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Bradly Wouters
Bradly Wouters
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Bestätigte E-Mail-Adresse bei uhn.ca
Titel
Zitiert von
Zitiert von
Jahr
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ...
Autophagy 8 (4), 445-544, 2012
13916*2012
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study
F Pagès, B Mlecnik, F Marliot, G Bindea, FS Ou, C Bifulco, A Lugli, ...
The Lancet 391 (10135), 2128-2139, 2018
20082018
Towards the introduction of the ‘Immunoscore’in the classification of malignant tumours
J Galon, B Mlecnik, G Bindea, HK Angell, A Berger, C Lagorce, A Lugli, ...
The Journal of pathology 232 (2), 199-209, 2014
15842014
Hypoxia signalling through mTOR and the unfolded protein response in cancer
BG Wouters, M Koritzinsky
Nature Reviews Cancer 8 (11), 851-864, 2008
10852008
Cancer classification using the Immunoscore: a worldwide task force
J Galon, F Pagès, FM Marincola, HK Angell, M Thurin, A Lugli, I Zlobec, ...
Journal of translational medicine 10, 1-10, 2012
10042012
Apoptosis, p53, and tumor cell sensitivity to anticancer agents
JM Brown, BG Wouters
Cancer research 59 (7), 1391-1399, 1999
9941999
ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
M Bi, C Naczki, M Koritzinsky, D Fels, J Blais, N Hu, H Harding, I Novoa, ...
The EMBO journal 24 (19), 3470-3481, 2005
9332005
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
KMA Rouschop, T van den Beucken, L Dubois, H Niessen, J Bussink, ...
The Journal of clinical investigation 120 (1), 127-141, 2010
9292010
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α
C Koumenis, C Naczki, M Koritzinsky, S Rastani, A Diehl, N Sonenberg, ...
Molecular and cellular biology 22 (21), 7405-7416, 2002
8742002
Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells
TN Seagroves, HE Ryan, H Lu, BG Wouters, M Knapp, P Thibault, ...
Molecular and cellular biology, 2001
7932001
Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis
JC Sluimer, JM Gasc, JL van Wanroij, N Kisters, M Groeneweg, ...
Journal of the American College of Cardiology 51 (13), 1258-1265, 2008
5442008
Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and-Independent Mechanisms and Contributes to Drug Resistance
JT Erler, CJ Cawthorne, KJ Williams, M Koritzinsky, BG Wouters, C Wilson, ...
Molecular and Cellular Biology 24 (7), 2875-2889, 2004
5392004
Activating transcription factor 4 is translationally regulated by hypoxic stress
JD Blais, V Filipenko, M Bi, HP Harding, D Ron, C Koumenis, BG Wouters, ...
Molecular and cellular biology 24 (17), 7469-7482, 2004
5282004
Cells at intermediate oxygen levels can be more important than the" hypoxic fraction" in determining tumor response to fractionated radiotherapy
BG Wouters, JM Brown
Radiation research 147 (5), 541-550, 1997
4331997
Time between the first day of chemotherapy and the last day of chest radiation is the most important predictor of survival in limited-disease small-cell lung cancer
D De Ruysscher, M Pijls-Johannesma, SM Bentzen, A Minken, ...
Journal of Clinical Oncology 24 (7), 1057-1063, 2006
4282006
Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control
M Koritzinsky, MG Magagnin, T van den Beucken, R Seigneuric, ...
The EMBO journal 25 (5), 1114-1125, 2006
4172006
The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
P van Galen, A Kreso, N Mbong, DG Kent, T Fitzmaurice, JE Chambers, ...
Nature 510 (7504), 268-272, 2014
3872014
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance
N Chan, M Koritzinsky, H Zhao, R Bindra, PM Glazer, S Powell, ...
Cancer research 68 (2), 605-614, 2008
3712008
Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response
VE Zannella, A Dal Pra, H Muaddi, TD McKee, S Stapleton, J Sykes, ...
Clinical cancer research 19 (24), 6741-6750, 2013
3372013
“Translating” tumor hypoxia: Unfolded protein response (UPR)–dependent and UPR-independent pathways
C Koumenis, BG Wouters
Molecular Cancer Research 4 (7), 423-436, 2006
2882006
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