| Resolving medulloblastoma cellular architecture by single-cell genomics V Hovestadt, KS Smith, L Bihannic, MG Filbin, MKL Shaw, A Baumgartner, ... Nature 572 (7767), 74-79, 2019 | 386 | 2019 |
| Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial GW Robinson, VA Rudneva, I Buchhalter, CA Billups, SM Waszak, ... The Lancet Oncology 19 (6), 768-784, 2018 | 223 | 2018 |
| Outcomes by clinical and molecular features in children with medulloblastoma treated with risk-adapted therapy: results of an international phase III trial (SJMB03) A Gajjar, GW Robinson, KS Smith, T Lin, TE Merchant, M Chintagumpala, ... Journal of Clinical Oncology 39 (7), 822-835, 2021 | 180 | 2021 |
| Germline elongator mutations in sonic hedgehog medulloblastoma SM Waszak, GW Robinson, BL Gudenas, KS Smith, A Forget, M Kojic, ... Nature 580 (7803), 396-401, 2020 | 149 | 2020 |
| Children's oncology group phase III trial of reduced-dose and reduced-volume radiotherapy with chemotherapy for newly diagnosed average-risk medulloblastoma JM Michalski, AJ Janss, LG Vezina, KS Smith, CA Billups, PC Burger, ... Journal of Clinical Oncology 39 (24), 2685-2697, 2021 | 128 | 2021 |
| Serial assessment of measurable residual disease in medulloblastoma liquid biopsies APY Liu, KS Smith, R Kumar, L Paul, L Bihannic, T Lin, KK Maass, ... Cancer cell 39 (11), 1519-1530. e4, 2021 | 107 | 2021 |
| scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy JK Ocasio, B Babcock, D Malawsky, SJ Weir, L Loo, JM Simon, MJ Zylka, ... Nature communications 10 (1), 5829, 2019 | 107 | 2019 |
| Efficacy of carboplatin and isotretinoin in children with high-risk medulloblastoma: a randomized clinical trial from the Children’s Oncology Group SES Leary, RJ Packer, Y Li, CA Billups, KS Smith, A Jaju, L Heier, ... JAMA oncology 7 (9), 1313-1321, 2021 | 104 | 2021 |
| Unified rhombic lip origins of group 3 and group 4 medulloblastoma KS Smith, L Bihannic, BL Gudenas, P Haldipur, R Tao, Q Gao, Y Li, ... Nature 609 (7929), 1012-1020, 2022 | 102 | 2022 |
| Clinical outcomes and patient-matched molecular composition of relapsed medulloblastoma R Kumar, KS Smith, M Deng, C Terhune, GW Robinson, BA Orr, APY Liu, ... Journal of Clinical Oncology 39 (7), 807-821, 2021 | 83 | 2021 |
| NRL and CRX define photoreceptor identity and reveal subgroup-specific dependencies in medulloblastoma A Garancher, CY Lin, M Morabito, W Richer, N Rocques, M Larcher, ... Cancer cell 33 (3), 435-449. e6, 2018 | 80 | 2018 |
| Deconstructing sonic hedgehog medulloblastoma: molecular subtypes, drivers, and beyond J Garcia-Lopez, R Kumar, KS Smith, PA Northcott Trends in Genetics 37 (3), 235-250, 2021 | 72 | 2021 |
| DDX3X suppresses the susceptibility of hindbrain lineages to medulloblastoma DM Patmore, A Jassim, E Nathan, RJ Gilbertson, D Tahan, N Hoffmann, ... Developmental cell 54 (4), 455-470. e5, 2020 | 67 | 2020 |
| Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource KS Smith, K Xu, KS Mercer, F Boop, P Klimo, M DeCupyere, J Grenet, ... Acta Neuropathologica 140, 209-225, 2020 | 66 | 2020 |
| SomVarIUS: somatic variant identification from unpaired tissue samples KS Smith, VK Yadav, S Pei, DA Pollyea, CT Jordan, S De Bioinformatics 32 (6), 808-813, 2016 | 62 | 2016 |
| Subgroup and subtype-specific outcomes in adult medulloblastoma H Coltin, L Sundaresan, KS Smith, P Skowron, L Massimi, CG Eberhart, ... Acta neuropathologica 142 (5), 859-871, 2021 | 51 | 2021 |
| Nuclear topology modulates the mutational landscapes of cancer genomes KS Smith, LL Liu, S Ganesan, F Michor, S De Nature structural & molecular biology 24 (11), 1000-1006, 2017 | 40 | 2017 |
| Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination V Martirosian, K Deshpande, H Zhou, K Shen, K Smith, P Northcott, M Lin, ... Cell reports 35 (13), 2021 | 39 | 2021 |
| Signatures of accelerated somatic evolution in gene promoters in multiple cancer types KS Smith, VK Yadav, BS Pedersen, R Shaknovich, MW Geraci, KS Pollard, ... Nucleic acids research 43 (11), 5307-5317, 2015 | 39 | 2015 |
| Vorinostat and isotretinoin with chemotherapy in young children with embryonal brain tumors: a report from the Pediatric Brain Tumor Consortium (PBTC-026) SES Leary, L Kilburn, JR Geyer, M Kocak, J Huang, KS Smith, J Hadley, ... Neuro-oncology 24 (7), 1178-1190, 2022 | 25 | 2022 |
