| Stem cell fate in cancer growth, progression and therapy resistance NK Lytle, AG Barber, T Reya Nature Reviews Cancer 18 (11), 669-680, 2018 | 614 | 2018 |
| Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring Y Shi, W Gao, NK Lytle, P Huang, X Yuan, AM Dann, M Ridinger-Saison, ... Nature 569 (7754), 131-135, 2019 | 388 | 2019 |
| Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis RL Williams-Karnesky, US Sandau, TA Lusardi, NK Lytle, JM Farrell, ... The Journal of clinical investigation 123 (8), 3552-3563, 2013 | 281 | 2013 |
| Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma RG Fox, NK Lytle, DV Jaquish, FD Park, T Ito, J Bajaj, CS Koechlein, ... Nature 534 (7607), 407-411, 2016 | 151 | 2016 |
| A multiscale map of the stem cell state in pancreatic adenocarcinoma NK Lytle, LP Ferguson, N Rajbhandari, K Gilroy, RG Fox, A Deshpande, ... Cell 177 (3), 572-586. e22, 2019 | 147 | 2019 |
| Epigenetic and transcriptomic profiling of mammary gland development and tumor models disclose regulators of cell state plasticity C Dravis, CY Chung, NK Lytle, J Herrera-Valdez, G Luna, CL Trejo, ... Cancer cell 34 (3), 466-482. e6, 2018 | 139 | 2018 |
| Stress-activated NRF2-MDM2 cascade controls neoplastic progression in pancreas J Todoric, L Antonucci, G Di Caro, N Li, X Wu, NK Lytle, D Dhar, ... Cancer cell 32 (6), 824-839. e8, 2017 | 131 | 2017 |
| Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade X Wu, W Zhang, J Font-Burgada, T Palmer, AS Hamil, SK Biswas, ... Proceedings of the National Academy of Sciences 111 (38), 13870-13875, 2014 | 127 | 2014 |
| CD98-mediated adhesive signaling enables the establishment and propagation of acute myelogenous leukemia J Bajaj, T Konuma, NK Lytle, HY Kwon, JN Ablack, JM Cantor, D Rizzieri, ... Cancer cell 30 (5), 792-805, 2016 | 113 | 2016 |
| Adenosine augmentation ameliorates psychotic and cognitive endophenotypes of schizophrenia HY Shen, P Singer, N Lytle, CJ Wei, JQ Lan, RL Williams-Karnesky, ... The Journal of clinical investigation 122 (7), 2567-2577, 2012 | 109 | 2012 |
| Tetraspanin 3 is required for the development and propagation of acute myelogenous leukemia HY Kwon, J Bajaj, T Ito, A Blevins, T Konuma, J Weeks, NK Lytle, ... Cell stem cell 17 (2), 152-164, 2015 | 89 | 2015 |
| Local disruption of glial adenosine homeostasis in mice associates with focal electrographic seizures: a first step in epileptogenesis? T Li, N Lytle, JQ Lan, US Sandau, D Boison Glia 60 (1), 83-95, 2012 | 78 | 2012 |
| Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury Z Ma, NK Lytle, B Chen, N Jyotsana, SW Novak, CJ Cho, L Caplan, ... Gastroenterology 162 (2), 604-620. e20, 2022 | 67 | 2022 |
| Tuft cells inhibit pancreatic tumorigenesis in mice by producing prostaglandin D2 KE DelGiorno, CY Chung, V Vavinskaya, HC Maurer, SW Novak, NK Lytle, ... Gastroenterology 159 (5), 1866-1881. e8, 2020 | 60 | 2020 |
| The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila JE Duncan, NK Lytle, A Zuniga, LSB Goldstein PloS one 8 (6), e68324, 2013 | 59 | 2013 |
| Caffeine prevents acute mortality after TBI in rats without increased morbidity TA Lusardi, NK Lytle, C Szybala, D Boison Experimental neurology 234 (1), 161-168, 2012 | 54 | 2012 |
| Glycine transporter 1 is a target for the treatment of epilepsy HY Shen, EA Van Vliet, KA Bright, M Hanthorn, NK Lytle, J Gorter, ... Neuropharmacology 99, 554-565, 2015 | 49 | 2015 |
| Intermittent cold exposure enhances fat accumulation in mice HS Yoo, L Qiao, C Bosco, LH Leong, N Lytle, GS Feng, NW Chi, J Shao PLoS One 9 (5), e96432, 2014 | 46 | 2014 |
| Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling S Bersini, NK Lytle, R Schulte, L Huang, GM Wahl, MW Hetzer Life science alliance 3 (1), 2020 | 44 | 2020 |
| Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders YC Li, NK Lytle, ST Gammon, L Wang, TK Hayes, MN Sutton, RC Bast Jr, ... Proceedings of the National Academy of Sciences 117 (22), 12121-12130, 2020 | 20 | 2020 |