| Hypoxia signalling through mTOR and the unfolded protein response in cancer BG Wouters, M Koritzinsky Nature Reviews Cancer 8 (11), 851-864, 2008 | 1085 | 2008 |
| ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth M Bi, C Naczki, M Koritzinsky, D Fels, J Blais, N Hu, H Harding, I Novoa, ... The EMBO journal 24 (19), 3470-3481, 2005 | 933 | 2005 |
| The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5 KMA Rouschop, T van den Beucken, L Dubois, H Niessen, J Bussink, ... The Journal of clinical investigation 120 (1), 127-141, 2010 | 929 | 2010 |
| Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α C Koumenis, C Naczki, M Koritzinsky, S Rastani, A Diehl, N Sonenberg, ... Molecular and cellular biology 22 (21), 7405-7416, 2002 | 874 | 2002 |
| Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and-independent mechanisms and contributes to drug resistance JT Erler, CJ Cawthorne, KJ Williams, M Koritzinsky, BG Wouters, C Wilson, ... Molecular and cellular biology 24 (7), 2875-2889, 2004 | 539 | 2004 |
| Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control M Koritzinsky, MG Magagnin, T van den Beucken, R Seigneuric, ... The EMBO journal 25 (5), 1114-1125, 2006 | 417 | 2006 |
| Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance N Chan, M Koritzinsky, H Zhao, R Bindra, PM Glazer, S Powell, ... Cancer research 68 (2), 605-614, 2008 | 371 | 2008 |
| Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response VE Zannella, A Dal Pra, H Muaddi, TD McKee, S Stapleton, J Sykes, ... Clinical cancer research 19 (24), 6741-6750, 2013 | 337 | 2013 |
| Hypoxia as a target for combined modality treatments BG Wouters, SA Weppler, M Koritzinsky, W Landuyt, S Nuyts, J Theys, ... European Journal of Cancer 38 (2), 240-257, 2002 | 248 | 2002 |
| Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER T Van Den Beucken, E Koch, K Chu, R Rupaimoole, P Prickaerts, ... Nature communications 5 (1), 5203, 2014 | 247 | 2014 |
| PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS KM Rouschop, LJ Dubois, TG Keulers, T van den Beucken, P Lambin, ... Proceedings of the National Academy of Sciences 110 (12), 4622-4627, 2013 | 240 | 2013 |
| ONECUT2 is a driver of neuroendocrine prostate cancer H Guo, X Ci, M Ahmed, JT Hua, F Soares, D Lin, L Puca, A Vosoughi, ... Nature communications 10 (1), 278, 2019 | 227 | 2019 |
| Control of the hypoxic response through regulation of mRNA translation BG Wouters, T van den Beucken, MG Magagnin, M Koritzinsky, D Fels, ... Seminars in cell & developmental biology 16 (4-5), 487-501, 2005 | 213 | 2005 |
| Molecular targeting of hypoxia in radiotherapy S Rey, L Schito, M Koritzinsky, BG Wouters Advanced Drug Delivery Reviews 109, 45-62, 2017 | 186 | 2017 |
| Translational control of gene expression during hypoxia T van den Beucken, M Koritzinsky, BG Wouters Cancer biology & therapy 5 (7), 749-755, 2006 | 180 | 2006 |
| Autophagy is required during cycling hypoxia to lower production of reactive oxygen species KMA Rouschop, CHMA Ramaekers, MBE Schaaf, TGH Keulers, ... Radiotherapy and Oncology 92 (3), 411-416, 2009 | 165 | 2009 |
| The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity B Ravishankar, H Liu, R Shinde, K Chaudhary, W Xiao, J Bradley, ... Proceedings of the National Academy of Sciences 112 (34), 10774-10779, 2015 | 164 | 2015 |
| Two phases of disulfide bond formation have differing requirements for oxygen M Koritzinsky, F Levitin, T van den Beucken, RA Rumantir, NJ Harding, ... Journal of Cell Biology 203 (4), 615-627, 2013 | 162 | 2013 |
| The hypoxic proteome is influenced by gene-specific changes in mRNA translation M Koritzinsky, R Seigneuric, MG Magagnin, T van den Beucken, ... Radiotherapy and oncology 76 (2), 177-186, 2005 | 143 | 2005 |
| Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3 H Mujcic, A Nagelkerke, KMA Rouschop, S Chung, N Chaudary, PN Span, ... Clinical Cancer Research 19 (22), 6126-6137, 2013 | 139 | 2013 |
