Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations V Sequeira, PJM Wijnker, LLAM Nijenkamp, DWD Kuster, A Najafi, ... Circulation research 112 (11), 1491-1505, 2013 | 224 | 2013 |
The physiological role of cardiac cytoskeleton and its alterations in heart failure V Sequeira, LLAM Nijenkamp, JA Regan, J Van Der Velden Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (2), 700-722, 2014 | 223 | 2014 |
Historical perspective on heart function: the Frank–Starling Law V Sequeira, J van der Velden Biophysical reviews 7, 421-447, 2015 | 134 | 2015 |
β‐adrenergic receptor signalling and its functional consequences in the diseased heart A Najafi, V Sequeira, DWD Kuster, J van der Velden European journal of clinical investigation 46 (4), 362-374, 2016 | 133 | 2016 |
Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy ER Witjas-Paalberends, N Piroddi, K Stam, SJ Van Dijk, VS Oliviera, ... Cardiovascular research 99 (3), 432-441, 2013 | 130 | 2013 |
Metabolic changes in hypertrophic cardiomyopathies: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology J Van Der Velden, CG Tocchetti, G Varricchi, A Bianco, V Sequeira, ... Cardiovascular research 114 (10), 1273-1280, 2018 | 94 | 2018 |
Hypertrophic cardiomyopathy: a vicious cycle triggered by sarcomere mutations and secondary disease hits PJM Wijnker, V Sequeira, DWD Kuster, J Velden Antioxidants & redox signaling 31 (4), 318-358, 2019 | 86 | 2019 |
Synergistic role of ADP and Ca2+ in diastolic myocardial stiffness V Sequeira, A Najafi, M McConnell, ED Fowler, IAE Bollen, RCI Wüst, ... The Journal of physiology 593 (17), 3899-3916, 2015 | 79 | 2015 |
GSK3β phosphorylates newly identified site in the proline-alanine–rich region of cardiac myosin–binding protein C and alters cross-bridge cycling kinetics in human DWD Kuster, V Sequeira, A Najafi, NM Boontje, PJM Wijnker, ... Circulation research 112 (4), 633-639, 2013 | 67 | 2013 |
The Frank–Starling Law: a jigsaw of titin proportions V Sequeira, J van der Velden Biophysical reviews 9, 259-267, 2017 | 64 | 2017 |
Length-dependent activation is modulated by cardiac troponin I bisphosphorylation at Ser23 and Ser24 but not by Thr143 phosphorylation PJM Wijnker, V Sequeira, DB Foster, Y Li, CG Dos Remedios, AM Murphy, ... American Journal of Physiology-Heart and Circulatory Physiology 306 (8 …, 2014 | 54 | 2014 |
The CaMKII inhibitor KN93-calmodulin interaction and implications for calmodulin tuning of NaV1. 5 and RyR2 function CN Johnson, R Pattanayek, F Potet, RT Rebbeck, DJ Blackwell, ... Cell Calcium 82, 102063, 2019 | 51 | 2019 |
ADP-stimulated contraction: a predictor of thin-filament activation in cardiac disease V Sequeira, A Najafi, PJM Wijnker, CG Dos Remedios, M Michels, ... Proceedings of the National Academy of Sciences 112 (50), E7003-E7012, 2015 | 48 | 2015 |
Distinctive patterns of inflammation across the heart failure syndrome GG Schiattarella, V Sequeira, P Ameri Heart failure reviews 26, 1333-1344, 2021 | 47 | 2021 |
Energetic drain driving hypertrophic cardiomyopathy V Sequeira, E Bertero, C Maack FEBS letters 593 (13), 1616-1626, 2019 | 47 | 2019 |
Loss of Mitochondrial Ca2+ Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy E Bertero, A Nickel, M Kohlhaas, M Hohl, V Sequeira, C Brune, ... Circulation 144 (21), 1694-1713, 2021 | 43 | 2021 |
CaMKII does not control mitochondrial Ca2+ uptake in cardiac myocytes AG Nickel, M Kohlhaas, E Bertero, D Wilhelm, M Wagner, V Sequeira, ... The Journal of physiology 598 (7), 1361-1376, 2020 | 43 | 2020 |
Selective phosphorylation of PKA targets after β-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model A Najafi, V Sequeira, M Helmes, IAE Bollen, M Goebel, JA Regan, ... Cardiovascular research 110 (2), 200-214, 2016 | 37 | 2016 |
PKCα-specific phosphorylation of the troponin complex in human myocardium: a functional and proteomics analysis V Kooij, P Zhang, SR Piersma, V Sequeira, NM Boontje, PJM Wijnker, ... PloS one 8 (10), e74847, 2013 | 36 | 2013 |
Cardiac myosin-binding protein C: hypertrophic cardiomyopathy mutations and structure–function relationships V Sequeira, ER Witjas-Paalberends, DWD Kuster, J van der Velden Pflügers Archiv-European Journal of Physiology 466, 201-206, 2014 | 33 | 2014 |