| Novel tetrazole-based selective COX-2 inhibitors: Design, synthesis, anti-inflammatory activity, evaluation of PGE2, TNF-α, IL-6 and histopathological study MB Labib, AM Fayez, ELN EL-Shaymaa, M Awadallah, PA Halim Bioorganic Chemistry 104, 104308, 2020 | 52 | 2020 |
| Novel pyrazole-based COX-2 inhibitors as potential anticancer agents: Design, synthesis, cytotoxic effect against resistant cancer cells, cell cycle arrest, apoptosis induction … PA Halim, SMZ Sharkawi, MB Labib Bioorganic chemistry 131, 106273, 2023 | 28 | 2023 |
| Synthesis, and anti-proliferative, Pim-1 kinase inhibitors and molecular docking of thiophenes derived from estrone RM Mohareb, EM Samir, PA Halim Bioorganic Chemistry 83, 402-413, 2019 | 27 | 2019 |
| Recent updates on thienopyrimidine derivatives as anticancer agents MTM Sayed, RA Hassan, PA Halim, AK El-Ansary Medicinal Chemistry Research 32 (4), 659-681, 2023 | 25 | 2023 |
| Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer PA Halim, RA Hassan, KO Mohamed, SO Hassanin, MG Khalil, AM Abdou, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 189-201, 2022 | 24 | 2022 |
| Uses of cyclohexane-1, 3-dione for the synthesis of 1, 2, 4-triazine derivatives as anti-proliferative agents and tyrosine kinases inhibitors NYM Abdo, RM Mohareb, PA Halim Bioorganic Chemistry 97, 103667, 2020 | 20 | 2020 |
| Design, synthesis, anticancer evaluation, and in silico studies of some thieno[2,3‐d]pyrimidine derivatives as EGFR inhibitors MTM Sayed, PA Halim, AK El‐Ansary, RA Hassan Drug Development Research 84 (6), 1299-1319, 2023 | 10 | 2023 |
| Design, synthesis, antineoplastic activity of new pyrazolo [3, 4-d] pyrimidine derivatives as dual CDK2/GSK3β kinase inhibitors; molecular docking study, and ADME prediction MTM Nemr, A Elshewy, ML Ibrahim, AM El Kerdawy, PA Halim Bioorganic Chemistry 150, 107566, 2024 | 9 | 2024 |
| Design and synthesis of novel ibuprofen derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents: evaluation of PGE2, TNF-α, IL-6 and histopathological … PA Halim, HB El-Nassan, YS El-Dash Medicinal Chemistry 18 (4), 427-443, 2022 | 9 | 2022 |
| Design and synthesis of novel 4-fluorobenzamide-based derivatives as promising anti-inflammatory and analgesic agents with an enhanced gastric tolerability and COX-inhibitory … PA Halim, HH Georgey, MY George, AM El Kerdawy, MF Said Bioorganic Chemistry 115, 105253, 2021 | 9 | 2021 |
| Uses of Anthranilic Acid for the Synthesis of Dihydroquinazolin Derivatives with Antitumor, Antiproliferative and Pim-1 kinase Activities. RM Mohareb, PA Halim Acta Chimica Slovenica 65 (3), 2018 | 7 | 2018 |
| Advances in structural identification of some thieno [2, 3-d] pyrimidine scaffolds as antitumor molecules: Synthetic approaches and control programmed cancer cell death potential AES Mghwary, RA Hassan, PA Halim, MK Abdelhameid Bioorganic Chemistry, 107985, 2024 | | 2024 |
