zaganas, E Papastefanakis, D Kasselimis, A Nidos, ...
Journal of the International Neuropsychological Society 20 (8), 822-835, 2014
552014
Myelin content changes in probable Alzheimer's disease and mild cognitive impairment: associations with age and severity of neuropsychiatric impairment
E Kavroulakis, PG Simos, G Kalaitzakis, TG Maris, D Karageorgou, ...
Journal of Magnetic Resonance Imaging 47 (5), 1359-1372, 2018
522018
Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the …
I Zaganas, C Spanaki, M Karpusas, A Plaitakis
Journal of Biological Chemistry 277 (48), 46552-46558, 2002
502002
Expression of human GLUD2 glutamate dehydrogenase in human tissues: functional implications
I Zaganas, C Spanaki, A Plaitakis
Neurochemistry international 61 (4), 455-462, 2012
432012
Peptide EphB2/CTF2 generated by the γ-secretase processing of EphB2 receptor promotes tyrosine phosphorylation and cell surface localization of N-Methyl-d-aspartate receptors
J Xu, C Litterst, A Georgakopoulos, I Zaganas, NK Robakis
Journal of Biological Chemistry 284 (40), 27220-27228, 2009
412009
Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes
JD Nissen, K Lykke, J Bryk, MH Stridh, I Zaganas, DM Skytt, A Schousboe, ...
Glia 65 (3), 474-488, 2017
392017
Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways
SM Hutson, MM Islam, I Zaganas
Neurochemistry international 59 (4), 518-524, 2011
392011
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