| Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia A Giustacchini, S Thongjuea, N Barkas, PS Woll, BJ Povinelli, CAG Booth, ... Nature medicine 23 (6), 692-702, 2017 | 431 | 2017 |
| Unravelling intratumoral heterogeneity through high-sensitivity single-cell mutational analysis and parallel RNA sequencing A Rodriguez-Meira, G Buck, SA Clark, BJ Povinelli, V Alcolea, E Louka, ... Molecular cell 73 (6), 1292-1305. e8, 2019 | 301 | 2019 |
| Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion VTM Nguyen, I Barozzi, M Faronato, Y Lombardo, JH Steel, N Patel, ... Nature communications 6 (1), 10044, 2015 | 147 | 2015 |
| Single-cell analyses reveal megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets B Psaila, G Wang, A Rodriguez-Meira, R Li, EF Heuston, L Murphy, D Yee, ... Molecular cell 78 (3), 477-492. e8, 2020 | 142 | 2020 |
| Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development A Roy, G Wang, D Iskander, S O’Byrne, N Elliott, J O’Sullivan, G Buck, ... Cell Reports 36 (11), 109698, 2021 | 60 | 2021 |
| SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer Y Perone, AJ Farrugia, A Rodríguez-Meira, B Győrffy, C Ion, A Uggetti, ... Nature communications 10 (1), 2115, 2019 | 60 | 2019 |
| Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution A Rodriguez-Meira, R Norfo, S Wen, AL Chédeville, H Rahman, ... Nature genetics 55 (9), 1531-1541, 2023 | 58 | 2023 |
| Single cell analysis of normal and leukemic hematopoiesis BJ Povinelli, A Rodriguez-Meira, AJ Mead Molecular aspects of medicine 59, 85-94, 2018 | 58 | 2018 |
| TARGET-Seq: A Protocol for High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing A Rodriguez-Meira, J O’Sullivan, H Rahman, AJ Mead STAR Protocols, 100125, 2020 | 39 | 2020 |
| Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia E Louka, B Povinelli, A Rodriguez-Meira, G Buck, WX Wen, G Wang, ... Journal of Experimental Medicine 218 (2), 2019 | 32 | 2019 |
| Tumoral stem cell reprogramming as a driver of cancer: Theory, biological models, implications in cancer therapy C Vicente-Dueñas, J Hauer, L Ruiz-Roca, D Ingenhag, ... Seminars in cancer biology 32, 3-9, 2015 | 32 | 2015 |
| C/EBPα and GATA-2 mutations induce bilineage acute erythroid leukemia through transformation of a neomorphic neutrophil-erythroid progenitor C Di Genua, S Valletta, M Buono, B Stoilova, C Sweeney, ... Cancer cell 37 (5), 690-704. e8, 2020 | 27 | 2020 |
| Deciphering TP53 mutant Cancer Evolution with Single-Cell Multi-Omics A Rodriguez-Meira, R Norfo, WX Wen, AL Chédeville, H Rahman, ... BiorXiv, 2022.03. 28.485984, 2022 | 14 | 2022 |
| Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation C Di Genua, R Norfo, A Rodriguez-Meira, WX Wen, R Drissen, ... haematologica 104 (11), 2215, 2019 | 14 | 2019 |
| Effects of Tamoxifen on the Mutant Allele Burden and Disease Course in Patients with Myeloproliferative Neoplasms-Results of the Tamarin Study C Harrison, J Baxter, RH Boucher, T McKerrell, A Jackson, RS Fletcher, ... BLOOD 136, 2020 | 13* | 2020 |
| Single-Cell Multi-Omics Reveals the Genetic, Cellular and Molecular Landscape of TP53 Mutated Leukemic Transformation in MPN A Rodriguez-Meira, H Rahman, R Norfo, W Wen, A Chédeville, ... Blood 138 (Supplement 1), 3-3, 2021 | 11 | 2021 |
| Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy AS Schnegg-Kaufmann, JAI Thoms, GS Bhuyan, HR Hampton, ... Blood 141 (11), 1316-1321, 2023 | 10 | 2023 |
| Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner TC Luis, N Barkas, J Carrelha, A Giustacchini, S Mazzi, R Norfo, B Wu, ... Nature Communications 14 (1), 6062, 2023 | 9 | 2023 |
| Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors WH Neo, Y Meng, A Rodriguez-Meira, MZH Fadlullah, CAG Booth, ... Nature Communications 12 (1), 7019, 2021 | 9 | 2021 |
| Chromothripsis Orchestrates Leukemic Transformation in Blast Phase MPN through Targetable Amplification of DYRK1A CK Brierley, BH Yip, G Orlando, H Goyal, S Wen, J Wen, MF Levine, ... Blood 142, 993, 2023 | 4 | 2023 |
Adam MeadUniversity of OxfordBestätigte E-Mail-Adresse bei imm.ox.ac.uk
