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Joshua Munger
Joshua Munger
Verificeret mail på urmc.rochester.edu
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The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
R Wang, CP Dillon, LZ Shi, S Milasta, R Carter, D Finkelstein, ...
Immunity 35 (6), 871-882, 2011
22622011
Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy
J Munger, BD Bennett, A Parikh, XJ Feng, J McArdle, HA Rabitz, T Shenk, ...
Nature biotechnology 26 (10), 1179-1186, 2008
7212008
A roadmap for interpreting 13C metabolite labeling patterns from cells
JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ...
Current opinion in biotechnology 34, 189-201, 2015
6722015
IDH1 (R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
M Sasaki, CB Knobbe, JC Munger, EF Lind, D Brenner, A Brüstle, ...
Nature 488 (7413), 656-659, 2012
6322012
Dynamics of the cellular metabolome during human cytomegalovirus infection
J Munger, SU Bajad, HA Coller, T Shenk, JD Rabinowitz
PLoS pathogens 2 (12), e132, 2006
4932006
Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells
S Pei, M Minhajuddin, KP Callahan, M Balys, JM Ashton, SJ Neering, ...
Journal of Biological Chemistry 288 (47), 33542-33558, 2013
2312013
Stealing the keys to the kitchen: viral manipulation of the host cell metabolic network
CM Goodwin, S Xu, J Munger
Trends in microbiology 23 (12), 789-798, 2015
2132015
The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the …
J Munger, B Roizman
Proceedings of the National Academy of Sciences 98 (18), 10410-10415, 2001
1942001
Accumulation of succinate in cardiac ischemia primarily occurs via canonical krebs cycle activity
J Zhang, YT Wang, JH Miller, MM Day, JC Munger, PS Brookes
Cell reports 23 (9), 2617-2628, 2018
1852018
Addiction to coupling of the Warburg effect with glutamine catabolism in cancer cells
B Smith, XL Schafer, A Ambeskovic, CM Spencer, H Land, J Munger
Cell reports 17 (3), 821-836, 2016
1622016
Metabolite profiles of human immunodeficiency virus infected CD4+ T cells and macrophages using LC–MS/MS analysis
JA Hollenbaugh, J Munger, B Kim
Virology 415 (2), 153-159, 2011
1582011
Acidic pH is a metabolic switch for 2-hydroxyglutarate generation and signaling
SM Nadtochiy, X Schafer, D Fu, K Nehrke, J Munger, PS Brookes
Journal of Biological Chemistry 291 (38), 20188-20197, 2016
1512016
The US3 Protein Kinase Blocks Apoptosis Induced by the d120 Mutant of Herpes Simplex Virus 1 at a Premitochondrial Stage
J Munger, AV Chee, B Roizman
Journal of virology 75 (12), 5491-5497, 2001
1372001
HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication
J McArdle, NJ Moorman, J Munger
PLoS pathogens 8 (1), e1002502, 2012
1342012
Human cytomegalovirus induces the activity and expression of acetyl-coenzyme A carboxylase, a fatty acid biosynthetic enzyme whose inhibition attenuates viral replication
CM Spencer, XL Schafer, NJ Moorman, J Munger
Journal of virology 85 (12), 5814-5824, 2011
1302011
Inhibition of calmodulin-dependent kinase kinase blocks human cytomegalovirus-induced glycolytic activation and severely attenuates production of viral progeny
J McArdle, XL Schafer, J Munger
Journal of virology 85 (2), 705-714, 2011
1072011
The Herpes Simplex Virus 1 US3 Protein Kinase Blocks Caspase-Dependent Double Cleavage and Activation of the Proapoptotic Protein BAD
L Benetti, J Munger, B Roizman
Journal of virology 77 (11), 6567-6573, 2003
1022003
US3 Protein Kinase of Herpes Simplex Virus 1 Blocks Caspase 3 Activation Induced by the Products of US1.5 and UL13 Genes and Modulates Expression of Transduced U …
R Hagglund, J Munger, APW Poon, B Roizman
Journal of Virology 76 (2), 743-754, 2002
832002
Cytomegalovirus-mediated activation of pyrimidine biosynthesis drives UDP–sugar synthesis to support viral protein glycosylation
SR DeVito, E Ortiz-Riaño, L Martínez-Sobrido, J Munger
Proceedings of the National Academy of Sciences 111 (50), 18019-18024, 2014
772014
UL26-deficient human cytomegalovirus produces virions with hypophosphorylated pp28 tegument protein that is unstable within newly infected cells
J Munger, D Yu, T Shenk
Journal of virology 80 (7), 3541-3548, 2006
752006
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Artikler 1–20