Bowman-Birk Inhibitors: Insights into Family of Multifunctional Proteins and Peptides with Potential Therapeutical Applications A Gitlin-Domagalska, A Maciejewska, D Dębowski Pharmaceuticals 13 (12), 421, 2020 | 69 | 2020 |
Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors A Łęgowska, D Dębowski, A Lesner, M Wysocka, K Rolka Bioorganic & medicinal chemistry 17 (9), 3302-3307, 2009 | 54 | 2009 |
Conjugates of ciprofloxacin and levofloxacin with cell-penetrating peptide exhibit antifungal activity and mammalian cytotoxicity N Ptaszyńska, K Gucwa, K Olkiewicz, M Heldt, M Serocki, A Stupak, ... International journal of molecular sciences 21 (13), 4696, 2020 | 48 | 2020 |
Inhibitors of Matriptase‐2 Based on the Trypsin Inhibitor SFTI‐1 A Gitlin, D Dębowski, N Karna, A Łęgowska, M Stirnberg, M Gütschow, ... ChemBioChem 16 (11), 1601-1607, 2015 | 42 | 2015 |
Vasopressin and its analogues: from natural hormones to multitasking peptides M Glavaš, A Gitlin-Domagalska, D Dębowski, N Ptaszyńska, A Łęgowska, ... International journal of molecular sciences 23 (6), 3068, 2022 | 40 | 2022 |
Implication of the disulfide bridge in trypsin inhibitor SFTI-1 in its interaction with serine proteinases A Łęgowska, D Dębowski, R Łukajtis, M Wysocka, C Czaplewski, ... Bioorganic & medicinal chemistry 18 (23), 8188-8193, 2010 | 27 | 2010 |
Peptomeric analogues of trypsin inhibitor SFTI-1 isolated from sunflower seeds A Łęgowska, E Bulak, M Wysocka, A Jaśkiewicz, A Lesner, D Dębowski, ... Bioorganic & medicinal chemistry 16 (10), 5644-5652, 2008 | 27 | 2008 |
Antibiotic-Based Conjugates Containing Antimicrobial HLopt2 Peptide: Design, Synthesis, Antimicrobial and Cytotoxic Activities N Ptaszyńska, K Gucwa, K Olkiewicz, A Łęgowska, J Okońska, ... ACS Chem. Biol. 14 (10), 3060–3071, 2018 | 25 | 2018 |
Peptide conjugates of lactoferricin analogues and antimicrobials—Design, chemical synthesis, and evaluation of antimicrobial activity and mammalian cytotoxicity N Ptaszyńska, K Olkiewicz, J Okońska, K Gucwa, A Łęgowska, ... Peptides 117, 170079, 2019 | 23 | 2019 |
Inhibitory and antimicrobial activities of OGTI and HV-BBI peptides, fragments and analogs derived from amphibian skin D Dębowski, R Łukajtis, A Łęgowska, N Karna, M Pikuła, M Wysocka, ... Peptides 35 (2), 276-284, 2012 | 22 | 2012 |
Inhibition of human and yeast 20S proteasome by analogues of trypsin inhibitor SFTI-1 D Dębowski, M Pikuła, M Lubos, P Langa, P Trzonkowski, A Lesner, ... PloS one 9 (2), e89465, 2014 | 18 | 2014 |
Selection of peptomeric inhibitors of bovine α-chymotrypsin and cathepsin G based on trypsin inhibitor SFTI-1 using a combinatorial chemistry approach A Łęgowska, D Dębowski, A Lesner, M Wysocka, K Rolka Molecular diversity 14, 51-58, 2010 | 18 | 2010 |
Bladder cancer detection using a peptide substrate of the 20S proteasome N Gruba, M Wysocka, M Brzezińska, D Dębowski, M Sieńczyk, ... The FEBS journal 283 (15), 2929-2948, 2016 | 17 | 2016 |
Design and chemical syntheses of potent matriptase‐2 inhibitors based on trypsin inhibitor SFTI‐1 isolated from sunflower seeds A Gitlin‐Domagalska, D Dębowski, A Łęgowska, M Stirnberg, J Okońska, ... Peptide Science 108 (6), e23031, 2017 | 16 | 2017 |
Matriptase-2: monitoring and inhibiting its proteolytic activity A Gitlin-Domagalska, M Mangold, D Dębowski, N Ptaszyńska, ... Future medicinal chemistry 10 (23), 2745-2761, 2018 | 15 | 2018 |
Fluorescent analogs of trypsin inhibitor SFTI‐1 isolated from sunflower seeds—synthesis and applications A Lesner, N Karna, M Psurski, A Łęgowska, M Wysocka, K Guzow, ... Peptide Science 102 (1), 124-135, 2014 | 15 | 2014 |
Hybrid analogues of SFTI‐1 modified in P1 position by β‐ and γ‐amino acids and N‐substituted β‐alanines D Debowski, R Łukajtis, M Filipowicz, P Strzelecka, M Wysocka, ... Peptide Science 100 (2), 154-159, 2013 | 12 | 2013 |
Antimicrobial activity of chimera peptides composed of Human Neutrophil Peptide 1 (HNP-1) truncated analogues and Bovine Lactoferrampin N Ptaszyńska, K Gucwa, A Łęgowska, D Dębowski, ... Bioconjugate chemistry 29 (9), 3060-3071, 2018 | 11 | 2018 |
Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome N Gruba, M Wysocka, M Brzezińska, D Debowski, K Rolka, NI Martin, ... Analytical biochemistry 508, 38-45, 2016 | 10 | 2016 |
Noncovalent inhibitors of human 20S and 26S proteasome based on trypsin inhibitor SFTI‐1 D Dębowski, M Cichorek, M Lubos, S Wójcik, A Łęgowska, K Rolka Peptide Science 106 (5), 685-696, 2016 | 8 | 2016 |