Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia L Braga, H Ali, I Secco, E Chiavacci, G Neves, D Goldhill, R Penn, ... Nature 594 (7861), 88-93, 2021 | 399 | 2021 |
3D microfluidic liver cultures as a physiological preclinical tool for hepatitis B virus infection AM Ortega-Prieto, JK Skelton, SN Wai, E Large, M Lussignol, ... Nature communications 9 (1), 682, 2018 | 228 | 2018 |
Human organs-on-chips for virology H Tang, Y Abouleila, L Si, AM Ortega-Prieto, CL Mummery, DE Ingber, ... Trends in microbiology 28 (11), 934-946, 2020 | 117 | 2020 |
Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern L Dupont, LB Snell, C Graham, J Seow, B Merrick, T Lechmere, ... Nature microbiology 6 (11), 1433-1442, 2021 | 105 | 2021 |
Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis AM Ortega-Prieto, J Sheldon, A Grande-Pérez, H Tejero, J Gregori, J Quer, ... PloS one 8 (8), e71039, 2013 | 84 | 2013 |
Immune evasion strategies during chronic hepatitis B and C virus infection AM Ortega-Prieto, M Dorner Vaccines 5 (3), 24, 2017 | 72 | 2017 |
A Hitchhiker's guide to humanized mice: new pathways to studying viral infections JK Skelton, AM Ortega‐Prieto, M Dorner Immunology 154 (1), 50-61, 2018 | 67 | 2018 |
T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses CJ Reynolds, OM Suleyman, AM Ortega-Prieto, JK Skelton, ... Scientific reports 8 (1), 672, 2018 | 65 | 2018 |
Identification of broad-spectrum antiviral compounds by targeting viral entry M Mazzon, AM Ortega-Prieto, D Imrie, C Luft, L Hess, S Czieso, J Grove, ... Viruses 11 (2), 176, 2019 | 60 | 2019 |
An overview of vaccines against SARS-CoV-2 in the COVID-19 pandemic era A Pascual-Iglesias, J Canton, AM Ortega-Prieto, JM Jimenez-Guardeño, ... Pathogens 10 (8), 1030, 2021 | 51 | 2021 |
Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS LJ Pallett, L Swadling, M Diniz, AA Maini, M Schwabenland, AD Gasull, ... Nature 614 (7947), 334-342, 2023 | 47 | 2023 |
Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation MJ Lista, PM Matos, TJA Maguire, K Poulton, E Ortiz-Zapater, R Page, ... PLoS One 16 (9), e0256813, 2021 | 38 | 2021 |
In Vivo Model Systems for Hepatitis B Virus Research AM Ortega-Prieto, C Cherry, H Gunn, M Dorner ACS Infectious Diseases 5 (5), 688-702, 2018 | 36 | 2018 |
Human Monkeypox: a comprehensive overview of epidemiology, pathogenesis, diagnosis, treatment, and prevention strategies DE Martínez-Fernández, D Fernández-Quezada, FAG Casillas-Muñoz, ... Pathogens 12 (7), 947, 2023 | 31* | 2023 |
" Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection AM Ortega-Prieto, JK Skelton, C Cherry, MA Briones-Orta, CA Hateley, ... Journal of Visualized Experiments (JoVE), e58333, 2019 | 28 | 2019 |
Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models PJ Liu, JM Harris, E Marchi, V D’arienzo, T Michler, PAC Wing, A Magri, ... Scientific Reports 10 (1), 14101, 2020 | 18 | 2020 |
Phosphodiesterase-induced cAMP degradation restricts hepatitis B virus infection AA Evripioti, AM Ortega-Prieto, JK Skelton, Q Bazot, M Dorner Philosophical Transactions of the Royal Society B 374 (1773), 20180292, 2019 | 14 | 2019 |
Drug repurposing based on a quantum-inspired method versus classical fingerprinting uncovers potential antivirals against SARS-CoV-2 JM Jimenez-Guardeño, AM Ortega-Prieto, B Menendez Moreno, ... PLoS computational biology 18 (7), e1010330, 2022 | 13 | 2022 |
Development of a structural epitope mimic: An idiotypic approach to HCV vaccine design VM Cowton, AM Owsianka, V Fadda, AM Ortega-Prieto, SJ Cole, JA Potter, ... npj Vaccines 6 (1), 1-10, 2021 | 13 | 2021 |
3D microfluidic liver cultures as a physiological preclinical tool for hepatitis B virus infection. Nat Commun 9: 682 AM Ortega-Prieto, JK Skelton, SN Wai, E Large, M Lussignol, ... | 12 | 2018 |