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Erin R. Cullen
Erin R. Cullen
Postdoctoral Researcher, Columbia University Irving Medical Center
Bestätigte E-Mail-Adresse bei cumc.columbia.edu
Titel
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Reduced GABAergic neuron excitability, altered synaptic connectivity, and seizures in a KCNT1 gain-of-function mouse model of childhood epilepsy
AN Shore, S Colombo, WF Tobin, S Petri, ER Cullen, S Dominguez, ...
Cell reports 33 (4), 2020
682020
Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission
MP McCabe, ER Cullen, CM Barrows, AN Shore, KI Tooke, KA Laprade, ...
Elife 9, e51440, 2020
652020
Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss
K Tariq, E Cullen, SA Getz, AKS Conching, AR Goyette, ML Prina, ...
Cell reports 41 (5), 2022
252022
mTORC2 inhibition improves morphological effects of PTEN loss, but does not correct synaptic dysfunction or prevent seizures
ER Cullen, K Tariq, AN Shore, BW Luikart, MC Weston
Journal of Neuroscience 43 (5), 827-845, 2023
152023
Hyperactivity of mTORC1-and mTORC2-dependent signaling mediates epilepsy downstream of somatic PTEN loss
ER Cullen, M Safari, I Mittelstadt, MC Weston
Elife 12, RP91323, 2024
52024
The paradoxical effects of K+ channel gain-of-function are mediated by GABAergic neuron hypoexcitability and hyperconnectivity
AN Shore, S Colombo, WF Tobin, S Petri, ER Cullen, S Dominguez, ...
bioRxiv, 2020.03. 05.978841, 2020
22020
Hyperactivity of mTORC1 or mTORC2-dependent signaling causes epilepsy downstream of somatic PTEN loss
ER Cullen, I Mittelstadt, MC Weston
eLife 12, 2023
12023
Roles of mTORC1 and mTORC2 in Epilepsy and Network Changes Induced by Pten Loss
ER Cullen
The University of Vermont and State Agricultural College, 2023
2023
Glutamate’s Secret Interictal Life
ER Cullen, MC Weston
Epilepsy Currents 21 (6), 460-462, 2021
2021
Genetic rescue of Pten-KO induced hypoexcitability and signaling changes in cortical neurons.
ER Cullen
2021
mTORC1 and mTORC2 regulate distinct aspects of glutamatergic synaptic transmission
MP McCabe, ER Cullen, CM Barrows, AN Shore, KI Tooke, MC Weston
bioRxiv, 731554, 2019
2019
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