The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation R Wang, CP Dillon, LZ Shi, S Milasta, R Carter, D Finkelstein, ... Immunity 35 (6), 871-882, 2011 | 2262 | 2011 |
Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy J Munger, BD Bennett, A Parikh, XJ Feng, J McArdle, HA Rabitz, T Shenk, ... Nature biotechnology 26 (10), 1179-1186, 2008 | 721 | 2008 |
A roadmap for interpreting 13C metabolite labeling patterns from cells JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ... Current opinion in biotechnology 34, 189-201, 2015 | 672 | 2015 |
IDH1 (R132H) mutation increases murine haematopoietic progenitors and alters epigenetics M Sasaki, CB Knobbe, JC Munger, EF Lind, D Brenner, A Brüstle, ... Nature 488 (7413), 656-659, 2012 | 632 | 2012 |
Dynamics of the cellular metabolome during human cytomegalovirus infection J Munger, SU Bajad, HA Coller, T Shenk, JD Rabinowitz PLoS pathogens 2 (12), e132, 2006 | 493 | 2006 |
Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells S Pei, M Minhajuddin, KP Callahan, M Balys, JM Ashton, SJ Neering, ... Journal of Biological Chemistry 288 (47), 33542-33558, 2013 | 231 | 2013 |
Stealing the keys to the kitchen: viral manipulation of the host cell metabolic network CM Goodwin, S Xu, J Munger Trends in microbiology 23 (12), 789-798, 2015 | 213 | 2015 |
The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the … J Munger, B Roizman Proceedings of the National Academy of Sciences 98 (18), 10410-10415, 2001 | 194 | 2001 |
Accumulation of succinate in cardiac ischemia primarily occurs via canonical krebs cycle activity J Zhang, YT Wang, JH Miller, MM Day, JC Munger, PS Brookes Cell reports 23 (9), 2617-2628, 2018 | 185 | 2018 |
Addiction to coupling of the Warburg effect with glutamine catabolism in cancer cells B Smith, XL Schafer, A Ambeskovic, CM Spencer, H Land, J Munger Cell reports 17 (3), 821-836, 2016 | 162 | 2016 |
Metabolite profiles of human immunodeficiency virus infected CD4+ T cells and macrophages using LC–MS/MS analysis JA Hollenbaugh, J Munger, B Kim Virology 415 (2), 153-159, 2011 | 158 | 2011 |
Acidic pH is a metabolic switch for 2-hydroxyglutarate generation and signaling SM Nadtochiy, X Schafer, D Fu, K Nehrke, J Munger, PS Brookes Journal of Biological Chemistry 291 (38), 20188-20197, 2016 | 151 | 2016 |
The US3 Protein Kinase Blocks Apoptosis Induced by the d120 Mutant of Herpes Simplex Virus 1 at a Premitochondrial Stage J Munger, AV Chee, B Roizman Journal of virology 75 (12), 5491-5497, 2001 | 137 | 2001 |
HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication J McArdle, NJ Moorman, J Munger PLoS pathogens 8 (1), e1002502, 2012 | 134 | 2012 |
Human cytomegalovirus induces the activity and expression of acetyl-coenzyme A carboxylase, a fatty acid biosynthetic enzyme whose inhibition attenuates viral replication CM Spencer, XL Schafer, NJ Moorman, J Munger Journal of virology 85 (12), 5814-5824, 2011 | 130 | 2011 |
Inhibition of calmodulin-dependent kinase kinase blocks human cytomegalovirus-induced glycolytic activation and severely attenuates production of viral progeny J McArdle, XL Schafer, J Munger Journal of virology 85 (2), 705-714, 2011 | 107 | 2011 |
The Herpes Simplex Virus 1 US3 Protein Kinase Blocks Caspase-Dependent Double Cleavage and Activation of the Proapoptotic Protein BAD L Benetti, J Munger, B Roizman Journal of virology 77 (11), 6567-6573, 2003 | 102 | 2003 |
US3 Protein Kinase of Herpes Simplex Virus 1 Blocks Caspase 3 Activation Induced by the Products of US1.5 and UL13 Genes and Modulates Expression of Transduced U … R Hagglund, J Munger, APW Poon, B Roizman Journal of Virology 76 (2), 743-754, 2002 | 83 | 2002 |
Cytomegalovirus-mediated activation of pyrimidine biosynthesis drives UDP–sugar synthesis to support viral protein glycosylation SR DeVito, E Ortiz-Riaño, L Martínez-Sobrido, J Munger Proceedings of the National Academy of Sciences 111 (50), 18019-18024, 2014 | 77 | 2014 |
UL26-deficient human cytomegalovirus produces virions with hypophosphorylated pp28 tegument protein that is unstable within newly infected cells J Munger, D Yu, T Shenk Journal of virology 80 (7), 3541-3548, 2006 | 75 | 2006 |