UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development K Agger, PAC Cloos, J Christensen, D Pasini, S Rose, J Rappsilber, ... Nature 449 (7163), 731-734, 2007 | 1598 | 2007 |
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions AP Bracken, N Dietrich, D Pasini, KH Hansen, K Helin Genes & development 20 (9), 1123-1136, 2006 | 1572 | 2006 |
EZH2 is downstream of the pRB‐E2F pathway, essential for proliferation and amplified in cancer AP Bracken, D Pasini, M Capra, E Prosperini, E Colli, K Helin The EMBO journal, 2003 | 1497 | 2003 |
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity K Williams, J Christensen, MT Pedersen, JV Johansen, PAC Cloos, ... Nature 473 (7347), 343-348, 2011 | 1143 | 2011 |
Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity D Pasini, AP Bracken, MR Jensen, EL Denchi, K Helin The EMBO journal 23 (20), 4061-4071, 2004 | 1121 | 2004 |
Role of TET enzymes in DNA methylation, development, and cancer KD Rasmussen, K Helin Genes & development 30 (7), 733-750, 2016 | 1110 | 2016 |
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells AP Bracken, D Kleine-Kohlbrecher, N Dietrich, D Pasini, G Gargiulo, ... Genes & development 21 (5), 525-530, 2007 | 1055 | 2007 |
Molecular mechanisms and potential functions of histone demethylases SM Kooistra, K Helin Nature reviews Molecular cell biology 13 (5), 297-311, 2012 | 1036 | 2012 |
Transcriptional regulation by Polycomb group proteins L Di Croce, K Helin Nature structural & molecular biology 20 (10), 1147-1155, 2013 | 1026 | 2013 |
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis H Müller, AP Bracken, R Vernell, MC Moroni, F Christians, E Grassilli, ... Genes & development 15 (3), 267-285, 2001 | 953 | 2001 |
The putative oncogene GASC1 demethylates tri-and dimethylated lysine 9 on histone H3 PAC Cloos, J Christensen, K Agger, A Maiolica, J Rappsilber, T Antal, ... Nature 442 (7100), 307-311, 2006 | 906 | 2006 |
A model for transmission of the H3K27me3 epigenetic mark KH Hansen, AP Bracken, D Pasini, N Dietrich, SS Gehani, A Monrad, ... Nature cell biology 10 (11), 1291-1300, 2008 | 850 | 2008 |
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F K Helin, JA Lees, M Vidal, N Dyson, E Harlow, A Fattaey Cell 70 (2), 337-350, 1992 | 841 | 1992 |
The polycomb group protein Suz12 is required for embryonic stem cell differentiation D Pasini, AP Bracken, JB Hansen, M Capillo, K Helin Molecular and cellular biology, 2007 | 825 | 2007 |
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease PAC Cloos, J Christensen, K Agger, K Helin Genes & development 22 (9), 1115-1140, 2008 | 820 | 2008 |
Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas S Bender, Y Tang, AM Lindroth, V Hovestadt, DTW Jones, M Kool, ... Cancer cell 24 (5), 660-672, 2013 | 813 | 2013 |
Apaf-1 is a transcriptional target for E2F and p53 MC Moroni, ES Hickman, EL Denchi, G Caprara, E Colli, F Cecconi, ... Nature cell biology 3 (6), 552-558, 2001 | 808 | 2001 |
Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein K Helin, ED Harlow, A Fattaey Molecular and cellular biology 13 (10), 6501-6508, 1993 | 719 | 1993 |
Polycomb group proteins: navigators of lineage pathways led astray in cancer AP Bracken, K Helin Nature Reviews Cancer 9 (11), 773-784, 2009 | 717 | 2009 |
The E2F family: specific functions and overlapping interests C Attwooll, EL Denchi, K Helin The EMBO journal 23 (24), 4709-4716, 2004 | 717 | 2004 |