Beneficial and detrimental effects of reactive oxygen species on lifespan: a comprehensive review of comparative and experimental studies HJ Shields, A Traa, JM Van Raamsdonk Frontiers in cell and developmental biology 9, 628157, 2021 | 415 | 2021 |
Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework AA Cohen, BK Kennedy, U Anglas, AM Bronikowski, J Deelen, F Dufour, ... Mechanisms of ageing and development 191, 111316, 2020 | 112 | 2020 |
Exercise preserves physical fitness during aging through AMPK and mitochondrial dynamics JC Campos, LH Marchesi Bozi, B Krum, LR Grassmann Bechara, ... Proceedings of the National Academy of Sciences 120 (2), e2204750120, 2023 | 61 | 2023 |
Disruption of mitochondrial dynamics increases stress resistance through activation of multiple stress response pathways E Machiela, T Liontis, DJ Dues, PD Rudich, A Traa, L Wyman, C Kaufman, ... The FASEB Journal 34 (6), 8475, 2020 | 43 | 2020 |
Compounds that extend longevity are protective in neurodegenerative diseases and provide a novel treatment strategy for these devastating disorders SK Soo, PD Rudich, A Traa, N Harris-Gauthier, HJ Shields, ... Mechanisms of Ageing and Development 190, 111297, 2020 | 34 | 2020 |
Targeting Mitochondrial Network Disorganization is Protective in C. elegans Models of Huntington’s Disease E Machiela, PD Rudich, A Traa, U Anglas, SK Soo, MM Senchuk, ... Aging and disease 12 (7), 1753–1772, 2021 | 29 | 2021 |
Activation of mitochondrial unfolded protein response protects against multiple exogenous stressors SK Soo, A Traa, PD Rudich, M Mistry, JM Van Raamsdonk Life Science Alliance 4 (12), 2021 | 24 | 2021 |
Genetic basis of enhanced stress resistance in long‐lived mutants highlights key role of innate immunity in determining longevity SK Soo, A Traa, ZD Rudich, A Moldakozhayev, M Mistry, ... Aging Cell 22 (2), e13740, 2023 | 23 | 2023 |
Mitochondrial thioredoxin system is required for enhanced stress resistance and extended longevity in long-lived mitochondrial mutants N Harris-Gauthier, A Traa, A AlOkda, A Moldakozhayev, U Anglas, ... Redox Biology 53, 102335, 2022 | 19 | 2022 |
Identification of Novel Therapeutic Targets for Polyglutamine Diseases That Target Mitochondrial Fragmentation A Traa, E Machiela, PD Rudich, SK Soo, MM Senchuk, ... International Journal of Molecular Sciences 22 (24), 13447, 2021 | 12 | 2021 |
Endosomal trafficking protein TBC‐2 modulates stress resistance and lifespan through DAF‐16‐dependent and independent mechanisms A Traa, SK Soo, A AlOkda, B Ko, CE Rocheleau, JM Van Raamsdonk Aging Cell 22 (3), e13762, 2023 | 6 | 2023 |
A journey to ‘tame a small metazoan organism’, ‡ seen through the artistic eyes of C. elegans researchers E Gourgou, AR Willis, S Giunti, MJ De Rosa, AG Charlesworth, ... Journal of Neurogenetics 34 (3-4), 549-560, 2020 | 5 | 2020 |
Overexpression of mitochondrial fission or mitochondrial fusion genes enhances resilience and extends longevity A Traa, A Keil, A AlOkda, S Jacob‐Tomas, AA Tamez González, S Zhu, ... Aging Cell, e14262, 2024 | 4 | 2024 |
Developmental disruption of the mitochondrial fission gene drp-1 extends the longevity of daf-2 insulin/IGF-1 receptor mutant A Traa, AA Tamez González, JM Van Raamsdonk GeroScience, 1-26, 2024 | 1 | 2024 |
Mitochondrial superoxide acts in the intestine to extend longevity T Liontis, MM Senchuk, S Zhu, S Jacob-Tomas, U Anglas, A Traa, SK Soo, ... bioRxiv, 2024.09. 13.612915, 2024 | | 2024 |
Endosomal trafficking protein TBC-2 is required for the longevity of long-lived mitochondrial mutants A Traa, H Shields, A AlOkda, ZD Rudich, B Ko, JM Van Raamsdonk Frontiers in Aging 4, 1145198, 2023 | | 2023 |