| Single-cell NF-κB dynamics reveal digital activation and analogue information processing S Tay, JJ Hughey, TK Lee, T Lipniacki, SR Quake, MW Covert Nature 466 (7303), 267-271, 2010 | 1001 | 2010 |
| High-sensitivity measurements of multiple kinase activities in live single cells S Regot, JJ Hughey, BT Bajar, S Carrasco, MW Covert Cell 157 (7), 1724-1734, 2014 | 599 | 2014 |
| Guidelines for genome-scale analysis of biological rhythms ME Hughes, KC Abruzzi, R Allada, R Anafi, AB Arpat, G Asher, P Baldi, ... Journal of biological rhythms 32 (5), 380-393, 2017 | 263 | 2017 |
| Phenotype risk scores identify patients with unrecognized Mendelian disease patterns L Bastarache, JJ Hughey, S Hebbring, J Marlo, W Zhao, WT Ho, ... Science 359 (6381), 1233-1239, 2018 | 215 | 2018 |
| A noisy paracrine signal determines the cellular NF-κB response to lipopolysaccharide TK Lee, EM Denny, JC Sanghvi, JE Gaston, ND Maynard, JJ Hughey, ... Science signaling 2 (93), ra65-ra65, 2009 | 192 | 2009 |
| Microfluidic platform for real-time signaling analysis of multiple single T cells in parallel S Faley, K Seale, J Hughey, DK Schaffer, S VanCompernolle, B McKinney, ... Lab on a Chip 8 (10), 1700-1712, 2008 | 179 | 2008 |
| Releasing a preprint is associated with more attention and citations for the peer-reviewed article DY Fu, JJ Hughey Elife 8, e52646, 2019 | 156 | 2019 |
| Robust meta-analysis of gene expression using the elastic net JJ Hughey, AJ Butte Nucleic Acids Research 43 (12), e79, 2015 | 143 | 2015 |
| Population-level rhythms in human skin with implications for circadian medicine G Wu, MD Ruben, RE Schmidt, LJ Francey, DF Smith, RC Anafi, ... Proceedings of the National Academy of Sciences 115 (48), 12313-12318, 2018 | 129 | 2018 |
| Live-cell measurements of kinase activity in single cells using translocation reporters T Kudo, S Jeknić, DN Macklin, S Akhter, JJ Hughey, S Regot, MW Covert Nature protocols 13 (1), 155-169, 2018 | 126 | 2018 |
| ZeitZeiger: supervised learning for high-dimensional data from an oscillatory system JJ Hughey, T Hastie, AJ Butte Nucleic acids research 44 (8), e80-e80, 2016 | 108 | 2016 |
| Evidence for widespread dysregulation of circadian clock progression in human cancer J Shilts, G Chen, JJ Hughey PeerJ 6, e4327, 2018 | 97 | 2018 |
| LimoRhyde: a flexible approach for differential analysis of rhythmic transcriptome data JM Singer, JJ Hughey Journal of biological rhythms 34 (1), 5-18, 2019 | 79 | 2019 |
| Computational modeling of mammalian signaling networks JJ Hughey, TK Lee, MW Covert Wiley Interdisciplinary Reviews: Systems Biology and Medicine 2 (2), 194-209, 2010 | 78 | 2010 |
| Machine learning identifies a compact gene set for monitoring the circadian clock in human blood JJ Hughey Genome medicine 9, 1-11, 2017 | 75 | 2017 |
| NF-κB signaling dynamics is controlled by a dose-sensing autoregulatory loop MM DeFelice, HR Clark, JJ Hughey, I Maayan, T Kudo, MV Gutschow, ... Science signaling 12 (579), eaau3568, 2019 | 61 | 2019 |
| Single-cell variation leads to population invariance in NF-κB signaling dynamics JJ Hughey, MV Gutschow, BT Bajar, MW Covert Molecular biology of the cell 26 (3), 583-590, 2015 | 60 | 2015 |
| Self-reported dietary adherence, disease-specific symptoms, and quality of life are associated with healthcare provider follow-up in celiac disease JJ Hughey, BK Ray, AR Lee, KN Voorhees, CP Kelly, D Schuppan BMC gastroenterology 17, 1-8, 2017 | 55 | 2017 |
| MetaCyto: a tool for automated meta-analysis of mass and flow cytometry data Z Hu, C Jujjavarapu, JJ Hughey, S Andorf, HC Lee, PF Gherardini, ... Cell reports 24 (5), 1377-1388, 2018 | 53 | 2018 |
| Eating breakfast and avoiding late-evening snacking sustains lipid oxidation KP Kelly, OP McGuinness, M Buchowski, JJ Hughey, H Chen, J Powers, ... PLoS biology 18 (2), e3000622, 2020 | 52 | 2020 |
