| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13793* | 2021 |
| Presenilin-dependent transcriptional control of the Aβ-degrading enzyme neprilysin by intracellular domains of βAPP and APLP R Pardossi-Piquard, A Petit, T Kawarai, C Sunyach, CA Da Costa, ... Neuron 46 (4), 541-554, 2005 | 433 | 2005 |
| Wild-type but not Parkinson's disease-related ala-53→ Thr mutant α-synuclein protects neuronal cells from apoptotic stimuli CA da Costa, K Ancolio, F Checler Journal of Biological Chemistry 275 (31), 24065-24069, 2000 | 281 | 2000 |
| New protease inhibitors prevent γ-secretase-mediated production of Aβ40/42 without affecting Notch cleavage A Petit, F Bihel, CA da Costa, O Pourquié, F Checler, JL Kraus Nature cell biology 3 (5), 507-511, 2001 | 250 | 2001 |
| Presenilin-dependent γ-secretase-mediated control of p53-associated cell death in Alzheimer's disease CA da Costa, C Sunyach, R Pardossi-Piquard, J Sévalle, B Vincent, ... Journal of Neuroscience 26 (23), 6377-6385, 2006 | 228 | 2006 |
| Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease CA Da Costa, C Sunyach, E Giaime, A West, O Corti, A Brice, S Safe, ... Nature cell biology 11 (11), 1370-1375, 2009 | 225 | 2009 |
| α-synuclein lowers p53-dependent apoptotic response of neuronal cells: abolishment by 6-hydroxydopamine and implication for Parkinson′ s disease CA Da Costa, E Paitel, B Vincent, F Checler Journal of Biological Chemistry 277 (52), 50980-50984, 2002 | 195 | 2002 |
| Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons C Alves da Costa, E Paitel, MP Mattson, R Amson, A Telerman, K Ancolio, ... Proceedings of the National Academy of Sciences 99 (6), 4043-4048, 2002 | 159 | 2002 |
| Challenges in glioblastoma research: focus on the tumor microenvironment A Bikfalvi, CA da Costa, T Avril, JV Barnier, L Bauchet, L Brisson, ... Trends in cancer 9 (1), 9-27, 2023 | 155 | 2023 |
| α-Synuclein and the Parkinson's disease-related mutant Ala53Thr-α-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells K Ancolio, CA Da Costa, K Ueda, F Checler Neuroscience letters 285 (2), 79-82, 2000 | 136 | 2000 |
| Role of the proteasome in Alzheimer’s disease F Checler, CA Da Costa, K Ancolio, N Chevallier, E Lopez-Perez, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1502 (1), 133-138, 2000 | 132 | 2000 |
| Endogenous β-amyloid production in presenilin-deficient embryonic mouse fibroblasts M Armogida, A Petit, B Vincent, S Scarzello, CA da Costa, F Checler Nature cell biology 3 (11), 1030-1033, 2001 | 116 | 2001 |
| p53 in neurodegenerative diseases and brain cancers F Checler, CA da Costa Pharmacology & therapeutics 142 (1), 99-113, 2014 | 113 | 2014 |
| Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation T Goiran, E Duplan, L Rouland, W El Manaa, I Lauritzen, J Dunys, H You, ... Cell Death & Differentiation, 1-12, 2018 | 102 | 2018 |
| The C-terminal products of cellular prion protein processing, C1 and C2, exert distinct influence on p53-dependent staurosporine-induced caspase-3 activation C Sunyach, MA Cisse, CA da Costa, B Vincent, F Checler Journal of Biological Chemistry 282 (3), 1956-1963, 2007 | 102 | 2007 |
| Apoptosis in Parkinson's disease: is p53 the missing link between genetic and sporadic Parkinsonism? CA Da Costa, F Checler Cellular signalling 23 (6), 963-968, 2011 | 98 | 2011 |
| ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1 E Duplan, E Giaime, J Viotti, J Sévalle, O Corti, A Brice, H Ariga, L Qi, ... Journal of cell science 126 (9), 2124-2133, 2013 | 95 | 2013 |
| β-Synuclein Displays an Antiapoptotic p53-dependent Phenotype and Protects Neurons from 6-Hydroxydopamine-induced Caspase 3 Activation: CROSS-TALK WITH α-SYNUCLEIN AND … CA da Costa, E Masliah, F Checler Journal of Biological Chemistry 278 (39), 37330-37335, 2003 | 93 | 2003 |
| Overexpression of PrPc triggers caspase 3 activation: potentiation by proteasome inhibitors and blockade by anti‐PrP antibodies E Paitel, C Alves da Costa, D Vilette, J Grassi, F Checler Journal of neurochemistry 83 (5), 1208-1214, 2002 | 90 | 2002 |
| Primary cultured neurons devoid of cellular prion display lower responsiveness to staurosporine through the control of p53 at both transcriptional and post-transcriptional levels E Paitel, C Sunyach, CA da Costa, JC Bourdon, B Vincent, F Checler Journal of Biological Chemistry 279 (1), 612-618, 2004 | 88 | 2004 |
Frederic CheclerIPMC, UMR7275 CNRS-UNSBestätigte E-Mail-Adresse bei ipmc.cnrs.fr