G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy E Ruggiero, SN Richter Nucleic acids research 46 (7), 3270-3283, 2018 | 420 | 2018 |
Viral G-quadruplexes: New frontiers in virus pathogenesis and antiviral therapy E Ruggiero, SN Richter Annual reports in medicinal chemistry 54, 101-131, 2020 | 102 | 2020 |
The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes M Scalabrin, I Frasson, E Ruggiero, R Perrone, E Tosoni, S Lago, ... Scientific reports 7 (1), 45244, 2017 | 79 | 2017 |
G-quadruplex targeting in the fight against viruses: An update E Ruggiero, I Zanin, M Terreri, SN Richter International journal of molecular sciences 22 (20), 10984, 2021 | 71 | 2021 |
7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full … PG Baraldi, G Saponaro, AR Moorman, R Romagnoli, D Preti, S Baraldi, ... Journal of Medicinal Chemistry 55 (14), 6608-6623, 2012 | 62 | 2012 |
Discovery of 1, 5-diphenylpyrazole-3-carboxamide derivatives as potent, reversible, and selective monoacylglycerol lipase (MAGL) inhibitors M Aghazadeh Tabrizi, PG Baraldi, S Baraldi, E Ruggiero, L De Stefano, ... Journal of medicinal chemistry 61 (3), 1340-1354, 2018 | 52 | 2018 |
Synthesis and structure activity relationship investigation of triazolo [1, 5-a] pyrimidines as CB2 cannabinoid receptor inverse agonists MA Tabrizi, PG Baraldi, E Ruggiero, G Saponaro, S Baraldi, G Poli, ... European journal of medicinal chemistry 113, 11-27, 2016 | 45 | 2016 |
A dynamic i-motif with a duplex stem-loop in the long terminal repeat promoter of the HIV-1 proviral genome modulates viral transcription E Ruggiero, S Lago, P Šket, M Nadai, I Frasson, J Plavec, SN Richter Nucleic Acids Research 47 (21), 11057-11068, 2019 | 42 | 2019 |
Genome-wide mapping of i-motifs reveals their association with transcription regulation in live human cells I Zanin, E Ruggiero, G Nicoletto, S Lago, I Maurizio, I Gallina, SN Richter Nucleic Acids Research 51 (16), 8309-8321, 2023 | 41 | 2023 |
Antiviral activity of the G-quadruplex ligand TMPyP4 against herpes simplex virus-1 S Artusi, E Ruggiero, M Nadai, B Tosoni, R Perrone, A Ferino, I Zanin, ... Viruses 13 (2), 196, 2021 | 41 | 2021 |
The MDM2 inducible promoter folds into four-tetrad antiparallel G-quadruplexes targetable to fight malignant liposarcoma S Lago, M Nadai, E Ruggiero, M Tassinari, M Marušič, B Tosoni, I Frasson, ... Nucleic acids research 49 (2), 847-863, 2021 | 31 | 2021 |
Stable and conserved G-quadruplexes in the long terminal repeat promoter of retroviruses E Ruggiero, M Tassinari, R Perrone, M Nadai, SN Richter ACS infectious diseases 5 (7), 1150-1159, 2019 | 30 | 2019 |
Discovery of 7-Oxopyrazolo[1,5-a]pyrimidine-6-carboxamides as Potent and Selective CB2 Cannabinoid Receptor Inverse Agonists M Aghazadeh Tabrizi, PG Baraldi, G Saponaro, AR Moorman, ... Journal of Medicinal Chemistry 56 (11), 4482-4496, 2013 | 30 | 2013 |
Targeting G-quadruplexes to achieve antiviral activity E Ruggiero, SN Richter Bioorganic & medicinal chemistry letters 79, 129085, 2023 | 29 | 2023 |
Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH) MA Tabrizi, PG Baraldi, E Ruggiero, G Saponaro, S Baraldi, R Romagnoli, ... European Journal of Medicinal Chemistry 97, 289-305, 2015 | 26 | 2015 |
Human genomic DNA is widely interspersed with i-motif structures CD Peña Martinez, M Zeraati, R Rouet, O Mazigi, JY Henry, B Gloss, ... The EMBO journal 43 (20), 4786-4804, 2024 | 21 | 2024 |
Fused in liposarcoma protein, a new player in the regulation of HIV-1 transcription, binds to known and newly identified LTR G-quadruplexes E Ruggiero, I Frasson, E Tosoni, M Scalabrin, R Perrone, M Marušič, ... ACS infectious diseases 8 (5), 958-968, 2022 | 14 | 2022 |
One-Pot Reaction To Obtain N,N′-Disubstituted Guanidines of Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine Scaffold as Human A3 Adenosine Receptor … PG Baraldi, S Baraldi, G Saponaro, M Aghazadeh Tabrizi, R Romagnoli, ... Journal of Medicinal Chemistry 58 (13), 5355-5360, 2015 | 10 | 2015 |
G-quadruplexes in an SVA retrotransposon cause aberrant TAF1 gene expression in X-linked dystonia parkinsonism G Nicoletto, M Terreri, I Maurizio, E Ruggiero, FM Cernilogar, CA Vaine, ... Nucleic Acids Research 52 (19), 11571-11586, 2024 | 4 | 2024 |
New Synthesis of Diazepino[3,2,1‐ij]quinoline and Pyrido[1,2,3‐de]quinoxalines via Addition–Elimination Followed by Cycloacylation PG Baraldi, E Ruggiero, MA Tabrizi Journal of Heterocyclic Chemistry 51 (1), 101-105, 2014 | 4 | 2014 |