| Variations on a (t) heme—novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily AW Munro, HM Girvan, KJ McLean Natural product reports 24 (3), 585-609, 2007 | 341 | 2007 |
| Applications of microbial cytochrome P450 enzymes in biotechnology and synthetic biology HM Girvan, AW Munro Current opinion in chemical biology 31, 136-145, 2016 | 302 | 2016 |
| Cytochrome P450–redox partner fusion enzymes AW Munro, HM Girvan, KJ McLean Biochimica et Biophysica Acta (BBA)-General Subjects 1770 (3), 345-359, 2007 | 282 | 2007 |
| What makes a P450 tick? AW Munro, HM Girvan, AE Mason, AJ Dunford, KJ McLean Trends in Biochemical Sciences 38 (3), 140-150, 2013 | 241 | 2013 |
| The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase R Neeli, HM Girvan, A Lawrence, MJ Warren, D Leys, NS Scrutton, ... FEBS letters 579 (25), 5582-5588, 2005 | 163 | 2005 |
| Heme sensor proteins HM Girvan, AW Munro Journal of Biological Chemistry 288 (19), 13194-13203, 2013 | 149 | 2013 |
| Flavocytochrome P450 BM3: an update on structure and mechanism of a biotechnologically important enzyme AJ Warman, O Roitel, R Neeli, HM Girvan, HE Seward, SA Murray, ... Biochemical Society Transactions 33 (4), 747-753, 2005 | 136 | 2005 |
| Biophysical Characterization of the Sterol Demethylase P450 from Mycobacterium tuberculosis, Its Cognate Ferredoxin, and Their Interactions KJ McLean, AJ Warman, HE Seward, KR Marshall, HM Girvan, ... Biochemistry 45 (27), 8427-8443, 2006 | 107 | 2006 |
| Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set HM Girvan, KR Marshall, RJ Lawson, D Leys, MG Joyce, J Clarkson, ... Journal of Biological Chemistry 279 (22), 23274-23286, 2004 | 99 | 2004 |
| Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets: new heme ligation states influence conformational equilibria in … HM Girvan, HE Seward, HS Toogood, MR Cheesman, D Leys, AW Munro Journal of Biological Chemistry 282 (1), 564-572, 2007 | 94 | 2007 |
| Catalytic determinants of alkene production by the cytochrome P450 peroxygenase OleTJE S Matthews, JD Belcher, KL Tee, HM Girvan, KJ McLean, SEJ Rigby, ... Journal of Biological Chemistry 292 (12), 5128-5143, 2017 | 90 | 2017 |
| A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme MG Joyce, HM Girvan, AW Munro, D Leys Journal of Biological Chemistry 279 (22), 23287-23293, 2004 | 87 | 2004 |
| The crystal structure of the FAD/NADPH‐binding domain of flavocytochrome P450 BM3 MG Joyce, IS Ekanem, O Roitel, AJ Dunford, R Neeli, HM Girvan, ... The FEBS journal 279 (9), 1694-1706, 2012 | 68 | 2012 |
| Flavocytochrome P450 BM3 and the origin of CYP102 fusion species HM Girvan, TN Waltham, R Neeli, HF Collins, KJ McLean, NS Scrutton, ... Biochemical Society Transactions 34 (6), 1173-1177, 2006 | 61 | 2006 |
| Interaction of nitric oxide with cytochrome P450 BM3 LG Quaroni, HE Seward, KJ McLean, HM Girvan, TWB Ost, MA Noble, ... Biochemistry 43 (51), 16416-16431, 2004 | 55 | 2004 |
| Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: implications for the mechanism of electron transfer in the P450 BM3 dimer HM Girvan, AJ Dunford, R Neeli, IS Ekanem, TN Waltham, MG Joyce, ... Archives of biochemistry and biophysics 507 (1), 75-85, 2011 | 54 | 2011 |
| Cytochrome P450/redox partner fusion enzymes: biotechnological and toxicological prospects KJ McLean, HM Girvan, AW Munro Expert opinion on drug metabolism & toxicology 3 (6), 847-863, 2007 | 53 | 2007 |
| Heme and hemoproteins AW Munro, HM Girvan, KJ McLean, MR Cheesman, D Leys Tetrapyrroles: Birth, Life and Death, 160-183, 2009 | 46 | 2009 |
| Novel haem co-ordination variants of flavocytochrome P450 BM3 HM Girvan, HS Toogood, RE Littleford, HE Seward, WE Smith, IS Ekanem, ... Biochemical Journal 417 (1), 65-80, 2009 | 46 | 2009 |
| Clobetasol propionate is a heme-mediated selective inhibitor of human cytochrome P450 3A5 WC Wright, J Chenge, J Wang, HM Girvan, L Yang, SC Chai, AD Huber, ... Journal of medicinal chemistry 63 (3), 1415-1433, 2020 | 42 | 2020 |
