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Michael Scofield
Michael Scofield
Bestätigte E-Mail-Adresse bei musc.edu - Startseite
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The nucleus accumbens: mechanisms of addiction across drug classes reflect the importance of glutamate homeostasis
MD Scofield, JA Heinsbroek, CD Gipson, YM Kupchik, S Spencer, ...
Pharmacological reviews 68 (3), 816-871, 2016
5962016
Gq-DREADD Selectively Initiates Glial Glutamate Release and Inhibits Cue-induced Cocaine Seeking
MD Scofield, HA Boger, RJ Smith, H Li, PG Haydon, PW Kalivas
Biological Psychiatry, 2015
2272015
Astrocytic dysfunction and addiction: consequences of impaired glutamate homeostasis
MD Scofield, PW Kalivas
The Neuroscientist 20 (6), 610-622, 2014
2212014
Glutamate transporter GLT‐1 mediates N‐acetylcysteine inhibition of cocaine reinstatement
KJ Reissner, CD Gipson, PK Tran, LA Knackstedt, MD Scofield, ...
Addiction biology 20 (2), 316-323, 2015
2052015
Synaptic glutamate spillover due to impaired glutamate uptake mediates heroin relapse
H Shen, MD Scofield, H Boger, M Hensley, PW Kalivas
Journal of Neuroscience 34 (16), 5649-5657, 2014
1852014
Cocaine self-administration and extinction leads to reduced glial fibrillary acidic protein expression and morphometric features of astrocytes in the nucleus accumbens core
MD Scofield, H Li, BM Siemsen, KL Healey, PK Tran, N Woronoff, ...
Biological psychiatry 80 (3), 207-215, 2016
1742016
Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases
ACW Smith, YM Kupchik, MD Scofield, CD Gipson, A Wiggins, ...
Nature neuroscience 17 (12), 1655-1657, 2014
1502014
The nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster: dual role in nicotine addiction and lung cancer
MRD Improgo, MD Scofield, AR Tapper, PD Gardner
Progress in neurobiology 92 (2), 212-226, 2010
1172010
Chemogenetic manipulations of ventral tegmental area dopamine neurons reveal multifaceted roles in cocaine abuse
SV Mahler, ZD Brodnik, BM Cox, WC Buchta, BS Bentzley, J Quintanilla, ...
Journal of Neuroscience 39 (3), 503-518, 2019
1132019
Accumbens nNOS interneurons regulate cocaine relapse
ACW Smith, MD Scofield, JA Heinsbroek, CD Gipson, D Neuhofer, ...
Journal of Neuroscience 37 (4), 742-756, 2017
1062017
The tetrapartite synapse: extracellular matrix remodeling contributes to corticoaccumbens plasticity underlying drug addiction
ACW Smith, MD Scofield, PW Kalivas
Brain research 1628, 29-39, 2015
872015
Heroin cue–evoked astrocytic structural plasticity at nucleus accumbens synapses inhibits heroin seeking
A Kruyer, MD Scofield, D Wood, KJ Reissner, PW Kalivas
Biological psychiatry 86 (11), 811-819, 2019
842019
From smoking to lung cancer: the CHRNA5/A3/B4 connection
MRD Improgo, MD Scofield, AR Tapper, PD Gardner
Oncogene 29 (35), 4874-4884, 2010
832010
Effects of methamphetamine self-administration and extinction on astrocyte structure and function in the nucleus accumbens core
BM Siemsen, CM Reichel, KC Leong, C Garcia-Keller, CD Gipson, ...
Neuroscience 406, 528-541, 2019
822019
A model of Δ9-tetrahydrocannabinol self-administration and reinstatement that alters synaptic plasticity in nucleus accumbens
S Spencer, D Neuhofer, VC Chioma, C Garcia-Keller, DJ Schwartz, ...
Biological psychiatry 84 (8), 601-610, 2018
812018
Cocaine and sucrose rewards recruit different seeking ensembles in the nucleus accumbens core
AC Bobadilla, E Dereschewitz, L Vaccaro, JA Heinsbroek, MD Scofield, ...
Molecular psychiatry 25 (12), 3150-3163, 2020
742020
MEF2C hypofunction in neuronal and neuroimmune populations produces MEF2C haploinsufficiency syndrome–like behaviors in mice
AJ Harrington, CM Bridges, S Berto, K Blankenship, JY Cho, A Assali, ...
Biological psychiatry 88 (6), 488-499, 2020
512020
Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum
YM Kupchik, MD Scofield, KC Rice, K Cheng, BP Roques, PW Kalivas
Journal of Neuroscience 34 (3), 1057-1066, 2014
512014
Exploring the role of astroglial glutamate release and association with synapses in neuronal function and behavior
MD Scofield
Biological Psychiatry 84 (11), 778-786, 2018
502018
Astrocyte regulation of synaptic signaling in psychiatric disorders
A Kruyer, PW Kalivas, MD Scofield
Neuropsychopharmacology 48 (1), 21-36, 2023
472023
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