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Nicolas Lux Fawzi
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Protein phase separation: a new phase in cell biology
S Boeynaems, S Alberti, NL Fawzi, T Mittag, M Polymenidou, F Rousseau, ...
Trends in cell biology 28 (6), 420-435, 2018
18912018
Residue-by-residue view of in vitro FUS granules that bind the C-terminal domain of RNA polymerase II
KA Burke, AM Janke, CL Rhine, NL Fawzi
Molecular cell 60 (2), 231-241, 2015
8982015
ALS mutations disrupt phase separation mediated by α-helical structure in the TDP-43 low-complexity C-terminal domain
AE Conicella, GH Zerze, J Mittal, NL Fawzi
Structure 24 (9), 1537-1549, 2016
8132016
Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity
Z Monahan, VH Ryan, AM Janke, KA Burke, SN Rhoads, GH Zerze, ...
The EMBO journal 36 (20), 2951-2967, 2017
6492017
Molecular interactions underlying liquid− liquid phase separation of the FUS low-complexity domain
AC Murthy, GL Dignon, Y Kan, GH Zerze, SH Parekh, J Mittal, NL Fawzi
Nature structural & molecular biology 26 (7), 637-648, 2019
5952019
Phase separation of C9orf72 dipeptide repeats perturbs stress granule dynamics
S Boeynaems, E Bogaert, D Kovacs, A Konijnenberg, E Timmerman, ...
Molecular cell 65 (6), 1044-1055. e5, 2017
5422017
Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR
NL Fawzi, J Ying, R Ghirlando, DA Torchia, GM Clore
Nature 480 (7376), 268-272, 2011
4432011
A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing
A Wang, AE Conicella, HB Schmidt, EW Martin, SN Rhoads, AN Reeb, ...
The EMBO journal 37 (5), e97452, 2018
4002018
Mechanistic view of hnRNPA2 low-complexity domain structure, interactions, and phase separation altered by mutation and arginine methylation
VH Ryan, GL Dignon, GH Zerze, CV Chabata, R Silva, AE Conicella, ...
Molecular cell 69 (3), 465-479. e7, 2018
3902018
TDP-43 α-helical structure tunes liquid–liquid phase separation and function
AE Conicella, GL Dignon, GH Zerze, HB Schmidt, AM D’Ordine, YC Kim, ...
Proceedings of the National Academy of Sciences 117 (11), 5883-5894, 2020
3242020
Nuclear import receptor inhibits phase separation of FUS through binding to multiple sites
T Yoshizawa, R Ali, J Jiou, HYJ Fung, KA Burke, SJ Kim, Y Lin, ...
Cell 173 (3), 693-705. e22, 2018
3192018
SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs
TM Perdikari, AC Murthy, VH Ryan, S Watters, MT Naik, NL Fawzi
The EMBO journal 39 (24), e106478, 2020
311*2020
Kinetics of amyloid β monomer-to-oligomer exchange by NMR relaxation
NL Fawzi, J Ying, DA Torchia, GM Clore
Journal of the American Chemical Society 132 (29), 9948-9951, 2010
2132010
Structure and Dynamics of the Aβ21–30 Peptide from the Interplay of NMR Experiments and Molecular Simulations
N L. Fawzi, AH Phillips, JZ Ruscio, M Doucleff, DE Wemmer, ...
Journal of the American Chemical Society 130 (19), 6145-6158, 2008
1872008
Membrane bending by protein phase separation
F Yuan, H Alimohamadi, B Bakka, AN Trementozzi, KJ Day, NL Fawzi, ...
Proceedings of the National Academy of Sciences 118 (11), e2017435118, 2021
1832021
TDP-43 condensation properties specify its RNA-binding and regulatory repertoire
M Hallegger, AM Chakrabarti, FCY Lee, BL Lee, AG Amalietti, HM Odeh, ...
Cell 184 (18), 4680-4696. e22, 2021
1762021
Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis
P Fratta, P Sivakumar, J Humphrey, K Lo, T Ricketts, H Oliveira, ...
The EMBO journal 37 (11), e98684, 2018
1722018
Homogeneous and heterogeneous tertiary structure ensembles of amyloid-β peptides
KA Ball, AH Phillips, PS Nerenberg, NL Fawzi, DE Wemmer, ...
Biochemistry 50 (35), 7612-7628, 2011
1632011
Molecular details of protein condensates probed by microsecond long atomistic simulations
W Zheng, GL Dignon, N Jovic, X Xu, RM Regy, NL Fawzi, YC Kim, ...
The Journal of Physical Chemistry B 124 (51), 11671-11679, 2020
1592020
Coarse-grained sequences for protein folding and design
S Brown, NJ Fawzi, T Head-Gordon
Proceedings of the National Academy of Sciences 100 (19), 10712-10717, 2003
1532003
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