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Kadina E. Johnston
Kadina E. Johnston
ML Protein Engineer at Merck & Co, Inc.
Bestätigte E-Mail-Adresse bei merck.com
Titel
Zitiert von
Zitiert von
Jahr
Protein sequence design with deep generative models
Z Wu, KE Johnston, FH Arnold, KK Yang
Current Opinion in Chemical Biology 65, 18-27, 2021
1562021
Advances in machine learning for directed evolution
BJ Wittmann, KE Johnston, Z Wu, FH Arnold
Current Opinion in Structural Biology 69, 11-18, 2021
1442021
FLIP: Benchmark tasks in fitness landscape inference for proteins
C Dallago, J Mou, KE Johnston, BJ Wittmann, N Bhattacharya, S Goldman, ...
bioRxiv, 2021.11. 09.467890, 2021
1372021
evSeq: Cost-Effective Amplicon Sequencing of Every Variant in a Protein Library
BJ Wittmann, KE Johnston, PJ Almhjell, FH Arnold
ACS Synthetic Biology 11 (3), 1313-1324, 2022
392022
Directed evolution of enzymatic silicon-carbon bond cleavage in siloxanes
NS Sarai, TJ Fulton, RL O’Meara, KE Johnston, S Brinkmann-Chen, ...
Science 383 (6681), 438-443, 2024
282024
DeCOIL: Optimization of Degenerate Codon Libraries for Machine Learning-Assisted Protein Engineering
J Yang, J Ducharme, KE Johnston, FZ Li, Y Yue, FH Arnold
ACS Synthetic Biology 12 (8), 2444-2454, 2023
152023
Machine learning for protein engineering
KE Johnston, C Fannjiang, BJ Wittmann, BL Hie, KK Yang, Z Wu
Machine Learning in Molecular Sciences, 277-311, 2023
142023
Double-Network Nanogel as a Nonviral Vector for DNA Delivery
M Ye, Y Wang, Y Zhao, R Xie, N Yodsanit, K Johnston, S Gong
ACS applied materials & interfaces 11 (46), 42865-42872, 2019
122019
A combinatorially complete epistatic fitness landscape in an enzyme active site
KE Johnston, PJ Almhjell, EJ Watkins-Dulaney, G Liu, NJ Porter, J Yang, ...
Proceedings of the National Academy of Sciences 121 (32), e2400439121, 2024
112024
The β-subunit of tryptophan synthase is a latent tyrosine synthase
PJ Almhjell, KE Johnston, NJ Porter, JL Kennemur, VC Bhethanabotla, ...
Nature Chemical Biology, 1-8, 2024
102024
LevSeq: Rapid Generation of Sequence-Function Data for Directed Evolution and Machine Learning
Y Long, A Mora, FZ Li, E Gürsoy, KE Johnston, FH Arnold
ACS Synthetic Biology, 2024
22024
Evaluation of Machine Learning-Assisted Directed Evolution Across Diverse Combinatorial Landscapes
FZ Li, J Yang, K Johnston, E Gursoy, Y Yue, F Arnold
bioRxiv, 2024.10. 24.619774, 2024
12024
Designing a compact, low-cost FRET microscopy platform for the undergraduate classroom
JW Rupel, SM Sdao, KE Johnston, ET Nethery, KA Gabardi, BA Ratliff, ...
The Biophysicist 1 (2), 4, 2020
12020
Acquiring Enzyme Sequence-Fitness Data at Scale Toward Predictive Methods for Enzyme Engineering
KE Johnston
California Institute of Technology, 2024
2024
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