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Slayden, richard
Slayden, richard
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Mycolic acids: structure, biosynthesis and physiological functions
CE Barry Iii, RE Lee, K Mdluli, AE Sampson, BG Schroeder, RA Slayden, ...
Progress in lipid research 37 (2-3), 143-179, 1998
7861998
Inhibition of a Mycobacterium tuberculosis β-Ketoacyl ACP Synthase by Isoniazid
K Mdluli, RA Slayden, YQ Zhu, S Ramaswamy, X Pan, D Mead, DD Crane, ...
Science 280 (5369), 1607-1610, 1998
6111998
Biogenesis of the mycobacterial cell wall and the site of action of ethambutol
K Mikusova, RA Slayden, GS Besra, PJ Brennan
Antimicrobial agents and chemotherapy 39 (11), 2484-2489, 1995
4421995
The genetics and biochemistry of isoniazid resistance in Mycobacterium tuberculosis
RA Slayden, CE Barry III
Microbes and Infection 2 (6), 659-669, 2000
3262000
High affinity InhA inhibitors with activity against drug-resistant strains of Mycobacterium tuberculosis
TJ Sullivan, JJ Truglio, ME Boyne, P Novichenok, X Zhang, CF Stratton, ...
ACS chemical biology 1 (1), 43-53, 2006
3162006
Combinatorial lead optimization of [1, 2]-diamines based on ethambutol as potential antituberculosis preclinical candidates
RE Lee, M Protopopova, E Crooks, RA Slayden, M Terrot, CE Barry
Journal of combinatorial chemistry 5 (2), 172-187, 2003
3012003
Hypoxic Response of Mycobacterium tuberculosis Studied by Metabolic Labeling and Proteome Analysis of Cellular and Extracellular Proteins
I Rosenkrands, RA Slayden, J Crawford, C Aagaard, CE Barry III, ...
Journal of bacteriology 184 (13), 3485-3491, 2002
2592002
Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis
B Phetsuksiri, M Jackson, H Scherman, M McNeil, GS Besra, AR Baulard, ...
Journal of Biological Chemistry 278 (52), 53123-53130, 2003
2152003
Isoniazid affects multiple components of the type II fatty acid synthase system of Mycobacterium tuberculosis
RA Slayden, RE Lee, CE Barry 3rd
Molecular microbiology 38 (3), 514-525, 2000
2152000
Use of genomics and combinatorial chemistry in the development of new antimycobacterial drugs
CE Barry III, RA Slayden, AE Sampson, RE Lee
Biochemical pharmacology 59 (3), 221-231, 2000
2032000
Novel Trisubstituted Benzimidazoles, Targeting Mtb FtsZ, as a New Class of Antitubercular Agents
K Kumar, D Awasthi, SY Lee, I Zanardi, B Ruzsicska, S Knudson, ...
Journal of medicinal chemistry 54 (1), 374-381, 2011
2022011
Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis
RA Slayden, RE Lee, JW Armour, AM Cooper, IM Orme, PJ Brennan, ...
Antimicrobial agents and chemotherapy 40 (12), 2813-2819, 1996
2011996
Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non‐replicating persistence
RK Dhiman, S Mahapatra, RA Slayden, ME Boyne, A Lenaerts, ...
Molecular microbiology 72 (1), 85-97, 2009
1732009
Disease state differentiation and identification of tuberculosis biomarkers via native antigen array profiling
MJ Sartain, RA Slayden, KK Singh, S Laal, JT Belisle
Molecular & cellular proteomics 5 (11), 2102-2113, 2006
1462006
Targeting FtsZ for antituberculosis drug discovery: noncytotoxic taxanes as novel antituberculosis agents
Q Huang, F Kirikae, T Kirikae, A Pepe, A Amin, L Respicio, RA Slayden, ...
Journal of medicinal chemistry 49 (2), 463-466, 2006
1412006
Slow-Onset Inhibition of the FabI Enoyl Reductase from Francisella tularensis: Residence Time and in Vivo Activity
H Lu, K England, C am Ende, JJ Truglio, S Luckner, BG Reddy, ...
ACS chemical biology 4 (3), 221-231, 2009
1392009
Synthesis and SAR studies of 1, 4-benzoxazine MenB inhibitors: Novel antibacterial agents against Mycobacterium tuberculosis
X Li, N Liu, H Zhang, SE Knudson, RA Slayden, PJ Tonge
Bioorganic & medicinal chemistry letters 20 (21), 6306-6309, 2010
1302010
Identification of cell cycle regulators in Mycobacterium tuberculosis by inhibition of septum formation and global transcriptional analysis
RA Slayden, DL Knudson, JT Belisle
Microbiology 152 (6), 1789-1797, 2006
1302006
Identification of the apparent carrier in mycolic acid synthesis.
GS Besra, T Sievert, RE Lee, RA Slayden, PJ Brennan, K Takayama
Proceedings of the National Academy of Sciences 91 (26), 12735-12739, 1994
1201994
A Point Mutation in the mma3 Gene Is Responsible for Impaired Methoxymycolic Acid Production in Mycobacterium bovis BCG Strains Obtained after 1927
MA Behr, BG Schroeder, JN Brinkman, RA Slayden, CE Barry III
Journal of bacteriology 182 (12), 3394-3399, 2000
1192000
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