| Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase T Yamauchi, J Kamon, Y Minokoshi, Y Ito, H Waki, S Uchida, S Yamashita, ... Nature medicine 8 (11), 1288-1295, 2002 | 5790 | 2002 |
| AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism BB Kahn, T Alquier, D Carling, DG Hardie Cell metabolism 1 (1), 15-25, 2005 | 3525 | 2005 |
| Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase Y Minokoshi, YB Kim, OD Peroni, LGD Fryer, C Müller, D Carling, ... Nature 415 (6869), 339-343, 2002 | 2678 | 2002 |
| LKB1 is the upstream kinase in the AMP-activated protein kinase cascade A Woods, SR Johnstone, K Dickerson, FC Leiper, LGD Fryer, D Neumann, ... Current biology 13 (22), 2004-2008, 2003 | 2026 | 2003 |
| The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? DG Hardie, D Carling, M Carlson Annual review of biochemistry 67 (1), 821-855, 1998 | 1868 | 1998 |
| The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism G Frost, ML Sleeth, M Sahuri-Arisoylu, B Lizarbe, S Cerdan, L Brody, ... Nature communications 5 (1), 3611, 2014 | 1751 | 2014 |
| The AMP‐activated protein kinase: fuel gauge of the mammalian cell? DG Hardie, D Carling European journal of biochemistry 246 (2), 259-273, 1997 | 1740 | 1997 |
| Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells A Woods, K Dickerson, R Heath, SP Hong, M Momcilovic, SR Johnstone, ... Cell metabolism 2 (1), 21-33, 2005 | 1683 | 2005 |
| Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated … SA Hawley, M Davison, A Woods, SP Davies, RK Beri, D Carling, ... Journal of Biological Chemistry 271 (44), 27879-27887, 1996 | 1548 | 1996 |
| The AMP-activated protein kinase cascade–a unifying system for energy control D Carling Trends in biochemical sciences 29 (1), 18-24, 2004 | 1429 | 2004 |
| The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways LGD Fryer, A Parbu-Patel, D Carling Journal of Biological Chemistry 277 (28), 25226-25232, 2002 | 1316 | 2002 |
| Ribosomal protein S6 kinase 1 signaling regulates mammalian life span C Selman, JMA Tullet, D Wieser, E Irvine, SJ Lingard, AI Choudhury, ... Science 326 (5949), 140-144, 2009 | 1290 | 2009 |
| Structure of mammalian AMPK and its regulation by ADP B Xiao, MJ Sanders, E Underwood, R Heath, FV Mayer, D Carmena, ... Nature 472 (7342), 230-233, 2011 | 1138 | 2011 |
| Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia AS Marsin, L Bertrand, MH Rider, J Deprez, C Beauloye, MF Vincent, ... Current biology 10 (20), 1247-1255, 2000 | 1053 | 2000 |
| Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism TAJ Haystead, ATR Sim, D Carling, RC Honnor, Y Tsukitani, P Cohen, ... Nature 337 (6202), 78-81, 1989 | 1006 | 1989 |
| AMPK, insulin resistance, and the metabolic syndrome NB Ruderman, D Carling, M Prentki, JM Cacicedo The Journal of clinical investigation 123 (7), 2764-2772, 2013 | 995 | 2013 |
| AMP-activated protein kinase plays a role in the control of food intake U Andersson, K Filipsson, CR Abbott, A Woods, K Smith, SR Bloom, ... Journal of Biological Chemistry 279 (13), 12005-12008, 2004 | 985 | 2004 |
| Adenosine 5′-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype D Sag, D Carling, RD Stout, J Suttles The Journal of Immunology 181 (12), 8633-8641, 2008 | 868 | 2008 |
| Characterization of AMP-activated protein kinase γ-subunit isoforms and their role in AMP binding PCF CHEUNG, IP SALT, SP DAVIES, DG HARDIE, D CARLING Biochemical Journal 346 (3), 659-669, 2000 | 850 | 2000 |
| Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade MJ Sanders, PO Grondin, BD Hegarty, MA Snowden, D Carling Biochemical Journal 403 (1), 139-148, 2007 | 796 | 2007 |
