LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer Y Wang, H Zhang, Y Chen, Y Sun, F Yang, W Yu, J Liang, L Sun, X Yang, ... Cell 138 (4), 660-672, 2009 | 796 | 2009 |
The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer Y Chen, L Shi, L Zhang, R Li, J Liang, W Yu, L Sun, X Yang, Y Wang, ... Journal of Biological Chemistry 283 (26), 17969-17978, 2008 | 475 | 2008 |
Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells B Shi, J Liang, X Yang, Y Wang, Y Zhao, H Wu, L Sun, Y Zhang, Y Chen, ... Molecular and cellular biology 27 (14), 5105-5119, 2007 | 393 | 2007 |
Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis H Wu, Y Chen, J Liang, B Shi, G Wu, Y Zhang, D Wang, R Li, X Yi, ... Nature 438 (7070), 981, 2005 | 382 | 2005 |
Emergence of a high-plasticity cell state during lung cancer evolution ND Marjanovic, M Hofree, JE Chan, D Canner, K Wu, M Trakala, ... Cancer Cell 38 (2), 229-246. e13, 2020 | 322 | 2020 |
An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression Y Qin, JD Roberts, SA Grimm, FB Lih, LJ Deterding, R Li, K Chrysovergis, ... Genome Biology 19 (1), 7, 2018 | 157 | 2018 |
hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signaling X Wang, K Chrysovergis, J Kosak, G Kissling, M Streicker, G Moser, R Li, ... Aging (Albany NY) 6 (8), 690, 2014 | 115 | 2014 |
Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity JM Freudenberg, S Ghosh, BL Lackford, S Yellaboina, X Zheng, R Li, ... Nucleic acids research 40 (8), 3364-3377, 2011 | 108 | 2011 |
Coordinated regulation of AIB1 transcriptional activity by sumoylation and phosphorylation H Wu, L Sun, Y Zhang, Y Chen, B Shi, R Li, Y Wang, J Liang, D Fan, G Wu, ... Journal of Biological Chemistry 281 (31), 21848-21856, 2006 | 108 | 2006 |
The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor‐regulated transcription H Zhang, L Sun, J Liang, W Yu, Y Zhang, Y Wang, Y Chen, R Li, X Sun, ... The EMBO journal 25 (18), 4223-4233, 2006 | 102 | 2006 |
JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation L Sun, L Shi, W Li, W Yu, J Liang, H Zhang, X Yang, Y Wang, R Li, X Yao, ... Proceedings of the National Academy of Sciences 106 (25), 10195-10200, 2009 | 96 | 2009 |
Obesity, rather than diet, drives epigenomic alterations in colonic epithelium resembling cancer progression R Li, SA Grimm, K Chrysovergis, J Kosak, X Wang, Y Du, A Burkholder, ... Cell metabolism 19 (4), 702-711, 2014 | 74 | 2014 |
Transcriptome and DNA Methylome Analysis in a Mouse Model of Diet-Induced Obesity Predicts Increased Risk of Colorectal Cancer R Li, SA Grimm, D Mav, H Gu, D Djukovic, R Shah, BA Merrick, D Raftery, ... Cell reports 22 (3), 624-637, 2018 | 69 | 2018 |
ZIP: a novel transcription repressor, represses EGFR oncogene and suppresses breast carcinogenesis R Li, H Zhang, W Yu, Y Chen, B Gui, J Liang, Y Wang, L Sun, X Yang, ... The EMBO journal 28 (18), 2763-2776, 2009 | 64 | 2009 |
DNA methylation and transcriptome aberrations mediated by ERα in mouse seminal vesicles following developmental DES exposure Y Li, KJ Hamilton, T Wang, LA Coons, WN Jefferson, R Li, Y Wang, ... Proceedings of the National Academy of Sciences 115 (18), E4189-E4198, 2018 | 25 | 2018 |
Fine-tuning of epigenetic regulation with respect to promoter CpG content in a cell type-specific manner R Li, D Mav, SA Grimm, R Jothi, R Shah, PA Wade epigenetics 9 (5), 747-759, 2014 | 16 | 2014 |
sZIP, an alternative splice variant of ZIP, antagonizes transcription repression and growth inhibition by ZIP W Yu, R Li, B Gui, Y Shang Journal of Biological Chemistry 285 (19), 14301-14307, 2010 | 14 | 2010 |
CUT&Tag-BS for simultaneous profiling of histone modification and DNA methylation with high efficiency and low cost R Li, SA Grimm, PA Wade Cell Reports Methods, 100118, 2021 | 12 | 2021 |
Prognostic and therapeutic significance of COP9 signalosome subunit CSN5 in prostate cancer YZ Mazzu, YR Liao, S Nandakumar, LE Jehane, RP Koche, SH Rajanala, ... Oncogene, 1-12, 2021 | 10 | 2021 |
Low-input ATAC&mRNA-seq protocol for simultaneous profiling of chromatin accessibility and gene expression R Li, SA Grimm, PA Wade STAR protocols 2 (3), 100764, 2021 | 5 | 2021 |