Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations CP Fulco, J Nasser, TR Jones, G Munson, DT Bergman, V Subramanian, ... Nature genetics 51 (12), 1664-1669, 2019 | 868 | 2019 |
Inherited causes of clonal haematopoiesis in 97,691 whole genomes AG Bick, JS Weinstock, SK Nandakumar, CP Fulco, EL Bao, SM Zekavat, ... Nature 586 (7831), 763-768, 2020 | 571 | 2020 |
Genome-wide enhancer maps link risk variants to disease genes J Nasser, DT Bergman, CP Fulco, P Guckelberger, BR Doughty, ... Nature 593 (7858), 238-243, 2021 | 508 | 2021 |
Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases EM Weeks, JC Ulirsch, NY Cheng, BL Trippe, RS Fine, J Miao, ... Nature Genetics, 1-10, 2023 | 204 | 2023 |
Compatibility rules of human enhancer and promoter sequences DT Bergman, TR Jones, V Liu, J Ray, E Jagoda, L Siraj, HY Kang, ... Nature 607 (7917), 176-184, 2022 | 117 | 2022 |
Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity S Gazal, O Weissbrod, F Hormozdiari, KK Dey, J Nasser, KA Jagadeesh, ... Nature genetics 54 (6), 827-836, 2022 | 114 | 2022 |
Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk YA Reshef, HK Finucane, DR Kelley, A Gusev, D Kotliar, JC Ulirsch, ... Nature genetics 50 (10), 1483-1493, 2018 | 71 | 2018 |
KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress JR Moonen, J Chappell, M Shi, T Shinohara, D Li, MR Mumbach, F Zhang, ... Nature communications 13 (1), 4941, 2022 | 47 | 2022 |
An encyclopedia of enhancer-gene regulatory interactions in the human genome AR Gschwind, KS Mualim, A Karbalayghareh, MU Sheth, KK Dey, ... bioRxiv, 2023 | 31 | 2023 |
HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes JL Marshall, BR Doughty, V Subramanian, P Guckelberger, Q Wang, ... Proceedings of the National Academy of Sciences 117 (52), 33404-33413, 2020 | 28 | 2020 |
SNP-to-gene linking strategies reveal contributions of enhancer-related and candidate master-regulator genes to autoimmune disease KK Dey, S Gazal, B van de Geijn, SS Kim, J Nasser, JM Engreitz, AL Price Cell genomics 2 (7), 2022 | 26 | 2022 |
Inherited causes of clonal hematopoiesis of indeterminate potential in TOPMed whole genomes AG Bick, JS Weinstock, SK Nandakumar, CP Fulco, MJ Leventhal, EL Bao, ... BioRxiv, 782748, 2019 | 23 | 2019 |
Functional disease architectures reveal unique biological role of transposable elements F Hormozdiari, B van de Geijn, J Nasser, O Weissbrod, S Gazal, CJT Ju, ... Nature communications 10 (1), 4054, 2019 | 15 | 2019 |
Contribution of enhancer-driven and master-regulator genes to autoimmune disease revealed using functionally informed SNP-to-gene linking strategies KK Dey, SK Gazal, B van de Geijn, SS Kim, J Nasser, JM Engreitz, A Price bioRxiv, 2020.09. 02.279059, 2021 | 8 | 2021 |
Cohesin-mediated 3D contacts tune enhancer-promoter regulation P Guckelberger, BR Doughty, G Munson, SSP Rao, Y Tan, XS Cai, ... bioRxiv, 2024.07. 12.603288, 2024 | 5 | 2024 |
Combining SNP-to-gene linking strategies to pinpoint disease genes and assess disease omnigenicity S Gazal, O Weissbrod, F Hormozdiari, K Dey, J Nasser, K Jagadeesh, ... medRxiv, 2021 | 5 | 2021 |
Integrative approaches to improve the informativeness of deep learning models for human complex diseases KK Dey, SS Kim, S Gazal, J Nasser, JM Engreitz, A Price bioRxiv, 2020 | 3 | 2020 |
HyPR Protocol J Marshall, BR Doughty, V Subramanian, P Guckelberger, Q Wang, ... | 1 | 2020 |
A mathematical model clarifies the ABC Score formula used in enhancer-gene prediction J Nasser, KM Nam, J Gunawardena bioRxiv, 2024.11. 29.626072, 2024 | | 2024 |