The JAK-inhibitor ruxolitinib impairs dendritic cell function in vitro and in vivo A Heine, SAE Held, SN Daecke, S Wallner, SP Yajnanarayana, C Kurts, ... Blood, The Journal of the American Society of Hematology 122 (7), 1192-1202, 2013 | 400 | 2013 |
G-quadruplexes: a promising target for cancer therapy N Kosiol, S Juranek, P Brossart, A Heine, K Paeschke Molecular Cancer 20, 1-18, 2021 | 396 | 2021 |
Intradermal vaccinations with RNA coding for TAA generate CD8+ and CD4+ immune responses and induce clinical benefit in vaccinated patients SM Rittig, M Haentschel, KJ Weimer, A Heine, MR Muller, W Brugger, ... Molecular Therapy 19 (5), 990-999, 2011 | 263 | 2011 |
Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal T Baumann, A Dunkel, C Schmid, S Schmitt, M Hiltensperger, K Lohr, ... Nature immunology 21 (5), 555-566, 2020 | 215 | 2020 |
Processing and presentation of HLA class I and II epitopes by dendritic cells after transfection with in vitro–transcribed MUC1 RNA D Dörfel, S Appel, F Grünebach, MM Weck, MR Müller, A Heine, ... Blood 105 (8), 3199-3205, 2005 | 210 | 2005 |
JAK inhibition impairs NK cell function in myeloproliferative neoplasms K Schönberg, J Rudolph, M Vonnahme, S Parampalli Yajnanarayana, ... Cancer research 75 (11), 2187-2199, 2015 | 192 | 2015 |
JAK1/2 inhibition impairs T cell function in vitro and in patients with myeloproliferative neoplasms S Parampalli Yajnanarayana, T Stübig, I Cornez, H Alchalby, ... British journal of haematology 169 (6), 824-833, 2015 | 179 | 2015 |
Ruxolitinib is a potent immunosuppressive compound: is it time for anti-infective prophylaxis? A Heine, P Brossart, D Wolf Blood, The Journal of the American Society of Hematology 122 (23), 3843-3844, 2013 | 175 | 2013 |
Clinical and immunological effects of mRNA vaccines in malignant diseases A Heine, S Juranek, P Brossart Molecular cancer 20, 1-20, 2021 | 130 | 2021 |
MicroRNA-146a reduces MHC-II expression via targeting JAK/STAT signaling in dendritic cells after stem cell transplantation N Stickel, K Hanke, D Marschner, G Prinz, M Köhler, W Melchinger, ... Leukemia 31 (12), 2732-2741, 2017 | 109 | 2017 |
Matrilysin (MMP-7) Is a Novel Broadly Expressed Tumor Antigen Recognized by Antigen-Specific T Cells Y Yokoyama, F Grünebach, SM Schmidt, A Heine, M Häntschel, ... Clinical Cancer Research 14 (17), 5503-5511, 2008 | 108 | 2008 |
Diffuse myocardial inflammation in COVID-19 associated myocarditis detected by multiparametric cardiac magnetic resonance imaging JA Luetkens, A Isaak, S Zimmer, J Nattermann, AM Sprinkart, C Boesecke, ... Circulation: Cardiovascular Imaging 13 (5), e010897, 2020 | 102 | 2020 |
CCAAT/enhancer-binding proteins α and β negatively influence the capacity of tumor necrosis factor α to up-regulate the human cytomegalovirus IE1/2 enhancer/promoter by nuclear … S Prösch, AK Heine, HD Volk, DH Krüger Journal of biological chemistry 276 (44), 40712-40720, 2001 | 83 | 2001 |
Immunomodulatory effects of anti-angiogenic drugs A Heine, SAE Held, A Bringmann, TAW Holderried, P Brossart Leukemia 25 (6), 899-905, 2011 | 79 | 2011 |
RNA vaccines in cancer treatment A Bringmann, SAE Held, A Heine, P Brossart BioMed Research International 2010 (1), 623687, 2010 | 77 | 2010 |
C reactive protein flare predicts response to checkpoint inhibitor treatment in non-small cell lung cancer N Klümper, J Saal, F Berner, C Lichtensteiger, N Wyss, A Heine, ... Journal for Immunotherapy of Cancer 10 (3), 2022 | 67 | 2022 |
Long-term survival correlates with immunological responses in renal cell carcinoma patients treated with mRNA-based immunotherapy SM Rittig, M Haentschel, KJ Weimer, A Heine, MR Müller, W Brugger, ... Oncoimmunology 5 (5), e1108511, 2016 | 64 | 2016 |
Optimized Ki-67 staining in murine cells: a tool to determine cell proliferation C Graefe, L Eichhorn, P Wurst, J Kleiner, A Heine, I Panetas, Z Abdulla, ... Molecular biology reports 46, 4631-4643, 2019 | 59 | 2019 |
Development of hemolytic anemia in a nivolumab-treated patient with refractory metastatic squamous cell skin cancer and chronic lymphatic leukemia KS Schwab, A Heine, T Weimann, G Kristiansen, P Brossart Case Reports in Oncology 9 (2), 373-378, 2016 | 56 | 2016 |
The relevance of G-quadruplexes for DNA repair R Linke, M Limmer, SA Juranek, A Heine, K Paeschke International Journal of Molecular Sciences 22 (22), 12599, 2021 | 53 | 2021 |