Control of mitochondrial morphology by a human mitofusin A Santel, MT Fuller Journal of cell science 114 (5), 867-874, 2001 | 1330 | 2001 |
Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis M Karbowski, YJ Lee, B Gaume, SY Jeong, S Frank, A Nechushtan, ... The Journal of cell biology 159 (6), 931-938, 2002 | 1038 | 2002 |
Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells A Santel, S Frank, B Gaume, M Herrler, RJ Youle, MT Fuller Journal of cell science 116 (13), 2763-2774, 2003 | 530 | 2003 |
Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression M Aleku, P Schulz, O Keil, A Santel, U Schaeper, B Dieckhoff, O Janke, ... Cancer research 68 (23), 9788-9798, 2008 | 417 | 2008 |
The mitochondrial protein MTP18 contributes to mitochondrial fission in mammalian cells D Tondera, F Czauderna, K Paulick, R Schwarzer, J Kaufmann, A Santel Journal of cell science 118 (14), 3049-3059, 2005 | 291 | 2005 |
First-in-human phase I study of the liposomal RNA interference therapeutic Atu027 in patients with advanced solid tumors B Schultheis, D Strumberg, A Santel, C Vank, F Gebhardt, O Keil, C Lange, ... Journal of clinical oncology 32 (36), 4141-4148, 2014 | 282 | 2014 |
Inducible shRNA expression for application in a prostate cancer mouse model F Czauderna, A Santel, M Hinz, M Fechtner, B Durieux, G Fisch, ... Nucleic acids research 31 (21), e127-e127, 2003 | 252 | 2003 |
Knockdown of MTP18, a novel phosphatidylinositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosis D Tondera, A Santel, R Schwarzer, S Dames, K Giese, A Klippel, ... Journal of Biological Chemistry 279 (30), 31544-31555, 2004 | 174 | 2004 |
Shaping mitochondria: The complex posttranslational regulation of the mitochondrial fission protein DRP1 A Santel, S Frank IUBMB life 60 (7), 448-455, 2008 | 173 | 2008 |
Phase I clinical development of Atu027, a siRNA formulation targeting PKN3 in patients with advanced solid tumors D Strumberg, B Schultheis, U Traugott, C Vank, A Santel, O Keil, K Giese, ... International Journal of Clinical Pharmacologyand Therapeutics 50 (1), 76, 2012 | 172 | 2012 |
The Drosophila don juan (dj) gene encodes a novel sperm specific protein component characterized by an unusual domain of a repetitive amino acid motif A Santel, T Winhauer, N Blümer, R Renkawitz-Pohl Mechanisms of development 64 (1-2), 19-30, 1997 | 145 | 1997 |
PKN3 is required for malignant prostate cell growth downstream of activated PI 3‐kinase F Leenders, K Möpert, A Schmiedeknecht, A Santel, F Czauderna, ... The EMBO journal 23 (16), 3303-3313, 2004 | 142 | 2004 |
Atu027 prevents pulmonary metastasis in experimental and spontaneous mouse metastasis models A Santel, M Aleku, N Röder, K Möpert, B Durieux, O Janke, O Keil, ... Clinical Cancer Research 16 (22), 5469-5480, 2010 | 127 | 2010 |
Delivery of therapeutic siRNA to the lung endothelium via novel lipoplex formulation DACC V Fehring, U Schaeper, K Ahrens, A Santel, O Keil, M Eisermann, K Giese, ... Molecular Therapy 22 (4), 811-820, 2014 | 114 | 2014 |
Gene control of tyrosine kinase TIE2 and vascular manifestations of infections CC Ghosh, S David, R Zhang, A Berghelli, K Milam, SJ Higgins, J Hunter, ... Proceedings of the National Academy of Sciences 113 (9), 2472-2477, 2016 | 107 | 2016 |
Differential expression of the Drosophila mitofusin genes fuzzy onions (fzo) and dmfn JJ Hwa, MA Hiller, MT Fuller, A Santel Mechanisms of development 116 (1-2), 213-216, 2002 | 94 | 2002 |
Get the balance right: mitofusins roles in health and disease A Santel Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1763 (5-6), 490-499, 2006 | 89 | 2006 |
Prognostic and pathogenic role of angiopoietin-1 and-2 in pneumonia B Gutbier, AK Neuhauß, K Reppe, C Ehrler, A Santel, J Kaufmann, ... American journal of respiratory and critical care medicine 198 (2), 220-231, 2018 | 80 | 2018 |
Lung-targeted RNA interference against angiopoietin-2 ameliorates multiple organ dysfunction and death in sepsis T Stiehl, K Thamm, J Kaufmann, U Schaeper, T Kirsch, H Haller, A Santel, ... Critical care medicine 42 (10), e654-e662, 2014 | 77 | 2014 |
Adrenomedullin attenuates ventilator-induced lung injury in mice HC Müller, M Witzenrath, T Tschernig, B Gutbier, S Hippenstiel, A Santel, ... Thorax 65 (12), 1077-1084, 2010 | 71 | 2010 |