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Olli Kärkkäinen
Olli Kärkkäinen
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Microbiota-derived metabolites as drivers of gut–brain communication
H Ahmed, Q Leyrolle, V Koistinen, O Kärkkäinen, S Layé, N Delzenne, ...
Gut microbes 14 (1), 2102878, 2022
1902022
Metabolic signature of extracellular vesicles depends on the cell culture conditions
M Palviainen, H Saari, O Kärkkäinen, J Pekkinen, S Auriola, M Yliperttula, ...
Journal of extracellular vesicles 8 (1), 1596669, 2019
1422019
“Notame”: workflow for non-targeted LC–MS metabolic profiling
A Klåvus, M Kokla, S Noerman, VM Koistinen, M Tuomainen, I Zarei, ...
Metabolites 10 (4), 135, 2020
1092020
Contribution of gut microbiota to metabolism of dietary glycine betaine in mice and in vitro colonic fermentation
VM Koistinen, O Kärkkäinen, K Borewicz, I Zarei, J Jokkala, V Micard, ...
Microbiome 7, 1-14, 2019
932019
Maternal microbiota-derived metabolic profile in fetal murine intestine, brain and placenta
T Pessa-Morikawa, A Husso, O Kärkkäinen, V Koistinen, K Hanhineva, ...
BMC microbiology 22 (1), 46, 2022
672022
Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: a cross-sectional study in obese patients
Q Leyrolle, R Cserjesi, MDGH Mulders, G Zamariola, S Hiel, ...
Clinical nutrition 40 (4), 2035-2044, 2021
572021
Diets rich in whole grains increase betainized compounds associated with glucose metabolism
O Kärkkäinen, MA Lankinen, M Vitale, J Jokkala, J Leppänen, V Koistinen, ...
The American journal of clinical nutrition 108 (5), 971-979, 2018
542018
Heart specific PGC-1α deletion identifies metabolome of cardiac restricted metabolic heart failure
O Kärkkäinen, T Tuomainen, M Mutikainen, M Lehtonen, JL Ruas, ...
Cardiovascular research 115 (1), 107-118, 2019
492019
HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage
S Loppi, N Kolosowska, O Kärkkäinen, P Korhonen, M Huuskonen, ...
Brain, behavior, and immunity 73, 670-681, 2018
402018
Changes in the human metabolome associated with alcohol use: a review
T Voutilainen, O Kärkkäinen
Alcohol and Alcoholism 54 (3), 225-234, 2019
362019
Diet-and microbiota-related metabolite, 5-aminovaleric acid betaine (5-AVAB), in health and disease
R Haikonen, O Kärkkäinen, V Koistinen, K Hanhineva
Trends in Endocrinology & Metabolism 33 (7), 463-480, 2022
342022
Whole grain intake associated molecule 5-aminovaleric acid betaine decreases β-oxidation of fatty acids in mouse cardiomyocytes
O Kärkkäinen, T Tuomainen, V Koistinen, M Tuomainen, J Leppänen, ...
Scientific reports 8 (1), 13036, 2018
322018
Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET)
M Tuomainen, O Kärkkäinen, J Leppänen, S Auriola, M Lehtonen, ...
The American journal of clinical nutrition 110 (5), 1108-1118, 2019
312019
A non-targeted LC-MS profiling reveals elevated levels of carnitine precursors and trimethylated compounds in the cord plasma of pre-eclamptic infants
T Jääskeläinen, O Kärkkäinen, J Jokkala, K Litonius, S Heinonen, ...
Scientific reports 8 (1), 14616, 2018
302018
mGluR1/5 receptor densities in the brains of alcoholic subjects: a whole-hemisphere autoradiography study
J Kupila, O Kärkkäinen, V Laukkanen, E Tupala, J Tiihonen, M Storvik
Psychiatry Research: Neuroimaging 212 (3), 245-250, 2013
302013
Metabolic profiling of high egg consumption and the associated lower risk of type 2 diabetes in middle‐aged finnish men
S Noerman, O Kärkkäinen, A Mattsson, J Paananen, M Lehtonen, T Nurmi, ...
Molecular nutrition & food research 63 (5), 1800605, 2019
262019
A non-targeted LC–MS metabolic profiling of pregnancy: longitudinal evidence from healthy and pre-eclamptic pregnancies
T Jääskeläinen, O Kärkkäinen, J Jokkala, A Klåvus, S Heinonen, ...
Metabolomics 17, 1-12, 2021
252021
Decreased serum total cholesterol is associated with a history of childhood physical violence in depressed outpatients
SL Kraav, T Tolmunen, O Kärkkäinen, A Ruusunen, H Viinamäki, ...
Psychiatry research 272, 326-333, 2019
222019
AMPA receptors in post-mortem brains of Cloninger type 1 and 2 alcoholics: a whole-hemisphere autoradiography study
O Kärkkäinen, J Kupila, M Häkkinen, V Laukkanen, E Tupala, ...
Psychiatry Research: Neuroimaging 214 (3), 429-434, 2013
222013
Impacts of maternal microbiota and microbial metabolites on fetal intestine, brain, and placenta
A Husso, T Pessa-Morikawa, VM Koistinen, O Kärkkäinen, HN Kwon, ...
BMC biology 21 (1), 207, 2023
212023
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