Liver-type glutaminase GLS2 is a druggable metabolic node in luminal-subtype breast cancer MJ Lukey, AA Cluntun, WP Katt, JL Miao-chong, JE Druso, ... Cell reports 29 (1), 76-88. e7, 2019 | 102 | 2019 |
Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus JA Baccile, JE Spraker, HH Le, E Brandenburger, C Gomez, JW Bok, ... Nature chemical biology 12 (6), 419-424, 2016 | 91 | 2016 |
The chemical biology of hydropersulfides (RSSH): Chemical stability, reactivity and redox roles SS Saund, V Sosa, S Henriquez, QNN Nguyen, CL Bianco, S Soeda, ... Archives of biochemistry and biophysics 588, 15-24, 2015 | 81 | 2015 |
Characterization of interactions of dietary cholesterol with the murine and human gut microbiome HH Le, MT Lee, KR Besler, JMC Comrie, EL Johnson Nature microbiology 7 (9), 1390-1403, 2022 | 72 | 2022 |
Host hepatic metabolism is modulated by gut microbiota-derived sphingolipids HH Le, MT Lee, KR Besler, EL Johnson Cell host & microbe 30 (6), 798-808. e7, 2022 | 60 | 2022 |
Dietary sphinganine is selectively assimilated by members of the mammalian gut microbiome MT Lee, HH Le, EL Johnson Journal of lipid research 62, 2021 | 46 | 2021 |
Biosynthesis of Modular Ascarosides in C. elegans O Panda, AE Akagi, AB Artyukhin, JC Judkins, HH Le, P Mahanti, ... Angewandte Chemie 129 (17), 4807-4811, 2017 | 46 | 2017 |
Linking genomic and metabolomic natural variation uncovers nematode pheromone biosynthesis JM Falcke, N Bose, AB Artyukhin, C Rödelsperger, GV Markov, JJ Yim, ... Cell chemical biology 25 (6), 787-796. e12, 2018 | 44 | 2018 |
Characterization of inositol lipid metabolism in gut-associated Bacteroidetes SL Heaver, HH Le, P Tang, A Baslé, C Mirretta Barone, DL Vu, JL Waters, ... Nature microbiology 7 (7), 986-1000, 2022 | 36 | 2022 |
Diketopiperazine formation in fungi requires dedicated cyclization and thiolation domains JA Baccile, HH Le, BT Pfannenstiel, JW Bok, C Gomez, E Brandenburger, ... Angewandte Chemie International Edition 58 (41), 14589-14593, 2019 | 36 | 2019 |
Deep interrogation of metabolism using a pathway-targeted click-chemistry approach JS Hoki, HH Le, KE Mellott, YK Zhang, BW Fox, PR Rodrigues, Y Yu, ... Journal of the American Chemical Society 142 (43), 18449-18459, 2020 | 25 | 2020 |
Modular metabolite assembly in Caenorhabditis elegans depends on carboxylesterases and formation of lysosome-related organelles HH Le, CJJ Wrobel, SM Cohen, J Yu, H Park, MJ Helf, BJ Curtis, ... Elife 9, e61886, 2020 | 23 | 2020 |
Identification of Uric Acid Gluconucleoside–Ascaroside Conjugates in Caenorhabditis elegans by Combining Synthesis and MicroED BJ Curtis, LJ Kim, CJJ Wrobel, JM Eagan, RA Smith, JE Burch, HH Le, ... Organic letters 22 (17), 6724-6728, 2020 | 23 | 2020 |
Parallel pathways for serotonin biosynthesis and metabolism in C. elegans J Yu, MC Vogt, BW Fox, CJJ Wrobel, D Fajardo Palomino, BJ Curtis, ... Nature chemical biology 19 (2), 141-150, 2023 | 22 | 2023 |
Identification and characterization of 3-ketosphinganine reductase activity encoded at the BT_0972 locus in Bacteroides thetaiotaomicron MT Lee, HH Le, KR Besler, EL Johnson Journal of lipid research 63 (7), 2022 | 14 | 2022 |
Going Keto? Say ΒHB-Ye Bye to Your Gut Bifidobacteria HH Le, EL Johnson Cell Host & Microbe 28 (1), 3-5, 2020 | 9 | 2020 |
Nucleotide spin labeling for ESR spectroscopy of ATP-binding proteins AR Muok, TK Chua, H Le, BR Crane Applied magnetic resonance 49 (12), 1385-1395, 2018 | 9 | 2018 |
An untargeted approach for revealing electrophilic metabolites Y Yu, HH Le, BJ Curtis, CJJ Wrobel, B Zhang, DN Maxwell, JY Pan, ... ACS chemical biology 15 (11), 3030-3037, 2020 | 6 | 2020 |
Prevotella copri variants among a single host diverge in sphingolipid production X Xiao, HH Le, MT Lee, D Lamm, EL Johnson, IL Brito Mbio 15 (2), e02409-23, 2024 | 3 | 2024 |
Gut bacterial sphingolipid production modulates dysregulated skin lipid homeostasis MT Lee, X Tan, H Le, K Besler, S Thompson, TA Harris-Tryon, E Johnson bioRxiv, 2024.12. 29.629238, 2024 | | 2024 |