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WAF1/CIP1 Is Induced in p53-mediated G1 Arrest and Apoptosis WS El-Deiry, JW Harper, PM O'Connor, VE Velculescu, CE Canman, ... Cancer research 54 (5), 1169-1174, 1994 | 3026 | 1994 |
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control C Deng, P Zhang, JW Harper, SJ Elledge, P Leder Cell 82 (4), 675-684, 1995 | 2818 | 1995 |
A map of the interactome network of the metazoan C. elegans S Li, CM Armstrong, N Bertin, H Ge, S Milstein, M Boxem, PO Vidalain, ... Science 303 (5657), 540-543, 2004 | 2205 | 2004 |
The DNA damage response: ten years after JW Harper, SJ Elledge Molecular cell 28 (5), 739-745, 2007 | 2183 | 2007 |
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest V Dulić, WK Kaufmann, SJ Wilson, TD Tisty, E Lees, JW Harper, ... Cell 76 (6), 1013-1023, 1994 | 1982 | 1994 |
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box C Bai, P Sen, K Hofmann, L Ma, M Goebl, JW Harper, SJ Elledge Cell 86 (2), 263-274, 1996 | 1872 | 1996 |
Systematic and quantitative assessment of the ubiquitin-modified proteome W Kim, EJ Bennett, EL Huttlin, A Guo, J Li, A Possemato, ME Sowa, ... Molecular cell 44 (2), 325-340, 2011 | 1843 | 2011 |
Network organization of the human autophagy system C Behrends, ME Sowa, SP Gygi, JW Harper Nature 466 (7302), 68-76, 2010 | 1772 | 2010 |
Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex N Zheng, BA Schulman, L Song, JJ Miller, PD Jeffrey, P Wang, C Chu, ... Nature 416 (6882), 703-709, 2002 | 1769 | 2002 |
Defining the human deubiquitinating enzyme interaction landscape ME Sowa, EJ Bennett, SP Gygi, JW Harper Cell 138 (2), 389-403, 2009 | 1719 | 2009 |
Molecular definitions of autophagy and related processes L Galluzzi, EH Baehrecke, A Ballabio, P Boya, JM Bravo‐San Pedro, ... The EMBO journal 36 (13), 1811-1836, 2017 | 1706 | 2017 |
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy JD Mancias, X Wang, SP Gygi, JW Harper, AC Kimmelman Nature 509 (7498), 105-109, 2014 | 1663 | 2014 |
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex D Skowyra, KL Craig, M Tyers, SJ Elledge, JW Harper Cell 91 (2), 209-219, 1997 | 1577 | 1997 |
The BioPlex network: a systematic exploration of the human interactome EL Huttlin, L Ting, RJ Bruckner, F Gebreab, MP Gygi, J Szpyt, S Tam, ... Cell 162 (2), 425-440, 2015 | 1534 | 2015 |
Architecture of the human interactome defines protein communities and disease networks EL Huttlin, RJ Bruckner, JA Paulo, JR Cannon, L Ting, K Baltier, G Colby, ... Nature 545 (7655), 505-509, 2017 | 1501 | 2017 |
Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle A Koff, A Giordano, D Desai, K Yamashita, JW Harper, S Elledge, ... Science 257 (5077), 1689-1694, 1992 | 1461 | 1992 |
Inhibition of cyclin-dependent kinases by p21. JW Harper, SJ Elledge, K Keyomarsi, B Dynlacht, LH Tsai, P Zhang, ... Molecular biology of the cell 6 (4), 387-400, 1995 | 1408 | 1995 |
p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene. S Matsuoka, MC Edwards, C Bai, S Parker, P Zhang, A Baldini, JW Harper, ... Genes & development 9 (6), 650-662, 1995 | 1367 | 1995 |