| “Inside-out” signaling of sphingosine-1-phosphate: therapeutic targets K Takabe, SW Paugh, S Milstien, S Spiegel Pharmacological reviews 60 (2), 181-195, 2008 | 869 | 2008 |
| Genomic and transcriptomic landscape of triple-negative breast cancers: subtypes and treatment strategies YZ Jiang, D Ma, C Suo, J Shi, M Xue, X Hu, Y Xiao, KD Yu, YR Liu, Y Yu, ... Cancer cell 35 (3), 428-440. e5, 2019 | 831 | 2019 |
| Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer J Liang, M Nagahashi, EY Kim, KB Harikumar, A Yamada, WC Huang, ... Cancer cell 23 (1), 107-120, 2013 | 617 | 2013 |
| Cancer cachexia, mechanism and treatment T Aoyagi, KP Terracina, A Raza, H Matsubara, K Takabe World journal of gastrointestinal oncology 7 (4), 17, 2015 | 536 | 2015 |
| Targeting SphK1 as a new strategy against cancer D Shida, K Takabe, D Kapitonov, S Milstien, S Spiegel Current drug targets 9 (8), 662-673, 2008 | 399 | 2008 |
| Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis M Nagahashi, S Ramachandran, EY Kim, JC Allegood, OM Rashid, ... Cancer research 72 (3), 726-735, 2012 | 362 | 2012 |
| Conjugated bile acids activate the sphingosine‐1‐phosphate receptor 2 in primary rodent hepatocytes E Studer, X Zhou, R Zhao, Y Wang, K Takabe, M Nagahashi, WM Pandak, ... Hepatology 55 (1), 267-276, 2012 | 326 | 2012 |
| Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2 K Takabe, RH Kim, JC Allegood, P Mitra, S Ramachandran, M Nagahashi, ... Journal of Biological Chemistry 285 (14), 10477-10486, 2010 | 319 | 2010 |
| Sustained correction of bleeding disorder in hemophilia B mice by gene therapy L Wang, K Takabe, SM Bidlingmaier, IM Verma Proceedings of the National Academy of Sciences 96 (7), 3906-3910, 1999 | 294 | 1999 |
| Sphingosine‐1‐phosphate signaling in immune cells and inflammation: roles and therapeutic potential M Aoki, H Aoki, R Ramanathan, NC Hait, K Takabe Mediators of inflammation 2016 (1), 8606878, 2016 | 259 | 2016 |
| Export and functions of sphingosine-1-phosphate RH Kim, K Takabe, S Milstien, S Spiegel Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2009 | 242 | 2009 |
| The role of sphingosine 1‐phosphate receptor 2 in bile‐acid–induced cholangiocyte proliferation and cholestasis‐induced liver injury in mice Y Wang, H Aoki, J Yang, K Peng, R Liu, X Li, X Qiang, L Sun, EC Gurley, ... Hepatology 65 (6), 2005-2018, 2017 | 205 | 2017 |
| Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression M Nagahashi, K Takabe, R Liu, K Peng, X Wang, Y Wang, NC Hait, ... Hepatology 61 (4), 1216-1226, 2015 | 198 | 2015 |
| Targeting the SphK1/S1P/S1PR1 axis that links obesity, chronic inflammation, and breast cancer metastasis M Nagahashi, A Yamada, E Katsuta, T Aoyagi, WC Huang, KP Terracina, ... Cancer research 78 (7), 1713-1725, 2018 | 197 | 2018 |
| High expression of ATP-binding cassette transporter ABCC11 in breast tumors is associated with aggressive subtypes and low disease-free survival A Yamada, T Ishikawa, I Ota, M Kimura, D Shimizu, M Tanabe, ... Breast cancer research and treatment 137, 773-782, 2013 | 195 | 2013 |
| CD8 T cell score as a prognostic biomarker for triple negative breast cancer M Oshi, M Asaoka, Y Tokumaru, L Yan, R Matsuyama, T Ishikawa, I Endo, ... International journal of molecular sciences 21 (18), 6968, 2020 | 190 | 2020 |
| Export of sphingosine-1-phosphate and cancer progression K Takabe, S Spiegel Journal of lipid research 55 (9), 1839-1846, 2014 | 189 | 2014 |
| M1 Macrophage and M1/M2 ratio defined by transcriptomic signatures resemble only part of their conventional clinical characteristics in breast cancer M Oshi, Y Tokumaru, M Asaoka, L Yan, V Satyananda, R Matsuyama, ... Scientific reports 10 (1), 16554, 2020 | 176 | 2020 |
| Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network M Nagahashi, EY Kim, A Yamada, S Ramachandran, JC Allegood, ... The FASEB Journal 27 (3), 1001, 2013 | 176 | 2013 |
| Cross-talk between LPA1 and Epidermal Growth Factor Receptors Mediates Up-regulation of Sphingosine Kinase 1 to Promote Gastric Cancer Cell Motility and … D Shida, X Fang, T Kordula, K Takabe, S Lepine, SE Alvarez, S Milstien, ... Cancer research 68 (16), 6569-6577, 2008 | 174 | 2008 |
Masayuki NagahashiHyogo College of MedicineVerificeret mail på hyo-med.ac.jp