Structure–Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae CS Hewitt, NS Abutaleb, AEM Elhassanny, A Nocentini, X Cao, DP Amos, ... ACS infectious diseases 7 (7), 1969-1984, 2021 | 71 | 2021 |
Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae NS Abutaleb, AEM Elhassanny, A Nocentini, CS Hewitt, A Elkashif, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 51-61, 2022 | 44 | 2022 |
Coumarins effectively inhibit bacterial α-carbonic anhydrases S Giovannuzzi, CS Hewitt, A Nocentini, C Capasso, DP Flaherty, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 333-338, 2022 | 40 | 2022 |
Ubiquitin C‐Terminal Hydrolase L1: Biochemical and Cellular Characterization of a Covalent Cyanopyrrolidine‐Based Inhibitor AD Krabill, H Chen, S Hussain, C Feng, A Abdullah, C Das, UK Aryal, ... ChemBioChem 21 (5), 712-722, 2020 | 40 | 2020 |
Structure-activity relationship studies for inhibitors for vancomycin-resistant Enterococcus and human carbonic anhydrases W An, KJ Holly, A Nocentini, RD Imhoff, CS Hewitt, NS Abutaleb, X Cao, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1838-1844, 2022 | 31 | 2022 |
Inhibition studies of bacterial α-carbonic anhydrases with phenols S Giovannuzzi, CS Hewitt, A Nocentini, C Capasso, G Costantino, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 666-671, 2022 | 28 | 2022 |
Anion inhibition studies of the α-carbonic anhydrases from Neisseria gonorrhoeae A Nocentini, CS Hewitt, MD Mastrolorenzo, DP Flaherty, CT Supuran Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1061-1066, 2021 | 27 | 2021 |
Dithiocarbamates effectively inhibit the α-carbonic anhydrase from Neisseria gonorrhoeae S Giovannuzzi, NS Abutaleb, CS Hewitt, F Carta, A Nocentini, MN Seleem, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1-8, 2022 | 25 | 2022 |
Development of ubiquitin variants with selectivity for ubiquitin C-terminal hydrolase deubiquitinases CS Hewitt, AD Krabill, C Das, DP Flaherty Biochemistry 59 (37), 3447-3462, 2020 | 15 | 2020 |
Rational Development and Characterization of a Ubiquitin Variant with Selectivity for Ubiquitin C-Terminal Hydrolase L3 CS Hewitt, C Das, DP Flaherty Biomolecules 12 (1), 62, 2022 | 8 | 2022 |
Optimization and Anti-Cancer Properties of Fluoromethylketones as covalent inhibitors for Ubiquitin C-terminal Hydrolase L1 AD Krabill, H Chen, S Hussain, CS Hewitt, RD Imhoff, CS Muli, C Das, ... Molecules 26 (5), 1227, 2021 | 8 | 2021 |
Insights into ubiquitin product release in hydrolysis catalyzed by the bacterial deubiquitinase SdeA MJ Sheedlo, S Kenny, IS Podkorytov, K Brown, J Ma, S Iyer, CS Hewitt, ... Biochemistry 60 (8), 584-596, 2021 | 6 | 2021 |
Altered Protein Dynamics and a More Reactive Catalytic Cysteine in a Neurodegeneration-associated UCHL1 Mutant S Kenny, CH Lai, TS Chiang, K Brown, CS Hewitt, AD Krabill, HT Chang, ... Journal of Molecular Biology 436 (4), 168438, 2024 | 2 | 2024 |
Development of Ubiquitin Variants with Selectivity for the Ubiquitin C-Terminal Hydrolase Subfamily of Deubiquitinases CS Hewitt Purdue University, 2021 | | 2021 |