Opportunities and challenges for transcriptome-wide association studies M Wainberg, N Sinnott-Armstrong, N Mancuso, AN Barbeira, DA Knowles, ... Nature genetics 51 (4), 592-599, 2019 | 817 | 2019 |
Genetics of 35 blood and urine biomarkers in the UK Biobank N Sinnott-Armstrong, Y Tanigawa, D Amar, N Mars, C Benner, M Aguirre, ... Nature genetics 53 (2), 185-194, 2021 | 632 | 2021 |
Deep learning in biomedicine M Wainberg, D Merico, A Delong, BJ Frey Nature biotechnology 36 (9), 829-838, 2018 | 617 | 2018 |
Discovery of common and rare genetic risk variants for colorectal cancer JR Huyghe, SA Bien, TA Harrison, HM Kang, S Chen, SL Schmit, ... Nature genetics 51 (1), 76-87, 2019 | 499 | 2019 |
Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens DW Morgens, M Wainberg, EA Boyle, O Ursu, CL Araya, CK Tsui, ... Nature communications 8 (1), 1-8, 2017 | 386 | 2017 |
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities K Han, SE Pierce, A Li, K Spees, GR Anderson, JA Seoane, YH Lo, ... Nature 580 (7801), 136-141, 2020 | 269 | 2020 |
Are random forests truly the best classifiers? M Wainberg, B Alipanahi, BJ Frey Journal of Machine Learning Research 17 (110), 1-5, 2016 | 208 | 2016 |
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes M Wainberg, RA Kamber, A Balsubramani, RM Meyers, ... Nature genetics 53 (5), 638-649, 2021 | 149 | 2021 |
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements J Tycko, M Wainberg, GK Marinov, O Ursu, GT Hess, BK Ego, Aradhana, ... Nature communications 10 (1), 4063, 2019 | 128 | 2019 |
Cannabis, schizophrenia genetic risk, and psychotic experiences: a cross-sectional study of 109,308 participants from the UK Biobank M Wainberg, GR Jacobs, M di Forti, SJ Tripathy Translational Psychiatry 11 (1), 211, 2021 | 65 | 2021 |
Association of accelerometer-derived sleep measures with lifetime psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank M Wainberg, SE Jones, LM Beaupre, SL Hill, D Felsky, MA Rivas, ... PLoS Medicine 18 (10), e1003782, 2021 | 57 | 2021 |
Predicting gene expression in massively parallel reporter assays: A comparative study A Kreimer, H Zeng, MD Edwards, Y Guo, K Tian, S Shin, R Welch, ... Human mutation 38 (9), 1240-1250, 2017 | 55 | 2017 |
The viral hypothesis: how herpesviruses may contribute to Alzheimer’s disease M Wainberg, T Luquez, DM Koelle, B Readhead, C Johnston, M Darvas, ... Molecular psychiatry 26 (10), 5476-5480, 2021 | 44 | 2021 |
Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: a Mendelian randomization study M Wainberg, A Mahajan, A Kundaje, MI McCarthy, E Ingelsson, ... PLoS medicine 16 (12), e1002982, 2019 | 44 | 2019 |
Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma Y Tanigawa, M Wainberg, J Karjalainen, T Kiiskinen, G Venkataraman, ... PLoS Genetics 16 (5), e1008682, 2020 | 42 | 2020 |
Shared genetic risk loci between Alzheimer’s disease and related dementias, Parkinson’s disease, and amyotrophic lateral sclerosis M Wainberg, SJ Andrews, SJ Tripathy Alzheimer's Research & Therapy 15 (1), 113, 2023 | 38 | 2023 |
High-throughput characterization of Cascade type IE CRISPR guide efficacy reveals unexpected PAM diversity and target sequence preferences B Xu Hua Fu, M Wainberg, A Kundaje, AZ Fire Genetics 206 (4), 1727-1738, 2017 | 38 | 2017 |
To transformers and beyond: large language models for the genome ME Consens, C Dufault, M Wainberg, D Forster, M Karimzadeh, ... arXiv preprint arXiv:2311.07621, 2023 | 37 | 2023 |
Neurobiological, familial and genetic risk factors for dimensional psychopathology in the Adolescent Brain Cognitive Development study M Wainberg, GR Jacobs, AN Voineskos, SJ Tripathy Molecular Psychiatry 27 (6), 2731-2741, 2022 | 34 | 2022 |
Multiomic blood correlates of genetic risk identify presymptomatic disease alterations M Wainberg, AT Magis, JC Earls, JC Lovejoy, N Sinnott-Armstrong, ... Proceedings of the National Academy of Sciences 117 (35), 21813-21820, 2020 | 33 | 2020 |