Regulation of alternative splicing by histone modifications RF Luco, Q Pan, K Tominaga, BJ Blencowe, OM Pereira-Smith, T Misteli Science 327 (5968), 996-1000, 2010 | 1278 | 2010 |
Activation of innate immune antiviral responses by Nod2 A Sabbah, TH Chang, R Harnack, V Frohlich, K Tominaga, PH Dube, ... Nature immunology 10 (10), 1073-1080, 2009 | 949 | 2009 |
Aberrant cell cycle checkpoint function and early embryonic death in Chk1−/− mice H Takai, K Tominaga, N Motoyama, YA Minamishima, H Nagahama, ... Genes & development 14 (12), 1439-1447, 2000 | 638 | 2000 |
A point mutation in the mitochondrial tRNALeu (UUR) gene in MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes) Y Kobayashi, MY Momoi, K Tominaga, T Momoi, K Nihei, M Yanagisawa, ... Biochemical and biophysical research communications 173 (3), 816-822, 1990 | 466 | 1990 |
Cell cycle-dependent and ATM-independent expression of human Chk1 kinase Y Kaneko, N Watanabe, H Morisaki, H Akita, A Fujimoto, K Tominaga, ... Oncogene 18 (25), 3673-3681, 1999 | 183 | 1999 |
Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53 K Tominaga, H Morisaki, Y Kaneko, A Fujimoto, T Tanaka, M Ohtsubo, ... Journal of Biological Chemistry 274 (44), 31463-31467, 1999 | 136 | 1999 |
Respiration-deficient cells are caused by a single point mutation in the mitochondrial tRNA-Leu (UUR) gene in mitochondrial myopathy, encephalopathy, lactic acidosis, and … Y Kobayashi, MY Momoi, K Tominaga, H Shimoizumi, K Nihei, ... American journal of human genetics 49 (3), 590, 1991 | 133 | 1991 |
The emerging role of senescent cells in tissue homeostasis and pathophysiology K Tominaga Pathobiology of Aging & Age-Related Diseases 5 (1), 27743, 2015 | 123 | 2015 |
MRG15 regulates embryonic development and cell proliferation K Tominaga, B Kirtane, JG Jackson, Y Ikeno, T Ikeda, C Hawks, JR Smith, ... Molecular and cellular biology 25 (8), 2924-2937, 2005 | 91 | 2005 |
Lipopolysaccharide tolerance in murine peritoneal macrophages induces downregulation of the lipopolysaccharide signal transduction pathway through mitogen-activated protein … K Tominaga, S Saito, M Matsuura, M Nakano Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1450 (2), 130-144, 1999 | 91 | 1999 |
Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice VI Pérez, LA Cortez, CM Lew, M Rodriguez, CR Webb, H Van Remmen, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2011 | 87 | 2011 |
MRG15 is required for pre-mRNA splicing and spermatogenesis N Iwamori, K Tominaga, T Sato, K Riehle, T Iwamori, Y Ohkawa, C Coarfa, ... Proceedings of the National Academy of Sciences 113 (37), E5408-E5415, 2016 | 78 | 2016 |
Genetics of cellular senescence K Tominaga, A Olgun, JR Smith, OM Pereira-Smith Mechanisms of ageing and development 123 (8), 927-936, 2002 | 74 | 2002 |
Potent prostaglandin A1 analogs that suppress tumor cell growth through induction of p21 and reduction of cyclin E M Tanikawa, K Yamada, K Tominaga, H Morisaki, Y Kaneko, K Ikeda, ... Journal of Biological Chemistry 273 (29), 18522-18527, 1998 | 64 | 1998 |
Biological Characterization of Endotoxins Released from Antibiotic-Treated Pseudomonas aeruginosa and Escherichia coli T Kirikae, F Kirikae, S Saito, K Tominaga, H Tamura, Y Uemura, T Yokochi, ... Antimicrobial agents and chemotherapy 42 (5), 1015-1021, 1998 | 61 | 1998 |
MRG15, a component of HAT and HDAC complexes, is essential for proliferation and differentiation of neural precursor cells M Chen, M Takano‐Maruyama, OM Pereira‐Smith, GO Gaufo, ... Journal of neuroscience research 87 (7), 1522-1531, 2009 | 60 | 2009 |
Translational repression of the McKusick–Kaufman syndrome transcript by unique upstream open reading frames encoding mitochondrial proteins with alternative polyadenylation sites C Akimoto, E Sakashita, K Kasashima, K Kuroiwa, K Tominaga, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (3), 2728-2738, 2013 | 50 | 2013 |
An amino acid change in the non-structural NS2 protein of an influenza A virus mutant is responsible for the generation of defective interfering (DI) particles by amplifying DI … T Odagiri, K Tominaga, K Tobita, S Ohta Journal of general virology 75 (1), 43-53, 1994 | 50 | 1994 |
Mrg15 null and heterozygous mouse embryonic fibroblasts exhibit DNA-repair defects post exposure to gamma ionizing radiation SN Garcia, BM Kirtane, AJ Podlutsky, OM Pereira-Smith, K Tominaga FEBS letters 581 (27), 5275-5281, 2007 | 44 | 2007 |
Emerging role of the MORF/MRG gene family in various biological processes, including aging M Chen, K Tominaga, OM Pereira‐Smith Annals of the New York Academy of Sciences 1197 (1), 134-141, 2010 | 42 | 2010 |