| Rac signaling in breast cancer: a tale of GEFs and GAPs E Wertheimer, A Gutierrez-Uzquiza, C Rosemblit, C Lopez-Haber, ... Cellular signalling 24 (2), 353-362, 2012 | 234 | 2012 |
| ARAF recurrent mutation causes central conducting lymphatic anomaly treatable with a MEK inhibitor D Li, ME March, A Gutierrez-Uzquiza, C Kao, C Seiler, E Pinto, ... Nature medicine 25 (7), 1116-1122, 2019 | 192 | 2019 |
| p38α mediates cell survival in response to oxidative stress via induction of antioxidant genes: effect on the p70S6K pathway Á Gutiérrez-Uzquiza, M Arechederra, P Bragado, JA Aguirre-Ghiso, ... Journal of Biological Chemistry 287 (4), 2632-2642, 2012 | 157 | 2012 |
| Pathogenic variant in EPHB4 results in central conducting lymphatic anomaly D Li, TL Wenger, C Seiler, ME March, A Gutierrez-Uzquiza, C Kao, E Bhoj, ... Human molecular genetics 27 (18), 3233-3245, 2018 | 95 | 2018 |
| Negative regulation of Akt activity by p38α MAP kinase in cardiomyocytes involves membrane localization of PP2A through interaction with caveolin-1 S Zuluaga, A Álvarez-Barrientos, A Gutiérrez-Uzquiza, M Benito, ... Cellular signalling 19 (1), 62-74, 2007 | 84 | 2007 |
| RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation N Zhou, A Gutierrez-Uzquiza, XY Zheng, R Chang, DT Vogl, AL Garfall, ... Leukemia 33 (8), 2006-2021, 2019 | 62 | 2019 |
| Met signaling in cardiomyocytes is required for normal cardiac function in adult mice M Arechederra, R Carmona, M González-Nuñez, Á Gutiérrez-Uzquiza, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (12 …, 2013 | 46 | 2013 |
| PKCϵ is an essential mediator of prostate cancer bone metastasis A Gutierrez-Uzquiza, C Lopez-Haber, DL Jernigan, A Fatatis, ... Molecular Cancer Research 13 (9), 1336-1346, 2015 | 45 | 2015 |
| C3G down-regulates p38 MAPK activity in response to stress by Rap-1 independent mechanisms: Involvement in cell death Á Gutiérrez-Uzquiza, M Arechederra, I Molina, R Baños, V Maia, M Benito, ... Cellular signalling 22 (3), 533-542, 2010 | 45 | 2010 |
| Cancer-associated fibroblasts in breast cancer treatment response and metastasis P Fernández-Nogueira, G Fuster, Á Gutierrez-Uzquiza, P Gascón, ... Cancers 13 (13), 3146, 2021 | 43 | 2021 |
| Transcriptional regulation of oncogenic protein kinase Cϵ (PKCϵ) by STAT1 and Sp1 proteins HB Wang, A Gutierrez-Uzquiza, R Garg, L Barrio-Real, MB Abera, ... Journal of Biological Chemistry 289 (28), 19823-19838, 2014 | 39 | 2014 |
| Biological and mechanical synergies to deal with proton therapy pitfalls: minibeams, FLASH, arcs, and gantryless rooms A Mazal, JA Vera Sanchez, D Sanchez-Parcerisa, JM Udias, S España, ... Frontiers in Oncology 10, 613669, 2021 | 38 | 2021 |
| C3G silencing enhances STI-571-induced apoptosis in CML cells through p38 MAPK activation, but it antagonizes STI-571 inhibitory effect on survival V Maia, M Sanz, J Gutierrez-Berzal, A de Luis, A Gutierrez-Uzquiza, ... Cellular signalling 21 (7), 1229-1235, 2009 | 37 | 2009 |
| C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms N Priego, M Arechederra, C Sequera, P Bragado, A Vázquez-Carballo, ... Oncotarget 7 (29), 45060, 2016 | 36 | 2016 |
| p38 MAPK down-regulates fibulin 3 expression through methylation of gene regulatory sequences: role in migration and invasion M Arechederra, N Priego, A Vázquez-Carballo, C Sequera, ... Journal of Biological Chemistry 290 (7), 4383-4397, 2015 | 33 | 2015 |
| p38α MAPK can positively or negatively regulate Rac-1 activity depending on the presence of serum S Zuluaga, A Gutiérrez-Uzquiza, P Bragado, A Álvarez-Barrientos, ... FEBS letters 581 (20), 3819-3825, 2007 | 28 | 2007 |
| Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol A Gutierrez-Uzquiza, F Colon-Gonzalez, TA Leonard, BJ Canagarajah, ... Nature communications 4 (1), 1849, 2013 | 21 | 2013 |
| β3-chimaerin, a novel member of the chimaerin Rac-GAP family L Zubeldia-Brenner, A Gutierrez-Uzquiza, L Barrio-Real, H Wang, ... Molecular biology reports 41, 2067-2076, 2014 | 18 | 2014 |
| C3G downregulation induces the acquisition of a mesenchymal phenotype that enhances aggressiveness of glioblastoma cells S Manzano, A Gutierrez-Uzquiza, P Bragado, C Sequera, Ó Herranz, ... Cell death & disease 12 (4), 1-17, 2021 | 16 | 2021 |
| C3G is upregulated in hepatocarcinoma, contributing to tumor growth and progression and to HGF/MET pathway activation C Sequera, P Bragado, S Manzano, M Arechederra, S Richelme, ... Cancers 12 (8), 2282, 2020 | 14 | 2020 |
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