| Functional profiling of the Saccharomyces cerevisiae genome G Giaever, AM Chu, L Ni, C Connelly, L Riles, S Veronneau, S Dow, ... nature 418 (6896), 387-391, 2002 | 5224 | 2002 |
| Itraconazole resistance in Aspergillus fumigatus. DW Denning, K Venkateswarlu, KL Oakley, MJ Anderson, NJ Manning, ... Antimicrobial agents and chemotherapy 41 (6), 1364-1368, 1997 | 622 | 1997 |
| Molecular basis of resistance to azole antifungals A Lupetti, R Danesi, M Campa, M Del Tacca, S Kelly Trends in molecular medicine 8 (2), 76-81, 2002 | 601 | 2002 |
| Resistance to fluconazole and cross‐resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol Δ5, 6‐desaturation SL Kelly, DC Lamb, DE Kelly, NJ Manning, J Loeffler, H Hebart, ... FEBS letters 400 (1), 80-82, 1997 | 470 | 1997 |
| Multiple molecular mechanisms contribute to a stepwise development of fluconazole resistance in clinical Candida albicans strains R Franz, SL Kelly, DC Lamb, DE Kelly, M Ruhnke, J Morschhäuser Antimicrobial agents and chemotherapy 42 (12), 3065-3072, 1998 | 435 | 1998 |
| Mode of action and resistance to azole antifungals associated with the formation of 14α-methylergosta-8, 24 (28)-dien-3β, 6α-diol SL Kelly, DC Lamb, AJ Corran, BC Baldwin, DE Kelly Biochemical and biophysical research communications 207 (3), 910-915, 1995 | 342 | 1995 |
| Azole fungicides–understanding resistance mechanisms in agricultural fungal pathogens CL Price, JE Parker, AGS Warrilow, DE Kelly, SL Kelly Pest management science 71 (8), 1054-1058, 2015 | 308 | 2015 |
| The mutation T315A in Candida albicans sterol 14α-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity DC Lamb, DE Kelly, WH Schunck, AZ Shyadehi, M Akhtar, DJ Lowe, ... Journal of Biological Chemistry 272 (9), 5682-5688, 1997 | 258 | 1997 |
| Microbial cytochromes P450: biodiversity and biotechnology. Where do cytochromes P450 come from, what do they do and what can they do for us? SL Kelly, DE Kelly Phil. Trans. R. Soc. B 368 (1612), 20120476, 2013 | 256 | 2013 |
| Defective sterol C5-6 desaturation and azole resistance: a new hypothesis for the mode of action of azole antifungals PF Watson, ME Rose, SW Ellis, H England, SL Kelly Biochemical and biophysical research communications 164 (3), 1170-1175, 1989 | 239 | 1989 |
| The first virally encoded cytochrome p450 DC Lamb, L Lei, AGS Warrilow, GI Lepesheva, JGL Mullins, ... Journal of virology 83 (16), 8266-8269, 2009 | 233 | 2009 |
| Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3 (2) B Zhao, X Lin, L Lei, DC Lamb, SL Kelly, MR Waterman, DE Cane Journal of Biological Chemistry 283 (13), 8183-8189, 2008 | 216 | 2008 |
| Identification and characterization of four azole-resistant erg3 mutants of Candida albicans CM Martel, JE Parker, O Bader, M Weig, U Gross, AGS Warrilow, N Rolley, ... Antimicrobial agents and chemotherapy 54 (11), 4527-4533, 2010 | 214 | 2010 |
| Resistance to antifungals that target CYP51 JE Parker, AGS Warrilow, CL Price, JGL Mullins, DE Kelly, SL Kelly Journal of Chemical Biology, 1-19, 2014 | 206 | 2014 |
| Molecular analysis of cyp51 from fluconazole‐resistant Candida albicans strains J Löffler, SL Kelly, H Hebart, U Schumacher, C Lass‐Flörl, H Einsele FEMS microbiology letters 151 (2), 263-268, 1997 | 205 | 1997 |
| A clinical isolate of Candida albicans with mutations in ERG11 (encoding sterol 14α-demethylase) and ERG5 (encoding C22 desaturase) is cross resistant to azoles and amphotericin B CM Martel, JE Parker, O Bader, M Weig, U Gross, AGS Warrilow, DE Kelly, ... Antimicrobial agents and chemotherapy 54 (9), 3578-3583, 2010 | 195 | 2010 |
| Systematic analysis of yeast strains with possible defects in lipid metabolism G Daum, G Tuller, T Nemec, C Hrastnik, G Balliano, L Cattel, P Milla, ... Yeast 15 (7), 601-614, 1999 | 194 | 1999 |
| Characterization of the sterol 14α‐demethylases of Fusarium graminearum identifies a novel genus‐specific CYP51 function J Fan, M Urban, JE Parker, HC Brewer, SL Kelly, KE Hammond‐Kosack, ... New Phytologist 198 (3), 821-835, 2013 | 187 | 2013 |
| Binding of two flaviolin substrate molecules, oxidative coupling, and crystal structure of Streptomyces coelicolor A3 (2) cytochrome P450 158A2 B Zhao, FP Guengerich, A Bellamine, DC Lamb, M Izumikawa, L Lei, ... Journal of Biological Chemistry 280 (12), 11599-11607, 2005 | 181 | 2005 |
| The R467K amino acid substitution in Candida albicans sterol 14α-demethylase causes drug resistance through reduced affinity DC Lamb, DE Kelly, TC White, SL Kelly Antimicrobial agents and chemotherapy 44 (1), 63-67, 2000 | 173 | 2000 |
David C LambSwansea UniversityVerificeret mail på swansea.ac.uk