Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine K Furuyama, Y Kawaguchi, H Akiyama, M Horiguchi, S Kodama, T Kuhara, ... Nature genetics 43 (1), 34-41, 2011 | 980 | 2011 |
Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers S Chera, D Baronnier, L Ghila, V Cigliola, JN Jensen, G Gu, K Furuyama, ... Nature 514 (7523), 503-507, 2014 | 499 | 2014 |
Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells K Furuyama, S Chera, L van Gurp, D Oropeza, L Ghila, N Damond, ... Nature 567 (7746), 43-48, 2019 | 269 | 2019 |
Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas A Fukuda, Y Kawaguchi, K Furuyama, S Kodama, M Horiguchi, T Kuhara, ... The Journal of clinical investigation 116 (6), 1484-1493, 2006 | 174 | 2006 |
Clinical significance of focal adhesion kinase in resectable pancreatic cancer K Furuyama, R Doi, T Mori, E Toyoda, D Ito, K Kami, M Koizumi, A Kida, ... World journal of surgery 30, 219-226, 2006 | 113 | 2006 |
Reduction of Ptf1a Gene Dosage Causes Pancreatic Hypoplasia and Diabetes in Mice A Fukuda, Y Kawaguchi, K Furuyama, S Kodama, M Horiguchi, T Kuhara, ... Diabetes 57 (9), 2421-2431, 2008 | 78 | 2008 |
Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells V Cigliola, L Ghila, F Thorel, L van Gurp, D Baronnier, D Oropeza, ... Nature cell biology 20 (11), 1267-1277, 2018 | 66 | 2018 |
Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production M Perez-Frances, L van Gurp, MV Abate, V Cigliola, K Furuyama, ... Nature Communications 12 (1), 4458, 2021 | 63 | 2021 |
Generation of human islet cell type-specific identity genesets L van Gurp, L Fodoulian, D Oropeza, K Furuyama, E Bru-Tari, AN Vu, ... Nature communications 13 (1), 2020, 2022 | 52 | 2022 |
Rbp‐j regulates expansion of pancreatic epithelial cells and their differentiation into exocrine cells during mouse development J Fujikura, K Hosoda, Y Kawaguchi, M Noguchi, H Iwakura, S Odori, ... Developmental dynamics: an official publication of the American Association …, 2007 | 42 | 2007 |
Loss of the major duodenal papilla results in brown pigment biliary stone formation in pdx1 null mice A Fukuda, Y Kawaguchi, K Furuyama, S Kodama, T Kuhara, M Horiguchi, ... Gastroenterology 130 (3), 855-867, 2006 | 38 | 2006 |
Impact of Sox9 dosage and Hes1-mediated Notch signaling in controlling the plasticity of adult pancreatic duct cells in mice S Hosokawa, K Furuyama, M Horiguchi, Y Aoyama, K Tsuboi, M Sakikubo, ... Scientific reports 5 (1), 8518, 2015 | 36 | 2015 |
CAPS1 deficiency perturbs dense-core vesicle trafficking and Golgi structure and reduces presynaptic release probability in the mouse brain T Sadakata, W Kakegawa, Y Shinoda, M Hosono, R Katoh-Semba, ... Journal of Neuroscience 33 (44), 17326-17334, 2013 | 32 | 2013 |
Nardilysin is required for maintaining pancreatic β-cell function K Nishi, Y Sato, M Ohno, Y Hiraoka, S Saijo, J Sakamoto, PM Chen, ... Diabetes 65 (10), 3015-3027, 2016 | 27 | 2016 |
Ptf1a inactivation in adult pancreatic acinar cells causes apoptosis through activation of the endoplasmic reticulum stress pathway M Sakikubo, K Furuyama, M Horiguchi, S Hosokawa, Y Aoyama, K Tsuboi, ... Scientific reports 8 (1), 15812, 2018 | 25 | 2018 |
Liver‐specific Prox1 inactivation causes hepatic injury and glucose intolerance in mice T Goto, A Elbahrawy, K Furuyama, M Horiguchi, S Hosokawa, Y Aoyama, ... FEBS letters 591 (4), 624-635, 2017 | 21 | 2017 |
Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice S Kodama, Y Nakano, K Hirata, K Furuyama, M Horiguchi, T Kuhara, ... Scientific Reports 6 (1), 21211, 2016 | 20 | 2016 |
Combined inhibition of menin-MLL interaction and TGF-β signaling induces replication of human pancreatic beta cells S Pahlavanneshan, M Behmanesh, D Oropeza, K Furuyama, ... European journal of cell biology 99 (5), 151094, 2020 | 11 | 2020 |
Bioinformatic Analyses of miRNA–mRNA Signature during hiPSC Differentiation towards Insulin-Producing Cells upon HNF4α Mutation L Ghila, Y Bjørlykke, TA Legøy, H Vethe, K Furuyama, S Chera, H Ræder Biomedicines 8 (7), 179, 2020 | 8 | 2020 |
In vitro methods to ensure absence of residual undifferentiated human induced pluripotent stem cells intermingled in induced nephron progenitor cells H Tsujimoto, N Katagiri, Y Ijiri, B Sasaki, Y Kobayashi, A Mima, ... PLoS One 17 (11), e0275600, 2022 | 6 | 2022 |