Reduced GABAergic neuron excitability, altered synaptic connectivity, and seizures in a KCNT1 gain-of-function mouse model of childhood epilepsy AN Shore, S Colombo, WF Tobin, S Petri, ER Cullen, S Dominguez, ... Cell reports 33 (4), 2020 | 68 | 2020 |
Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission MP McCabe, ER Cullen, CM Barrows, AN Shore, KI Tooke, KA Laprade, ... Elife 9, e51440, 2020 | 65 | 2020 |
Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss K Tariq, E Cullen, SA Getz, AKS Conching, AR Goyette, ML Prina, ... Cell reports 41 (5), 2022 | 25 | 2022 |
mTORC2 inhibition improves morphological effects of PTEN loss, but does not correct synaptic dysfunction or prevent seizures ER Cullen, K Tariq, AN Shore, BW Luikart, MC Weston Journal of Neuroscience 43 (5), 827-845, 2023 | 15 | 2023 |
Hyperactivity of mTORC1-and mTORC2-dependent signaling mediates epilepsy downstream of somatic PTEN loss ER Cullen, M Safari, I Mittelstadt, MC Weston Elife 12, RP91323, 2024 | 5 | 2024 |
The paradoxical effects of K+ channel gain-of-function are mediated by GABAergic neuron hypoexcitability and hyperconnectivity AN Shore, S Colombo, WF Tobin, S Petri, ER Cullen, S Dominguez, ... bioRxiv, 2020.03. 05.978841, 2020 | 2 | 2020 |
Hyperactivity of mTORC1 or mTORC2-dependent signaling causes epilepsy downstream of somatic PTEN loss ER Cullen, I Mittelstadt, MC Weston eLife 12, 2023 | 1 | 2023 |
Roles of mTORC1 and mTORC2 in Epilepsy and Network Changes Induced by Pten Loss ER Cullen The University of Vermont and State Agricultural College, 2023 | | 2023 |
Glutamate’s Secret Interictal Life ER Cullen, MC Weston Epilepsy Currents 21 (6), 460-462, 2021 | | 2021 |
Genetic rescue of Pten-KO induced hypoexcitability and signaling changes in cortical neurons. ER Cullen | | 2021 |
mTORC1 and mTORC2 regulate distinct aspects of glutamatergic synaptic transmission MP McCabe, ER Cullen, CM Barrows, AN Shore, KI Tooke, MC Weston bioRxiv, 731554, 2019 | | 2019 |