Combinatorial gene therapy accelerates bone regeneration: non-viral dual delivery of VEGF and BMP2 in a collagen-nanohydroxyapatite scaffold. C Curtin, EG Tierney, K McSorley, SA Cryan, G Duffy, F O'Brien Royal College of Surgeons in Ireland, 2015 | 199 | 2015 |
Gene delivery of TGF-β3 and BMP2 in an MSC-laden alginate hydrogel for articular cartilage and endochondral bone tissue engineering T Gonzalez-Fernandez, EG Tierney, GM Cunniffe, FJ O'Brien, DJ Kelly Tissue Engineering Part A 22 (9-10), 776-787, 2016 | 168 | 2016 |
The development of non-viral gene-activated matrices for bone regeneration using polyethyleneimine (PEI) and collagen-based scaffolds EG Tierney, GP Duffy, AJ Hibbitts, SA Cryan, FJ O'Brien Journal of Controlled Release 158 (2), 304-311, 2012 | 135 | 2012 |
The use of collagen-based scaffolds to simulate prostate cancer bone metastases with potential for evaluating delivery of nanoparticulate gene therapeutics KA Fitzgerald, J Guo, EG Tierney, CM Curtin, M Malhotra, R Darcy, ... Biomaterials 66, 53-66, 2015 | 129 | 2015 |
Development of a gene-activated scaffold platform for tissue engineering applications using chitosan-pDNA nanoparticles on collagen-based scaffolds RM Raftery, EG Tierney, CM Curtin, SA Cryan, FJ O'Brien Journal of Controlled Release 210, 84-94, 2015 | 124 | 2015 |
High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a … EG Tierney, K McSorley, CL Hastings, SA Cryan, T O'Brien, MJ Murphy, ... Journal of controlled release 165 (3), 173-182, 2013 | 68 | 2013 |
Non-viral gene-activated matrices: next generation constructs for bone repair EG Tierney, GP Duffy, SA Cryan, CM Curtin, FJ O’Brien Organogenesis 9 (1), 22-28, 2013 | 61 | 2013 |
Novel oligochitosan-mediated gene delivery to mesenchymal stem cells loaded onto collagen scaffolds promotes bone regeneration R Raftery, E Tierney, C Curtin, SA Cryan, F O'brien JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 8, 80-81, 2014 | 1 | 2014 |
Highly Efficient Non-Viral Gene-Activated Matrices Incorporating Angiogenic and Osteogenic Genes Enhances Bone Tissue Regeneration In Vivo EG Tierney, CM Curtin, SA Cryan, GP Duffy, FJ O'Brien IRISH JOURNAL OF MEDICAL SCIENCE 185, S40-S41, 2016 | | 2016 |
Gene-activated Alginate Hydrogels for Articular Cartilage and Endochondral Bone Tissue Engineering T Gonzalez-Fernandez, EG Tierney, FJ O'Brien, DJ Kelly TISSUE ENGINEERING PART A 21, S141-S141, 2015 | | 2015 |
GENE-ACTIVATED SCAFFOLDS INCORPORATING ANGIOGENIC AND OSTEOGENIC GENES ENHANCE BONE TISSUE REGENERATION EG Tierney, CM Curtin, SA Cryan, GP Duffy, FJ O'Brien Orthopaedic Proceedings 96 (SUPP_10), 15-15, 2014 | | 2014 |
Alginate hydrogels as a 3D gene delivery platform for cartilage tissue engineering T Gonzalez-Fernandez, EG Tierney, FJ O'Brien, DJ Kelly JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 8, 91-92, 2014 | | 2014 |
Development of a gene-activated matrix for enhanced bone tissue regeneration combining dual angiogenic and osteogenic non-viral gene delivery EG Tierney, CM Curtin, SA Cryan, GP Duffy, FJ O'Brien JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 6, 290-290, 2012 | | 2012 |
CHARACTERISATION AND OPTIMISATION OF POLYETHYLENEIMINE-PDNA POLYPLEXES FOR DEVELOPMENT OF AN OSTEOINDUCTIVE'SMART'SCAFFOLD EG Tierney, GP Duffy, AJ Hibbitts, SA Cryan, CM Curtin, FJ O'Brien IRISH JOURNAL OF MEDICAL SCIENCE 179, S287-S288, 2010 | | 2010 |