GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death L Sborgi, S Rühl, E Mulvihill, J Pipercevic, R Heilig, H Stahlberg, ... The EMBO journal 35 (16), 1766-1778, 2016 | 1115 | 2016 |
ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation S Rühl, K Shkarina, B Demarco, R Heilig, JC Santos, P Broz Science 362 (6417), 956-960, 2018 | 618 | 2018 |
Caspase‐11 activates a canonical NLRP3 inflammasome by promoting K+ efflux S Rühl, P Broz European journal of immunology 45 (10), 2927-2936, 2015 | 548 | 2015 |
ASC filament formation serves as a signal amplification mechanism for inflammasomes MS Dick, L Sborgi, S Rühl, S Hiller, P Broz Nature communications 7 (1), 1-13, 2016 | 399 | 2016 |
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida E Meunier, P Wallet, RF Dreier, S Costanzo, L Anton, S Rühl, ... Nature immunology 16 (5), 476-484, 2015 | 371 | 2015 |
Caspase-8-dependent inflammatory responses are controlled by its adaptor, FADD, and necroptosis B Tummers, L Mari, CS Guy, BL Heckmann, DA Rodriguez, S Rühl, ... Immunity 52 (6), 994-1006. e8, 2020 | 116 | 2020 |
Regulation of lytic and non-lytic functions of gasdermin pores S Rühl, P Broz Journal of molecular biology 434 (4), 167246, 2022 | 52 | 2022 |
Disruption of coronin 1 signaling in T cells promotes allograft tolerance while maintaining anti-pathogen immunity R Jayachandran, A Gumienny, B Bolinger, S Ruehl, MJ Lang, G Fucile, ... Immunity 50 (1), 152-165. e8, 2019 | 29 | 2019 |
The gasdermin-D pore: executor of pyroptotic cell death S Rühl, P Broz Oncotarget 7 (36), 57481, 2016 | 26 | 2016 |
Non-lethal outcomes of engaging regulated cell death pathways in cancer H Kalkavan, S Rühl, JJP Shaw, DR Green Nature cancer 4 (6), 795-806, 2023 | 25 | 2023 |
Mitophagy restricts BAX/BAK-independent, Parkin-mediated apoptosis G Quarato, L Mari, NJ Barrows, M Yang, S Ruehl, MJ Chen, CS Guy, ... Science Advances 9 (21), eadg8156, 2023 | 20 | 2023 |
Corrigendum: ASC filament formation serves as a signal amplification mechanism for inflammasomes MS Dick, L Sborgi, S Rühl, S Hiller, P Broz Nature Communications 8, 2017 | 14 | 2017 |
Activation of the cAMP/protein kinase A signalling pathway by coronin 1 is regulated by cyclin‐dependent kinase 5 activity X Liu, S BoseDasgupta, R Jayachandran, V Studer, S Rühl, M Stiess, ... FEBS letters 590 (2), 279-287, 2016 | 10 | 2016 |
Anti-apoptotic BH3-only proteins inhibit Bak-dependent apoptosis S Ruehl, CS Guy, Z Li, M Yang, T Moldoveanu, DR Green BioRxiv, 2022.07. 24.499430, 2022 | 3 | 2022 |
Inhibition of BAK-mediated apoptosis by the BH3-only protein BNIP5 S Rühl, Z Li, S Srivastava, L Mari, CS Guy, M Yang, T Moldoveanu, ... Cell Death & Differentiation, 1-17, 2024 | | 2024 |
Effector mechanisms of non-canonical inflammasome activation S Rühl University_of_Basel, 2018 | | 2018 |
Investigating the Role of Coronin 1 in Beta Adrenergic Receptor Signaling and T Cell Homeostasis S Rühl Biozentrum, Universität Basel, 2013 | | 2013 |