Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity P Akbari, A Gilani, O Sosina, JA Kosmicki, L Khrimian, YY Fang, ... Science 373 (6550), 2021 | 229 | 2021 |
Endothelial NOS: perspective and recent developments V Garcia, WC Sessa British journal of pharmacology 176 (2), 189-196, 2019 | 176 | 2019 |
20-HETE Signals Through G-Protein–Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension V Garcia, A Gilani, B Shkolnik, V Pandey, FF Zhang, R Dakarapu, ... Circulation research 120 (11), 1776-1788, 2017 | 169 | 2017 |
20-HETE and blood pressure regulation: clinical implications CC Wu, T Gupta, V Garcia, Y Ding, ML Schwartzman Cardiology in review 22 (1), 1, 2014 | 169 | 2014 |
Vascular actions of 20-HETE SL Hoopes, V Garcia, ML Edin, ML Schwartzman, DC Zeldin Prostaglandins & other lipid mediators 120, 9-16, 2015 | 150 | 2015 |
Induction of Angiotensin-Converting Enzyme and Activation of the Renin–Angiotensin System Contribute to 20-Hydroxyeicosatetraenoic Acid–Mediated Endothelial Dysfunction J Cheng, V Garcia, Y Ding, CC Wu, K Thakar, JR Falck, E Ramu, ... Arteriosclerosis, thrombosis, and vascular biology 32 (8), 1917-1924, 2012 | 78 | 2012 |
Androgen-sensitive hypertension associates with upregulated vascular CYP4A12–20-HETE synthase CC Wu, S Mei, J Cheng, Y Ding, A Weidenhammer, V Garcia, F Zhang, ... Journal of the American Society of Nephrology 24 (8), 1288-1296, 2013 | 66 | 2013 |
20-HETE activates the transcription of angiotensin-converting enzyme via nuclear factor-κB translocation and promoter binding V Garcia, B Shkolnik, L Milhau, JR Falck, ML Schwartzman Journal of Pharmacology and Experimental Therapeutics 356 (3), 525-533, 2016 | 63 | 2016 |
Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid–mediated kidney injury in diabetic nephropathy MH Gangadhariah, JM Luther, V Garcia, P Paueksakon, MZ Zhang, ... Journal of the American Society of Nephrology 26 (3), 597-610, 2015 | 54 | 2015 |
High-fat diet-induced obesity and insulin resistance in CYP4a14−/− mice is mediated by 20-HETE A Gilani, V Pandey, V Garcia, K Agostinucci, SP Singh, J Schragenheim, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2018 | 50 | 2018 |
Vascular characterization of mice with endothelial expression of cytochrome P450 4F2 J Cheng, ML Edin, SL Hoopes, H Li, JA Bradbury, JP Graves, LM DeGraff, ... The FASEB Journal 28 (7), 2915-2931, 2014 | 50 | 2014 |
20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension Y Ding, CC Wu, V Garcia, I Dimitrova, A Weidenhammer, G Joseph, ... American Journal of Physiology-Renal Physiology 305 (5), F753-F763, 2013 | 49 | 2013 |
Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension V Garcia, G Joseph, B Shkolnik, Y Ding, FF Zhang, K Gotlinger, JR Falck, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2015 | 47 | 2015 |
Uncovering the signaling, structure and function of the 20‐HETE‐GPR75 pairing: Identifying CCL5 as a negative regulator of GPR75 JV Pascale, EJ Park, AM Adebesin, JR Falck, ML Schwartzman, V Garcia British Journal of Pharmacology, 2021 | 34 | 2021 |
20-HETE interferes with insulin signaling and contributes to obesity-driven insulin resistance A Gilani, K Agostinucci, S Hossain, JV Pascale, V Garcia, AM Adebesin, ... Prostaglandins & Other Lipid Mediators 152, 106485, 2021 | 34 | 2021 |
Heme-oxygenase and lipid mediators in obesity and associated cardiometabolic diseases: Therapeutic implications JA McClung, L Levy, V Garcia, DE Stec, SJ Peterson, NG Abraham Pharmacology & Therapeutics, 107975, 2021 | 33 | 2021 |
Androgen-induced hypertension in angiotensinogen deficient mice: role of 20-HETE and EETS V Garcia, J Cheng, A Weidenhammer, Y Ding, CC Wu, F Zhang, ... Prostaglandins & other lipid mediators 116, 124-130, 2015 | 30 | 2015 |
Unbiased proteomics identifies plasminogen activator inhibitor-1 as a negative regulator of endothelial nitric oxide synthase V Garcia, EJ Park, M Siragusa, F Frohlich, MM Haque, JV Pascale, ... Proceedings of the National Academy of Sciences 117 (17), 9497-9507, 2020 | 29 | 2020 |
Recent developments on the vascular effects of 20-hydroxyeicosatetraenoic acid V Garcia, ML Schwartzman Current opinion in nephrology and hypertension 26 (2), 74-82, 2017 | 28 | 2017 |
CYP4A/20-HETE regulates ischemia-induced neovascularization via its actions on endothelial progenitor and preexisting endothelial cells L Chen, S Tang, FF Zhang, V Garcia, JR Falck, ML Schwartzman, ... American Journal of Physiology-Heart and Circulatory Physiology 316 (6 …, 2019 | 25 | 2019 |